Busy. Please wait.
Log in with Clever
or

show password
Forgot Password?

Don't have an account?  Sign up 
Sign up using Clever
or

Username is available taken
show password

Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.

Respiratory System

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
        Help!  

Question
Answer
show pulmonary ventilation  
🗑
period when air flows into lungs   show
🗑
period when gases exit lungs   show
🗑
show relative to  
🗑
show atmospheric pressure (Patm)  
🗑
at __ __ Patm is 760 mm Hg   show
🗑
show atmospheric units  
🗑
show lower than  
🗑
show higher than  
🗑
is equal to atmospheric pressure   show
🗑
show intrapulmonary pressure (Ppul)  
🗑
show intraplueral pressure (Pip)  
🗑
Pip is always __ relative to Ppul   show
🗑
lung's natural tendency to __ always assume smallest possible size   show
🗑
show attract  
🗑
show surface tension of alveolar fluid  
🗑
show lung-collapsing forces  
🗑
force that tends to pull thorax outward & to enlarge lungs   show
🗑
show pleural fluid  
🗑
pleurae slide from side to side easily, but remain closely __   show
🗑
separating the pleurae requires __ force   show
🗑
net result of dynamic interplay btwn forces of pleurae is a(n) __ __   show
🗑
show minimal  
🗑
show lymphatics  
🗑
show positive pressure  
🗑
any condition that __ Pip with intrapulmonary pressure causes immediate lungs collapse   show
🗑
difference btwn intrapulmonary & intrapleural pressures (Ppul - Pip)   show
🗑
transpulmonary pressure keeps __ __ of lungs open or keeps them from collapsing   show
🗑
determines size of lungs at any given time   show
🗑
the __ the transpulmonary pressure, the larger the lungs   show
🗑
show atelectasis  
🗑
show associated alveoli  
🗑
show chest wound  
🗑
presence of air i pleural cavity is referred to as   show
🗑
show reversed  
🗑
show lungs are in separate cavities  
🗑
pulmonary ventilation, consisting of inspiration & expiration, is a(n) __ __ that depends on volume change in thoaric cavity   show
🗑
show volume changes  
🗑
show pressure changes  
🗑
show pressure; volume  
🗑
states that when temperature is constant, pressure of a gas varies inversely with its volume   show
🗑
formula; at constant temperature, pressure of a gas varies inversely with its volume   show
🗑
show fill  
🗑
show far apart  
🗑
show closer together  
🗑
show thoracic cavity  
🗑
volume of thoracic cavity is __   show
🗑
show decreasing gas pressure inside  
🗑
drop in pressure within thoracic cavity causes   show
🗑
show flow down  
🗑
show inspiratory muscles  
🗑
during normal __ __ the inspiratory muscles are activated   show
🗑
show superior-inferior dimension  
🗑
show quiet inspiration  
🗑
__ __ external intercostal muscles lifts rib cage & pulls sternum superiorly   show
🗑
show obliquely downward  
🗑
when ribs are raised & drawn together, they swing outward, expanding __ of thorax both laterally & in anteroposterior plane   show
🗑
action of diaphragm & external intercostal muscles expand thoracic dimensions only a few __ along each plane, enough to increase thoracic volume by almost 500 ml   show
🗑
usual amount of air that enters lungs during normal quiet inspiration   show
🗑
show the diaphragm  
🗑
show during inspiration  
🗑
inspiratory muscles contract--> thoracic cavity volume increases --> lungs are stretched & intrapulmonary volume increases --> intrapulmonary pressure drops to -1mm Hg --> air flows into lungs down pressure gradient until intrapulmonary pressure is zero   show
🗑
inspiratory muscles relax --> thoracic cavity volume decreases --> elastic lungs recoil passively & intrapulmonary volume decreases --> intrapulmonary pressure rises to +1 mm Hg --> air flows out of lungs down its pressure gradient until Pip is zero   show
🗑
show air rushes into lungs along pressure gradient  
🗑
show Ppul = Patm  
🗑
show deep/forced  
🗑
scalenes & sternocleidomastoid muscles of neck & pectoralis minor of chest __ __ even more than occurs during quiet inspiration   show
🗑
back extends as thoracic curvature is __ by erector spinae muscles during quiet inspiration   show
🗑
show quiet expiration  
🗑
during quiet expiration, as inspiratory muscles relax & resume their __ __, the rib cage descends & lungs recoil   show
🗑
both thoracic & intrapulmonary volumes decrease   show
🗑
volume decreasing during quiet expiration __ the alveoli & Ppul rises to about 1mm Hg above atmospheric pressure   show
