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a&p2 exam 2

IgM circulate throughout body; present during first response
IgG cross blood vessels; protect against bacteria viruses and toxins in blood; trigger complement system
IgA in mucous membranes, tears and saliva; prevent attachment of bacteria and viruses to epithelial surfaces
IgD on external membranes of B cells; initiates B cell differentiation
IgE attaches to receptors on mast cells and basophils; stimulates releases of histamines and other chemicals that cause allergic reaction
what is the antibody effector mechanism 'neutralization' blocks viral attachment sites, coats bacterial toxin
perforin an antimicrobial protein that puts holes in the plasma membrane of a microbe to lyse it
pyrogens released by leukocytes & cause fever (prostaglandin), inhibit bacterial growth because the body has a fever
interferons released into interstitial space to diffuse to neighboring cells to promote production of antiviral proteins to stop reproduction of the viral genome; nonspecific
MHC I surface protein sends out antigen signals, making the cell an APC; only nucleated cells
what is opsinization an antibody effector mechanism; bound antibodies enhance macrophage attachment to and phagocytosis of microbes
MHC II surface protein allow helper T cells to interact/bind with antigen; ONLY found in macrophages, B cells, and activated T cells
cytotoxic T cell detects an APC and disrupts the plasma membrane to kill the cell; undergoes division to make memory cell
B cells humoral response; form and mature in bone marrow; only activated when near antigen; undergo colonial division to make plasma cells and memory cells
Created by: aahenderson9



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