Derm Systemic 2 Word Scramble
|
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Question | Answer |
the hallmark of vasculitis | palpable purpura |
well defined raised petechiae and macules, may have a central area of hemorrhage, can become confluent, primarily on lower extremities but can extend to buttocks. can become ulcerative, necrotic in severe cases. Associated with vasculitis | palpable purpura |
cutaneous disorders associated with diabetes | acanthosis nigricans, diabetic dermaopathy, diabetic bullae, necrobiosis lipoidica, infections, lesions secondary to peripheral neuropathy, lesions secondary to peripheral vascular disease |
skin infections associated with diabetes | abscesses, furuncles, and carbuncles, cellulitis, erythrasma, candidiasis, malignant otitis externa, mucormycosis |
thickened hyperpigmented velvety plaques that develop on neck, axillae, other body folds. associated with obesity and insulin resistance | acanthosis nigricans |
Most common cutaneous manifestation of DM: | diabetic dermopathy (incidence 10-60%) |
Characterized by atrophic, small (<1 cm), brown lesions on lower extremities (2/2 microangiopathy) = | diabetic dermopathy |
appear spontaneously, usually on hands or feet, patho-unclear but they appear to be associated with peripheral neuropathy in diabetics | diabetic bullae |
three types of diabetic bullae | sterile (heals w/o scarring), hemorrhagic (heals with scarring), non-scarring (triggered by sun exposure) |
flesh colored or reddish brown papules that evolve into waxy plaques (center becomes yellow and atrophic, telangiectasis my appear, mostly seen on shins usually bilateral) | Necrobiosis Lipodica Diabeticorum |
pathophysiology of necrobiosis lipodica diabeticorum | degeneration of collegen in dermis and subutaneous fat |
treatment for necrobiosis lipodica diabeticorum | topical or intralesional steroid |
can result from neuropathic or ischemic causes from diabetes. often surrounded by callus formation, may extend through subcutaneous tissue to bone-->osteomyelitis | diabetic ulcers |
thickened hyperpigmented velvety plaques that develop on neck, axillae, other body folds; assoc w/obesity and insulin resistance | acanthosis nigricans |
appear spontaneously, usually on hands or feet, patho-unclear but they appear to be associated with peripheral neuropathy in diabetics | diabetic bullae |
three types of diabetic bullae | sterile (heals w/o scarring), hemorrhagic (heals with scarring), non-scarring (triggered by sun exposure) |
reddish brown papules, evolve into waxy plaques (center becomes yellow and atrophic, telangiectasis appear, seen on shins usually bilateral) | Necrobiosis Lipodica Diabeticorum |
2/2 neuropathic / ischemic causes from DM; often surrounded by callus formation, may extend thru subQ tissue to bone => osteomyelitis | diabetic ulcers |
uncommon benign skin disorders of papules and plaques in annular distribution, self limiting (more common in women, hands, feet, knees and elbows) usually associated with diabetes | granuloma annulare |
yellow plaques occuring near medial canthus of eyelid, upperlid>lower lid (50% associated with elevated lipid levels) | xanthelasma |
Pruritic raised erythematous plaques | Urticaria |
localized swelling of skin & mucous membranes w/pruritis; usually resolve in 24 hr, may last up to 6 weeks; | urticaria |
Urticaria triggers: | foods, drugs, infxn (viral hep, mono), stress, latex, environmental (sun, bugs) |
urticaria that extends into subcutaneous tissues | angioedema |
urticaria >6 wks duration; trigger is undetermined in 85% of cases; (poss 2/2 autoimmune or chronic dz) | chronic urticaria |
wheal is the characteristic lesion of | urticaria |
edematous papule or plaque, transient, very pruritic | wheal (urticaria) |
treatment of urticaria | Remove cause if possible; H-1 and H-2 blockers have synergistic effect, doxepin, glucocorticoids, epinephrine |
clinical evaluation of chronic urticaria | complete H&P, CBC, LFT's, TFT's, RFT's, ESR or CRP, biopsy in cases of vasculitis (referral to allergist/rheumatologist may be appropriate) |
treatment principles of chronic urticaria | avoid use of systemic corticosteroids, identify exacerbating/causative factors, around the clock use of antihistamines |
urticaria: tx: H1 blockers efficacy: | 1st gen H1 (Benadryl, hydroxyzine, Allegra, Zyrtec) better in acute urticaria; 2d gen H1 (famotidine, cimetidine)better in chronic |
urticaria/angioedema most common when | 3rd-4th decade |
necrobiosis (NLD) incidence: | 2% of diabetics; female > male |
Erythema nodosum: epi | 18-30 year olds; F>M; poss assoc w/leukemia |
Erythema nodosum: lesion | large erythematous (subQ), firm, hard nodules, LE; very painful |
Hx URI then palpable purpuric rash to buttocks, posterior thighs | HSP (Hx post Strep A infection) |
Created by:
Abarnard
Popular Medical sets