🗑
when Ppul > Patm the pressure gradient __ __ to flow out of the lungs   show
🗑
active process produced by contraction of abdominal wall muscles, primarily the oblique & transverse muscles   show
🗑
show intra-abdominal  
🗑
show depresses  
🗑
internal intercostal muscles also help to depress the rib cage &   show
🗑
show precise regulation  
🗑
inspiratory muscles consume energy to   show
🗑
show friction/drag  
🗑
show equivalent  
🗑
amount of gas flowing into & out of the alveoli is directly proportional to (triangle)P, which is the difference in pressure/pressure gradient between   show
🗑
show large changes  
🗑
during normal quiet breathing is 2 mm Hg/less; is sufficient to move 500 ml of air in/out of lungs with each breath   show
🗑
gas flow changes __, gas flow decreases as resistance increases   show
🗑
resistance in respiratory tree is determine mostly by the diameters of __ __   show
🗑
show low viscosity of air  
🗑
as a rule, airway resistance is insignificant because as airways get progressively smaller, there are progressively more branches; as result, although individual bronchioles are tiny there are enormous number of them in parallel, so   show
🗑
show medium-sized bronchi  
🗑
at terminal bronchioles, gas flow stops & __ takes over as main force driving gas movement, so resistance is no longer an issue   show
🗑
local accumulations of mucus, infectious material, or solid tumors   show
🗑
show more strenuous  
🗑
when bronchioles are severely constricted/obstructed even most magnificent respiratory efforts cannot __ __ to life-sustaining levels   show
🗑
show gas-liquid boundary  
🗑
show surface tension  
🗑
show dissimilar  
🗑
surface tension __ any force that tends to increase surface are of the liquid   show
🗑
show highly polar  
🗑
water has a very __ surface tension   show
🗑
show reduce alveoli  
🗑
show pure water  
🗑
secretion produced by certain cells of alveoli that reduces surface tension of water molecules, thus preventing collapse of the alveoli after each expiration   show
🗑
show detergent-like complex  
🗑
surfactant decreases __ of water molecules   show
🗑
surfactant reduces surface tension of alveolar fluid, so __ __ is needed to overcome those forces to expand lungs & discourage alveolar collapse   show
🗑
breaths that are deeper than normal stimulate type II cells to   show
🗑
show too little  
🗑
condition peculiar to premature babies; inadequate pulmonary surfactant is produced due to prematurity often they are unable to keep alveoli inflated btwn breaths   show
🗑
show IRDS  
🗑
device that maintain positive airway pressure throughout respiratory cycle, for premature babies, are often used to   show
🗑
show bronchopulmonary dysplasia  
🗑
show lung compliance (CL)  
🗑
the more a lung expands for a given rise in transpulmonary pressure, the __ its compliance   show
🗑
the higher the lung compliance, the easier it is to __ __ at any given transpulmonary pressure   show
🗑
lung compliance is determined by __ of the lung tissue   show
🗑
show alveolar  
🗑
show high  
🗑
show kept low  
🗑
because of high lung distensibility & low alveolar surface tension, lungs of healthy people tend to have __ __ __, which favors efficient ventilation   show
🗑
lung compliance is diminished by decrease in __ __ of lungs   show
🗑
show nonelastic scar  
🗑
show fibrosis  
🗑
show compliance of thoracic wall  
🗑
show hinder  
🗑
total compliance of respiratory system is comprised of   show
🗑
show total respiratory compliance  
🗑
show respiratory capacities  
🗑
air moving into & out of the lungs with each breath; about 500 ml   show
🗑
amount of air that can be inspired forcibly beyond the tidal volume; 2100-3200 ml   show
🗑
show expiratory reserve volume (ERV)  
🗑
1200 ml of air that remains in the lungs, which helps to keep alveoli patent & prevent lung collapse   show
🗑
include inspiratory capacity, functional residual capacity, vital capacity, & total lung capacity; always consist of 2< lung volumes   show
🗑
total amount of air that can be inspired after a tidal expiration; sum of TV & IRV   show
🗑
show functional residual capacity  
🗑
show vital capacity (VC)  
🗑
show total lung capacity (TLC)  
🗑
lung volumes & capacities, with exception of __ __, tend to be smaller in women than in men   show
🗑
show anatomical dead space  
🗑
show ideal body weight  
🗑
