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Lecture 11

Myocardial Disease, Pericardial Disease

What is Dilated Cardiomyopathy Biventricular dilation with thin walls enlarged and flabby with eventual 4 chamber dilation
What are some secondary causes of dilated cardiomyopathy Drugs and toxins, Chemotherapy, Preganancy, Metabolic Disorders
What are some metabolic Disorders associated with dilated cardiomyopathy Hyperthyroid, Hypothyroidism, Thiamine deficiency
how do people with dilated cardiomyopathy present dyspnea and fatigue: pulmonary congestion, palpitations, S4 gallop, S3
What is Hypertrophic cardiomyopathy Left ventricular hypertrophy and often RV hypertrophy increases muscle mass resulting in a hypercontractile heart
What are the two main types of hypertrophic cardiomyopathies Asymmetrical and Symmetrical
Where does the thickening in asymmetrical cardiomyopathy occur most often The basal portion of the ventricular septum
How is symmetrical hypertrophic cardiomyopathy different from asymmetric symmetric is concentric hypertrophy of both venricles with NO LV OUTFLOW OBSTRUCTION
Sudden death is common in children and young men with familial forms of this cardiomyopathy hypertrophic
Where do you see endomyocardial fibrosis in subtropical areas especially equatorial Aftica usually in children and young adults
what are the cardiomyopathies classified as the cytoskeletalopathies Dilated cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, cariocutaneous syndromes
what are the cardiomyopathies classified as sarcomyopathy hypertrophic and restrictive cardiomyopahties
what are the cardiomyopathies classified as the channelopathies long and short QT syndromes, Brugada syndrome, Catecholaminergic polymorphic VT
what is Myocarditis inflammation of the myocardium in which the inflammatory process is not the primary cause of the myocardial injury
what is primary myocarditis when the myocardium is the principle target of the inflammatory process usually infectious
what is secondary myocarditis myocardial inflammation occurs as part of a systemic inflammatory process usually autoimmune or allergic
what is the most common pathogenesis of myocarditis infectious agens are most common (viral most common)
what are some viruses that can cause myocarditis enteroviruses Coxsackie A&B, polio, ECHO, Influenza, CMV, HIV
what are some common bacteria that cause myocarditis corynebacterium, borrelia, rickettsial
what are some common immunological causes of myocarditis SLE, Poststreptococcal (rheumatic fever), radiation, drugs toxicity/hypersensitivity
what is primary pericarditis inflammation involving the pericardium alone (rare) most pericarditis is secondary
what is the most common type of pericarditis fibrinous (bread and butter appearance)
When you see Caseous necrosis within the pericardial sac you should think ? until proven otherwise Tuberculosis
what are the two clinical varients of chronic pericarditis Adhesive and Constrictive Pericarditis
what is cardiac tamponade an often lethal complication of hemopericardium
what is the most common primary cardiac tumor myxoma (90% are atrial with a 4:1 L:R ratio)
Created by: UVAPATH3



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