BIO202-CH16-Thyroid Word Scramble
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Question | Answer |
What is often referred to as body's major metabolic hormone? | TH - thyroid hormone |
__ affects virtually every cell in the body. | TH - by stimulating a calorigenic effect |
T1,T2, T3, & T4 differ from each other in what way? | The number of iodine attached to tyrosine. |
Most T3 is generated in __. | Peripheral tissues |
The inital response to TSH bonding is __. | Secretion of thyroid hormone. |
What is synthesized to "restock" follicle lumen? | Colloid |
Why is thyroid gland unique? | Ability to store its hormone extracellularly & in large quantities. |
Most released T4 & T3 immediately bind to __. | TBGs (thyroxine-binding globulins) - transport proteins produced by liver. |
TH enters target cell & binds to __. | intracellular receptors in nucleus - initiates mRNA transcription. |
Hypothyroid syndrome is called __. | myxedema |
What are the symptoms of myxedema? | Low metabolic rate, edema, lethargy & mental sluggishness |
Endemic goiter caused by? | Enlarged thyroid due to lack of iodine. Follicle cells produce colloid but cannot iodinate it. |
Hypothyroidism in children in called __. | Cretinism - developmental abnormalities & mental retardation. |
What is Graves' disease? | Hyperthyroid - autoimmune disease - protrusion of eyeballs & elevated metabolic rate. |
Calcitonin is? | Hormone produced by parafollicular (C) cells of thyroid gland - lowers blood Ca2+ |
What effect does calcitonin have? | Lower blood Ca2+ levels - targets skeleton & inhibits osteoclast activity |
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