if TV is 500 ml, only 350 ml of it is involved in alveolar ventilation, leaving 150 ml of tidal breath   show
🗑
alveoli cease to act in gas exchange due to alveolar collapse or obstruction by mucus creates   show
🗑
alveolar dead space is added to anatomical dead space, and sum of nonuseful volumes is referred to as   show
🗑
original instrument for measuring the volume of air entering and leaving the lungs   show
🗑
spirometer is most useful in evaluating losses in respiratory function & following course of certain __ __   show
🗑
involves increased airway resistance   show
🗑
involves reduction in total lung capacity resulting from structural or functional changes in lungs   show
🗑
increases in TLC, FRC, & RV may occur as a result of __ of lungs in obstructive disease   show
🗑
VC, TLC, FRC, & RV are __ in restrictive pulmonary disorders which limit lung expansion   show
🗑
total amount of gas that flows into or out of respiratory tract in 1 minute   show
🗑
during normal quiet breathing the minute ventilation in healthy people is about   show
🗑
show 200 L/min  
🗑
show forced vital capacity (FVC)  
🗑
determined amount of air expelled during specific time intervals of FVC test   show
🗑
show exhale  
🗑
show alveolar ventilation rate (AVR)  
🗑
takes into account volume of air wasted in dead space & measures flow of fresh gases in/out of alveoli during particular time interval   show
🗑
formula for AVR   show
🗑
show 4200 ml/min  
🗑
show raising respiratory rate  
🗑
show never reaches exchange sites  
🗑
as tidal volume approaches the dead space value, __ __ approaches zero regardless of how fast a person is breathing   show
🗑
show nonrespiratory air movements  
🗑
states that total pressure exerted by mixture of gases is sum of pressures exerted independently by each gas in mixture; pressure exerted by each gas is directly proportional to percentage of that gas in gas mixture   show
🗑
pressure exerted by each gas   show
🗑
make up about 79% of air   show
🗑
show partial pressure of nitrogen (Pn2)  
🗑
20.9% x 760 mm Hg) 159 mm Hg   show
🗑
show nitrogen & oxygen together  
🗑
show air  
🗑
show decline  
🗑
show high altitudes  
🗑
show descent below sea level  
🗑
show Henry's law  
🗑
according to Henry's law the greater the concentration of particular gas in gas phase, the more & faster that gas will go into   show
🗑
show equilibrium  
🗑
if partial pressure of gas later becomes greater in liquid than in adjacent gas phase, some of dissolved gas molecules will   show
🗑
show solubility; temperature  
🗑
show carbon dioxide  
🗑
only 1/20 as soluble in air as carbon dioxide   show
🗑
show nitrogen  
🗑
at a given partial pressure much more CO2 than O2   show
🗑
show goes into solution  
🗑
show decrease gas solubility  
🗑
provide clinical applications of Henry's law; contain O2 gas at pressures higher than 1 atm & are used to force greater-than-normal amount of O2 into blood of patients suffering from carbon monoxide poisoning or tissue damage following radiation therapy   show
🗑
used to treat individuals with gas gangrene, because anaerobic bacteria causing infection cannot live in presence of high O2 levels   show
🗑
show "the bends"  
🗑
develops rapidly when Po2 is greater than 2.5-3 atm; excessively high concentrations generate huge amounts of harmful free radicals, resulting in profound CNS disturbances, coma, & death   show
🗑
show gas exchange  
🗑
show humidification  
🗑
difference in atmospheric & alveoli gases reflect effects of the __ __ alveolar gas that occurs with each breath   show
🗑
because only 500 ml of air is inspired with each tidal inspiration, gas in alveoli is actually a mixture of newly inspired gases and   show
🗑
alveolar partial pressures of O2 & CO2 are easily changed by increasing breathing __ & __   show
🗑
high AVR bring more O2 into the alveoli, increasing alveolar Po2, and rapidly   show
🗑
show external respiration  
🗑
color change of blood during pulmonary gas exchange is due to O2 __ & __ to hemoglobin in RBCs   show
🗑
partial pressure __ & gas __ influence movement of oxygen & carbon dioxide across respiratory membrane   show
🗑
matching of __ ventilation & __ blood perfusion influence movement of oxygen & carbon dioxide across respiratory membrane   show
🗑
show structural  
🗑
show partial pressure gradients of O2 & CO2  
🗑
show steep oxygen partial pressure gradient  
🗑
show diffuses rapidly  
🗑
show equilibrium  
🗑
show pulmonary capillaries  
🗑
