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a&p2 exam 2
Question | Answer |
---|---|
IgM | circulate throughout body; present during first response |
IgG | cross blood vessels; protect against bacteria viruses and toxins in blood; trigger complement system |
IgA | in mucous membranes, tears and saliva; prevent attachment of bacteria and viruses to epithelial surfaces |
IgD | on external membranes of B cells; initiates B cell differentiation |
IgE | attaches to receptors on mast cells and basophils; stimulates releases of histamines and other chemicals that cause allergic reaction |
what is the antibody effector mechanism 'neutralization' | blocks viral attachment sites, coats bacterial toxin |
perforin | an antimicrobial protein that puts holes in the plasma membrane of a microbe to lyse it |
pyrogens | released by leukocytes & cause fever (prostaglandin), inhibit bacterial growth because the body has a fever |
interferons | released into interstitial space to diffuse to neighboring cells to promote production of antiviral proteins to stop reproduction of the viral genome; nonspecific |
MHC I surface protein | sends out antigen signals, making the cell an APC; only nucleated cells |
what is opsinization | an antibody effector mechanism; bound antibodies enhance macrophage attachment to and phagocytosis of microbes |
MHC II surface protein | allow helper T cells to interact/bind with antigen; ONLY found in macrophages, B cells, and activated T cells |
cytotoxic T cell | detects an APC and disrupts the plasma membrane to kill the cell; undergoes division to make memory cell |
B cells | humoral response; form and mature in bone marrow; only activated when near antigen; undergo colonial division to make plasma cells and memory cells |