Asthma- Jackson Word Scramble
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Question | Answer |
Define Asthma | A chronic, common, persistent inflammatory disease of the airways characterized by reversible airway obstruction, airway inflammation, airway hyperresponsiveness and airway remodeling |
Extrinsic (or Atopic asthma) key characteristics | Develops early in life, allergy coexists, family history of atopy, attacks associated with seasonal allergies, Total serum IgE is elevated |
Intrisic (or Idiopathic asthma) key characteristics | Appears later in life, not associated with allergy or IgE, Blood and sputum eosinophilia, less common than atopic |
Nonspecific Asthma triggers | Infections, Physiologic factors (exercise, hyperventilation, deep breathing), atmospheric factors, Ingestants, Laughter |
Signs of acute asthma | Cough, Tachypnea, Wheezing (most often in expiration), Use of accessory muscles of respiration, rapid pulse, lung fields are hyperresonant |
An atopic asthmatic has more of a ___ response than normal | Th2 |
Contributors to inflammatory response in asthmatic | Increased mucous production, basement membrane thickening, angiogenesis, lamina propria thickens, Vagal stimulation |
Which factor stimulates Mast cells | IgE |
Which factor is most long acting in asthma bronchoconstriction and therefor a target of some drugs | Leukotriens |
What do chemotactic factors and cell adhesion molecules do in asthma? | Set up a gradient to increase cell mobility of inflammatory cell infiltration |
IL stimulated by the Th2 produce | IgE |
Mucous plugging | Excessive mucous in asthma that can lead to death |
Histamine | Causes early vasodilation and brochoconstriction, very transient, released from mast cells |
Asthma patient management | Objective measure of lung function, avoid triggers, drug therapy, education, plan for managing exacerbation, provide follow-up care, OMT |
Created by:
mcasto
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