show opposite direction  
🗑
equal amounts of CO2 & O2 are exchanged, even with O2 having steeper pressure gradient, because CO2 is 20x more soluble in   show
🗑
amount of gas reaching alveoli   show
🗑
show perfusion  
🗑
for gas exchange to be __ there must be a coupling between ventilation & perfusion   show
🗑
show redirected  
🗑
show maximal  
🗑
__ mechanisms controlling pulmonary vascular muscle is the opposite of mechanism controlling most arterioles in systemic circulation   show
🗑
as result of changing diameter of local bronchioles and arterioles, alveolar ventilation & pulmonary perfusion are __   show
🗑
show arterioles  
🗑
show bronchioles  
🗑
show dilate  
🗑
results in low O2 & high CO2 levels in alveoli   show
🗑
show physiological match  
🗑
show flushing of blood  
🗑
homeostatic mechanisms that provide appropriate conditions for efficient gas exchange never completely balance ventilation & perfusion because gravity causes __ __ in blood & air flow in lungs   show
🗑
show unventilated areas  
🗑
homeostatic mechanisms that provide appropriate conditions for efficient gas exchange never completely balance ventilation & perfusion because of __ of blood from bronchial veins   show
🗑
in healthy lungs, __ __ is only 0.5-1 micrometer thick, and gas exchange is usually very efficient   show
🗑
show effective thickness  
🗑
greater the surface are of respiratory membrane, the __ __ can diffuse across it in a given period of time   show
🗑
alveolar surface area actually functioning in gas exchange is drastically reduced; walls of adajacent alveoli break down & alveolar chambers become larger in   show
🗑
show identical to those acting in lungs  
🗑
show O2 moves rapidly from blood into tissues until equilibrium is reached  
🗑
venous blood draining to tissue capillary beds & returning to heart has   show
🗑
gas exchanges that occur btwn blood & alveoli & btwn blood & tissue cells take place by __ __ driven by partial pressure gradient of O2 & CO2 that exists on opposite sides of exchange membranes   show
🗑
molecular oxygen is carried to blood bound to   show
🗑
molecular oxygen is carried to blood   show
🗑
composed of 4 polypeptide chains, each bound to an iron-containing heme group   show
🗑
show iron atoms  
🗑
hemoglobin-oxygen combination   show
🗑
show reduced hemoglobin/deoxyhemoglobin (HHb)  
🗑
show fully saturated  
🗑
when 1, 2, or 3 oxygen molecules are bound, hemoglobin is   show
🗑
binding strength   show
🗑
show oxygen saturation  
🗑
show regulated by  
🗑
relationship between degree of hemoglobin saturation & Po2 of blood is not linear because affinity of hemoglobin for O2 changes with   show
🗑
S-shaped curve has steep slope for Po2 values between 10-50 mm Hg and then flattens out between 70-100 mm Hg   show
🗑
Under __ __ conditions aterial blood hemoglobin is 98% saturated and 100 ml of systemic aterial blood contains about 20 ml of O2 (20 vol %)   show
🗑
show plasma  
🗑
show good index  
🗑
when arterial Po2 is significantly less than alveolar Po2 some degree of __ __ exists   show
🗑
as arterial blood flows through systemic capillaries, about 5 ml of O2 per 100 ml of blood is released, yielding an Hb saturation of 75% and O2 content of 15 vol % in   show
🗑
show both alveolar & arterial blood Po2  
🗑
nearly complete saturation of Hb in arterial blood explains why breathing deeply causes very little increase in   show
🗑
Po2 measurements indicate only the amount of __ __ in plasma   show
🗑
show almost completely; O2 binding  
🗑
show steep portion of curve  
🗑
adaptive value of oxygen-hemoglobin dissociation curve is that O2 loading & delivery to tissues can still be adequate when   show
🗑
show at higher altitudes & with cardiopulmonary disease  
🗑
small drop in Po2 will cause large increase in __ in oxygen-hemoglobin dissociation curve   show
🗑
show systemic circuit  
🗑
substantial amounts of O2 are __ __ in venous blood, even though only 20-25% of bound oxygen is unloaded during 1 systemic circuit   show
🗑
amounts of O2 are still available in venous blood, even though only 20-25% of bound oxygen is unloaded during 1 systemic circuit   show
🗑
if O2 drops to very low levels in tissues, such as during vigorous exercise, much more O2 will dissociate from hemoglobin to be used by tissue cells without any   show
🗑
show influence hemoglobin  
🗑
show 2,3-bisphosphoglycerate (BPG)  
🗑
anaerobic process of glucose breakdown   show
