a&p2 exam 2
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| IgM | circulate throughout body; present during first response
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| IgG | cross blood vessels; protect against bacteria viruses and toxins in blood; trigger complement system
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| IgA | in mucous membranes, tears and saliva; prevent attachment of bacteria and viruses to epithelial surfaces
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| IgD | on external membranes of B cells; initiates B cell differentiation
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| IgE | attaches to receptors on mast cells and basophils; stimulates releases of histamines and other chemicals that cause allergic reaction
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| what is the antibody effector mechanism 'neutralization' | blocks viral attachment sites, coats bacterial toxin
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| perforin | an antimicrobial protein that puts holes in the plasma membrane of a microbe to lyse it
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| pyrogens | released by leukocytes & cause fever (prostaglandin), inhibit bacterial growth because the body has a fever
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| interferons | released into interstitial space to diffuse to neighboring cells to promote production of antiviral proteins to stop reproduction of the viral genome; nonspecific
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| MHC I surface protein | sends out antigen signals, making the cell an APC; only nucleated cells
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| what is opsinization | an antibody effector mechanism; bound antibodies enhance macrophage attachment to and phagocytosis of microbes
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| MHC II surface protein | allow helper T cells to interact/bind with antigen; ONLY found in macrophages, B cells, and activated T cells
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| cytotoxic T cell | detects an APC and disrupts the plasma membrane to kill the cell; undergoes division to make memory cell
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| B cells | humoral response; form and mature in bone marrow; only activated when near antigen; undergo colonial division to make plasma cells and memory cells
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