click below
click below
Normal Size Small Size show me how
development of back
| Question | Answer |
|---|---|
| where is neural tube and neural crest cell develope from? | Epiblast-> ectoderm -> neura tube and neural crest cell |
| Neuroepithelial layer | give rise to all spinal neurons and some support cell |
| Mantle layer | form by neuroepithelial cell that divide and differentiate into neuroblast cells |
| Marginal layer | region that will contain white matter + Meninges |
| Meninges | layer of membrane that give rise to CNS |
| after thickening of neural tube, what does mantle layer differentiate into? | 1) Alar plate (posterior horn) 2) Basal plate (anterior horn) |
| Alar plate | formed from mantle layer, it formed posterior horn (sensory neuron) |
| Basal plate | formed from mantle layer, it formed anterior horn (motor neuron) |
| Intermediate horm | formed between posterior and anterior horns |
| where does motor and sensory neuron meet? | spinal nerve |
| where does Posterior ramus innverate? | Motor and sensory of dermomyotome of Back example: erretus and intrinsic muscle of back |
| Where does anteriro ramus innverate with? | Motor and sensory of dermomyotome of body wall and limbs |
| Ramus vs Root | Root contribute to ramus Root contain either sensory (posterior root) or motor (anterior root) neurons Ramus contains both motor and sensory |
| landmark of dermatome | C3=neck, T4=nipple, T10=umbilical, L1-Inguinal line, C8=5th digit of hand, C6=Pollex, L4=knee, L5=anterior ankle and foot, S2=posterior lower limb |
| where does anterior ramus goes to? | To the hypomere: skin (everywhere except midline of back) and to hypaxial (extrinsic0 muscle |
| Where does posterior ramus goes to? | To the epimere: skin along the midline of back (to the coastal angle) and to epaxial (instrinsic) muscle |
| Hypomere | skin (everywhere except midline of back) and to the hypaxial (extrinsic muscle) inneverated by anterior ramus |
| Epimere | Skin along the midline of back (to the coastal angle) and to epaxial(intrinsic) muscle innverated by posterior ramus |
| Sclerotome resegmentation | Sclerotome is resegnmented into upper and lower part, which then migrate to adjacent to allow nerve fiber transmission proces |
| what does sclerotomal mesenchyme give rise to? | Vertebrae and Rib Sclerotomal mesenchyme ==> cartilage ==> bone |
| disease when spinous process is not form? | Spina bifida |
| Name possible clinical disease associate with spina bifida | 1) spina bifida occulta 2) meningocele (surgically removed) 3) meningomyelocele 4) Rachischisis (usually fatal) |
| After formation of vertebrate, what does notochord become? | Nucleus pulposus |
| Which segment does T12 most assoicate with? | Lower lumbar spinal cord segment |
| Which segment does L1 most assoicate with? | All sacral spinal cord segment |