🗑
temperature, blood pH, Pco2, & amount of BPG in blood influence __ __ by modifying three-dimensional structure, thereby changing its affinity for O2   show
🗑
show oxygen unloading from blood  
🗑
decrease in temperature, blood pH, Pco2, & amount of BPG in blood increases __ __ for oxygen, decreasing oxygen unloading   show
🗑
show left  
🗑
increase in temperature, blood pH, Pco2, & amount of BPG in blood shift oxygen-hemoglobin dissociation curve to the __   show
🗑
temperature, blood pH, Pco2, & amount of BPG in blood all tend to be at __ __ in systemic capillaries where oxygen unloading is goal   show
🗑
as cells metabolize glucose & use O2 they release CO2, which increases Pco2 & H+ levels in   show
🗑
declining blood pH   show
🗑
show Hb-O2 bond  
🗑
show Bohr effect  
🗑
show RBC metabolism & BPG synthesis  
🗑
temperature, blood pH, Pco2, & amount of BPG in blood all see to it that Hb unloads much more O2 in vicinity of   show
🗑
show hypoxia  
🗑
show fair-skinned  
🗑
in __ people, when Hb saturation falls below 75% this color change (cyanosis) can only be observed in their mucosae & nail beds   show
🗑
reflects poor O2 delivery resulting from too few RBCs or from RBCs that contain abnormal/too little Hb   show
🗑
show ischemic/stagnant hypoxia  
🗑
occurs when body cells are unable to use O2 even though adequate amounts are delivered; this is consequence of metabolic poisons, such as cyanide   show
🗑
show hypoxemic hypoxia  
🗑
unique type of hypoxemic hypoxia, leading cause of death from fire; does not produce characteristic signs of hypoxia, instead victim is confused & has throbbing headache   show
🗑
cyanosis & resulting respiratory distress   show
🗑
patients with __ __ are given hyperbaric therapy or 100% O2 until it has been cleared from body   show
🗑
normally active body cells produce about 200ml of __ exactly the amount excreted by lungs   show
🗑
show plasma  
🗑
show chemically bound  
🗑
when blood transports CO2 from tissue cells to lungs chemically bound to hemoglobin in RBCs as   show
🗑
show carbaminohemoglobin  
🗑
creation reaction to carbaminohemoglobin is rapid & does not require a(n) __   show
🗑
show amino acids of globin  
🗑
CO2 loading/unloading to & from Hb are directly influenced by   show
🗑
show rapidly dissociates  
🗑
show tissues  
🗑
deoxygenated hemoglobin combines __ __ with CO2 than does oxygenated hemoglobin   show
🗑
blood transports CO2 from tissue cells to lungs as __ __ in plasma   show
🗑
show carbonic acid (H2CO3)  
🗑
carbonic acid (H2CO3) is unstable & __ into hydrogen ions & bicarbonate ions   show
🗑
enzyme that facilitates combination of carbon dioxide with water to form carbonic acid, reversibly catalyzing the conversion of water & CO2 to to carbonic acid   show
🗑
show faster  
🗑
show enhances  
🗑
because of __ __ of Hb, the liberated H+ causes little change in pH under resting conditions   show
🗑
once generated HCO3- __ __ from RBCs into plasma, where it is carried to lungs   show
🗑
process which occurs in cardiovascular system & refers to exchange (facilitated diffusion) of bicarbonate (HCO3-) & chloride (Cl-) across membrane of RBCs   show
🗑
chloride shift is also called   show
🗑
show reversed  
🗑
as blood moves through pulmonary capillaries its Pco2 declines from 45 mm Hg to 40 mm Hg; CO2 must 1st be freed from its __ __   show
🗑
show CO2 & water  
🗑
show markedly affected  
🗑
show CO2 can be carried in blood  
🗑
Haldane effect reflects greater ability of __ __ to form carbaminohemoglobin & to buffer H+ by combining with it; as CO2 enters systemic bloodstream it causes Bohr effect   show
🗑
deoxygenation of the blood increases its ability to carry carbon dioxide & combine with Hb   show
🗑
show tissues & lungs  
🗑
part of blood's carbonic acid-bicarbonate buffer system   show
🗑
typically the H+ released during __ __ __ is buffered by Hb or other proteins within RBCs or plasma   show
🗑
during carbonic acid dissociation, the HCO3- generated in RBCs __ __ __, where it acts as alkaline reserve   show
🗑
show carbonic acid–bicarbonate buffer system  
🗑
show resisting shifts  
🗑
if hydrogen ion concentration in blood begins to rise, __ __ is removed by combining with HCO3- to form carbonic acid   show
🗑
if H+ concentration __ __ desirable levels in blood, carbonic acid dissociates, releasing H+ & lowering blood pH again   show
🗑
show blood pH  
🗑
