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AR/FE/LV
Determinants of airway resistance/forced expirations/lung volumes-CJ- 1/10/13
| Question | Answer |
|---|---|
| Two main forces that oppose air movement | Compliance and frictional resistance |
| What is the predominant resistance to airway flow? | Airway resistance (80%) |
| Sources of viscous resistance | Lung and chest wall as well as diaphragm and abdomen |
| Resistance is measured by measuring the | Pressure drop |
| Equation for measuring resistance | R= Change in pressure/Flow |
| Three types of air flow through airways | Laminar, turbulent, transitional |
| Laminar flow in the lungs is seen in the | Terminal bronchioles |
| Turbulent flow in the respiratory system is seen in the | Trachea |
| Relationship between Radius and Resistance in laminar flow | Resistance is inversely proportional to radius^4 |
| Relationship between radius and length in laminar flow | Resistance is inversely proportional to length |
| An increase in velocity does what to the chance of turbulent flow | Increases |
| An increase in diameter does what to the chance of turbulent flow | Increases |
| An increase in density does what to the chance of turbulent flow | Increases |
| An increase in viscosity does what to the chance of turbulent flow | Decreases |
| The main site of airway resistance in | The medium-sized bronchi |
| Define radial traction | As alveoli expand, they exert tension on airways and pull them open |
| What factors affect smooth muscle tone and affect airway resistance? | Irritants, parasympathetic tone, and B2 stimulants |
| What increases airways resistance in Chronic bronchitis | Hyper secretions of mucus |
| What increases airway resistance in asthma | Increase in smooth muscle ton due to hypersensitivity |
| What increases airways resistance in emphysema | Decreased radial traction and decreased diameter |
| Forced expiration changes the main site of resistance to | Peripheral airways because they are compressed |
| Define transairway pressure | Pressure difference across the airway wall |
| What determines airway patency | Transairway pressure |
| During inspiration and passive expiration, the transaiway pressure is | Positive |
| When you squeeze the lungs, the pleural pressure becomes | Positive |
| What lung volumes cannot be measured by spirometry? | Functional residual capacity, residual volume and total lung capacity |
| Obstructive disorders present with | Increased airway resistance and large lung volumes |
| Restrictive disorders present with | Normal/decreased airway resistance and small lung volumes |
| FEV1 | Volume exhaled in 1st second |
| FVC | Total volume exhaled |
| Normal FEV:FVC | .8 |
| Obstructive FEV:FVC ratio | Less than .8 |
| Restrictive FEV:FVC ratio | Greater than or equal to .8 |
| What factors determine FEV1 | Lung volume, Airway collapse, Airway resistance |
| Forced expiratory flow rate in obstructive disorders is | Lower than 3.5 |
| Forced expiratory flow rate in restrictive disorders is | Greater than 3.5 |
| Flow-volume curve for obstructive disorders presents with a | "Scooped out" area |
| An interthoracic airway obstruction flow-volume curve will be | Flattened on the top (expiration) |
| An extrathoracic airway obstruction flow-volume curve will be | Flattened on the bottom (inspiration) |
| A fixed obstruction flow-volume curve will be | Flattened in both expiration and inspiration |