AP2 LC3
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| Major function of the immune system | Recognize between self and non-self
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| Guard against a broad range of pathogens and their effectiveness does not depend on prior exposure. Includes 1st line of defense(external surface membranes) and 2nd line of defense (inflammation, complement, cells, etc). | Non-specific Resistance
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| This is the 3rd line of defense. Two types: Humoral & Cell Mediated | Specific Immunity
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| Responsibility of B cells; produce antibodies that bind to antigens and tag for destruction | Humoral Immunity
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| Responsibility of T cells; directly attach and destroy foreign cells | Cell-mediated Immunity
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| Molecule that triggers an immune response | Antigen
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| MCH is a ___ antigen | Self antigen
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| Proteins which are found on the surface of cells and look like hotdog buns | MCH
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| Found on all nucleated cells, produced by cell and transported to plasma membrane. Picks up peptides along the way. If peptides are self, immune system leaves it alone. If non self, triggers immune response. | MCH-1
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| Found only on APC's to display only foreign antigens | MCH-2
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| Bacteria, viruses, etc. that can mobilize the immune system and provoke a response. | Non Self Antigen
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| Certain regions of an antigen molecule that stimule an immune response. One antigen have several different types of these. | Epitopes
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| Ability to stimulate proliferation of specific lymphocytes and antibodies. | Immunogenicty
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| Ability to react with products of immunogenicty (; lymphocytes and antibodies) | Reactivity
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| Body makes own antibodies or T cells against pathogen | Active Immunity
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| Body acquires antibodies from another person or animal that has developed its own immunity to the pathogen (borrowed) | Passive Immunity
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| Body makes it own immunity | Naturally Acquired
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| Induced artificially through vaccinations or immune serums | Artificially Acquired
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| Reaction to vascular tissue to injury | Inflammation
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| Proteins that circulate in the blood in inactive form and are activated in the presence of pathogens | Complement
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| Antiviral proteins that alert neighboring cells and protect them from being infected | Interferon
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| This cell kills bacteria in the connective tissue by phagocytosis and respiratory burst | Neutrophils
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| This cell stand guard against parasites, allergens and other pathogens | Eosinophils
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| Any cell of the body, other than a leukocyte, that is specialized for phagocytosis | Macrophage
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| This cell can kill cancer cells and virus-infected cells. Does not depend on recognition or specific antigen but detect lack of self cell receptors Do not exhibit memory repsonse and are non-phagocytic Secrete inflammatory chemicals and perforin | Natural Killer cells
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