slow, shallow breathing allows CO2 __ __ in blood, increasing carbonic acid levels & decreasing blood pH   show
🗑
rapid, deep breathing quickly flushes CO2 out of blood, __ carbonic acid levels & increasing blood pH   show
🗑
respiratory ventilation ca provide __ __ to adjust blood pH & Pco2 when it is disturbed by metabolic factors   show
🗑
play major role in acid-base balance of blood   show
🗑
located dorsally near toot of cranial nerve IX   show
🗑
network of neurons that extends in ventral brain stem from spinal cord to pons-medulla junction   show
🗑
clustered neurons in areas of medulla oblongata that are critically important in respiration   show
🗑
show rhythm-generating; integrative  
🗑
show mutual inhibition  
🗑
show phrenic nerves  
🗑
when inspiratory neurons fire in VRG a burst of impulse travels along __ __to excite external intercostal muscles   show
🗑
when VRG's __ __ fire the output stops & expiration occurs passively as inspiratory muscles relax & recoil   show
🗑
show respiratory rate of 12-15 breaths/min  
🗑
cyclic on/off activity of inspiratory & expiratory neurons repeats continuously & inspiratory phase lasts about __ __ followed by expiratory phase lasting about __ __   show
🗑
show eupnea  
🗑
during __ __, VRG networks generate gasping   show
🗑
show stops completely  
🗑
show integrates input  
🗑
influence & modify activity of medullary neurons   show
🗑
show smooth out  
🗑
when lesions are made in pontine respiratory centers' superior region inspirations become __ __   show
🗑
lower pons appears to promote inspiration by stimulation of the I neurons in the medulla oblongata providing a constant stimulus   show
🗑
show pontine respiratory group  
🗑
show periphery  
🗑
show does not abolish breathing  
🗑
normal respiratory rhythm is a result of __ __ of interconnected neuronal networks in medulla   show
🗑
determined by how actively respiratory center stimulates motor neurons serving respiratory muscles   show
🗑
determined by how long inspiratory center is active or how quickly it is switched off   show
🗑
can be modified in response to changing body demands   show
🗑
show excitatory & inhibitory stimuli  
🗑
show chemoreceptors  
🗑
show central chemoreceptors  
🗑
show peripheral chemoreceptors  
🗑
most potent and most closely controlled chemical influencing respiration   show
🗑
show 40 mm Hg  
🗑
show rising CO2 levels have on central chemoreceptors of brain stem  
🗑
high carbon dioxide levels in the blood that accumulates in the brain   show
🗑
as CO2 is accumulated in brain it is __ to form carbonic acid   show
🗑
show liberated; drops  
🗑
when CO2 accumulates in brain, after carbon acid dissociates and H+ is liberated, H+ excites central chemoreceptors which   show
🗑
when H+ excites central chemoreceptors depth & rate of breathing __ __   show
🗑
enhanced alveolar ventilation, when H+ excites central chemoreceptors, quickly flushes   show
🗑
show doubling of alveolar ventilation  
🗑
when Po2 & pH are __ __ the response to elevated Pco2 is even greater   show
🗑
increased ventilation is normally __ ending when homeostatic blood Pco2 levels are restored   show
🗑
even though rising blood CO2 levels act as initial stimulus for increased ventilation, it is rising levels of H+ generated within brain that   show
🗑
__ readily diffuses across blood-brain barrier between brain & blood, but __ does not   show
🗑
control of breathing during rest is aimed primarily at __ __ concentration in the brain   show
🗑
show acute mountain sickness (AMS)  
🗑
show severe cases  
🗑
show acclimatization  
🗑
show hyperventilation  
🗑
low CO2 levels in the blood   show
🗑
when a person hyperventilates (involuntarily) & becomes dizzy/faints, this is due to hypocapnia causing cerebral blood vessels to __ reducing brain perfusion & producing cerebral ischemia   show
🗑
show falling  
🗑
when Pco2 is abnormally low, respiration is __ & becomes slow & shallow   show
🗑
blood O2 content rarely drops much __ __ of normal during regular breath-holding, because as Po2 drops, __ rises enough to make breathing unavoidable   show
🗑
strenuous hyperventilation can lower Pco2 so much that a lag period occurs before it rebounds enough to   show
🗑
show peripheral  
🗑
show aortic bodies  
🗑
show carotid bodies  
🗑
show peripheral chemoreceptors  
🗑
cells sensitive to arterial O2 levels in carotid bodies are   show
🗑
show declining Po2  
🗑
show drop substantially  
🗑
show arterial blood falls below 60 mm Hg  
🗑
once arterial blood falls below 60 mm Hg peripheral chemoreceptors become excited & stimulate respiratory centers to   show
🗑
peripheral chemoreceptors system can __ __ when alveolar O2 levels are low even though brain stem centers are depressed by hypoxia   show
🗑
changes in arterial pH can modify respiratory rate & rhythm even when   show
🗑
because little H+ diffuses from blood into brain, direct effect of arterial H+ concentration on central chemoreceptors is insignificant compared to   show
🗑
show falling arterial pH  
🗑
show compensate; eliminating  
🗑
show most important stimulus  
🗑
low Pco2 levels __ respiration   show
🗑
as CO2 is hydrated in brain tissue, liberated H+ acts directly on central chemoreceptors, causing __ __ in breathing rate & depth   show
🗑
low Po2 __ Pco2 effects   show
🗑
high Po2 levels diminish effectiveness of __ __   show
🗑
both hypocapnia & increase in blood pH __ __   show
🗑
changes in arterial pH resulting from CO2 retention/metabolic factors __ __ through peripheral chemoreceptors to promote changes in ventilation, which in turn modify arterial Pco2 & pH   show
🗑
show respiratory rate & depth  
🗑
sudden chilling of body can cause __ of breathing   show
🗑
show cerebral motor  
🗑
show vagal nerve afferents  
🗑
show lungs are inflated  
🗑
stretch receptors in visceral pleurae & conducting passages in lungs signal the medullary respiratory centers via afferent fibers of __ __   show
🗑
show inflation/Hering-Breuer reflex  
🗑
show protective response  
🗑
show hyperpnea  
🗑
working muscles consume tremendous amounts of O2 & produce large amounts of CO2, so ventilation can increase __ during vigorous exercise   show
🗑
hyperpnea is an increase in ventilation in   show
🗑
show significant changes  
🗑
show low Pco2 & alkalosis  
🗑
show remain constant  
🗑
show psychological  
🗑
abrupt increase in ventilation occurring as exercise begins reflect simultaneous __ __ activation of skeletal muscles & respiratory centers   show
🗑
abrupt increase in ventilation occurring as exercise begins reflect excitatory impulses reaching respiratory centers from __ in moving muscles, tendons, & joints   show
🗑
show O2 deficit  
🗑
rise in lactic acid levels that contributes to O2 deficit during exercise reflects __ __ limitation or inability of skeletal muscles to further increase their oxygen consumption   show
🗑
show chronic obstructive pulmonary disease (COPD)  
🗑
includes emphysema, chronic bronchitisollective term for progressive, obstructive respiratory disorders   show
🗑
show key physiological feature  
🗑
show history of smoking  
🗑
difficult or labored breathing; "air hunger"   show
🗑
common feature of COPDs is that dyspnea occurs and   show
🗑
show respiratory infections  
🗑
most COPD victims develop __ __ manifested as hypoventilation, respiratory acidosis, & hypoxemia   show
🗑
show hypoventilation  
🗑
hypoventilation is insufficient ventilation in relation to __ __ causing CO2 retention   show
🗑
show emphysema  
🗑
show elasticity  
🗑
loss of elasticity in lungs, accompanying emphysema, has consequence of accessory muscles that must be enlisted to breath causing victims to be __ __ because breathing requires 15-20% of total body energy supply   show
🗑
loss of elasticity in lungs, accompanying emphysema, has consequence that when bronchioles open during inspiration they collapse on expiration which causes   show
🗑
show about 5% of total body energy  
🗑
show barrel chest  
🗑
show right ventricle to overwork & become enlarged  
🗑
show hereditary factors, such as alpha-1 antitrypsin deficiency  
🗑
inhaled irritants lead to chronic excessive mucus production by mucosa of lower respiratory passageways & to inflammation & fibrosis of that mucosa; these responses obstruct airways & severely impair lung ventilation & gas exchange   show
🗑
show stagnant pools of mucus  
🗑
in chronic bronchitis the __ __ __ is usually moderate compared to emphysema suffers   show
🗑
show contribute to  
🗑
show pink puffer  
🗑
show blue bloaters  
🗑
hypoxia related to COPD causes constriction of pulmonary blood vessels, which leads to pulmonary hypertension & __ heart failure   show
🗑
show strength of their innate respiratory drive  
🗑
COPD is routinely treated with __ & __ in aerosol form/inhalers   show
🗑
show lung volume reduction surgery  
🗑
show acute respiratory distress  
🗑
in some COPD patients giving pure O2 can increase __ __ & lower blood pH to life-threatening levels, thought to be sudden loss of hypoxic drive   show
🗑
show hypoxic drive hypothesis  
🗑
O2 dilates pulmonary arterioles, increasing perfusion & worsening an already poor __ __, in COPD patients   show
🗑
show underlying COPD  
🗑
characterized by episodes of coughing, dyspnea, wheezing & chest tightness, along or in combination   show
🗑
show acute exacerbation  
🗑
show active inflammation  
🗑
in asthma, airway inflammation is a(n) __ __ under control of Th2 cells, subset of T lymphocytes   show
🗑
show TH2 cells  
🗑
once someone has __ __, inflammation periods even during symptom-free periods & makes airways hypersensitive to almost any irritant   show
🗑
show thickened  
🗑
show inhaled corticosteroids  
🗑
show antileukotrienes & antibodies against the patient's own IgE class of antibodies  
🗑
infectious disease; spread by coughing & primarily enters body in inhaled air   show
🗑
mycobaterium tuberculosis   show
🗑
TB mostly effects lungs but can   show
🗑
show squamous cell carcinoma  
🗑
show adenocarcinoma  
🗑
show small cell carcinoma  
🗑
show ectopic sites  
🗑
show ACTH; ADH  
🗑
small cell carcinomas that secrete ACTH can   show
🗑
small cell carcinomas that secrete ADH can lead to   show
🗑
with lung cancer, __ __ of diseased lung has the greatest potential for prolonging life & providing a cure   show
🗑
show often metastasized  
🗑
in most lung cancer cases radiation therapy & chemotherapy are the __ __, but have low success rates   show
🗑
show new therapies  
🗑
show cancer vaccines  
🗑
new therapies on the horizon include various forms of __ __ to replace defective genes that make tumor cells divide continuously   show
🗑
show cephalocaudal direction  
🗑
head-to-tail   show
🗑
2 thickened plates of ectoderm present on anterior aspect of head by 4th week of development   show
🗑
show olfactory pits  
🗑
show developing pharynx  
🗑
epithelium of lower respiratory organs develops as outpocketing of __ __, which becomes pharyngeal mucosa   show
🗑
show tracheal lining  
🗑
present by 5th week of development; distal part of laryngotracheal bud splits and forms   show
🗑
show endoderm-derived  
🗑
by 28 weeks respiratory system has __ __ to allow baby born prematurely to breathe on its own   show
🗑
babies born before 28 weeks tend to exhibit infant respiratory distress syndrome resulting from   show
🗑
during fetal life lungs are filled with fluid & all respiratory exchanges are made by   show
🗑
cause circulating blood to largely bypass lungs   show
🗑
at birth, fluid-filled pathway empties and respiratory passageways   show
🗑
show take its first breath  
🗑
it is nearly __ __ before newborn's lungs are fully inflated   show
🗑
most common lethal genetic disease in North America, strikes 1/2400 births; causes secretion of abnormally viscous mucus that clogs respiratory passages, providing breading ground for airborne bacteria that predisposes child to respiratory infections   show
🗑
infection of CF victims' lungs with bacterium __ __ trips genetic switch that causes disabled cells to churn our oceans of abnormal mucin, then feeding on stagnant pools of mucus & keep sending signals to cells to make more   show
🗑
in CF, toxins released by bacteria & local inflammatory reaction set up by immune response both   show
🗑
show attack lung tissue  
🗑
show lung transplant  
🗑
show food digestion  
🗑
show cystic fibrosis transmembrane conductance regulator (CFTR) protein  
🗑
show Cl-  
🗑
show amino acid  
🗑
in those with mutated gene, CFTR consequently allows less Cl- to be secreted and less water flows, resulting in   show
🗑
show conventional therapy for CF  
🗑
basic goal of CF research is to restore normal salt/water movements by introducing __ __ genes into respiratory tract mucosa cells   show
🗑
basic goal of CF research is to restore normal salt/water movements by prodding another __ __ to take over duties of transporting Cl-   show
🗑
basic goal of CF research is to restore normal salt/water movements by developing techniques to free CFTR protein   show
🗑
CF antiinflammatory agent being tested is fatty acid found in fish oils   show
🗑
show hypertonic saline droplets  
🗑
respiratory rate is __ in newborns (40-80 respirations/minute)   show
🗑
show around 25/minute  
🗑
show between 12-18/minute  
🗑
show alveoli are present  
🗑
show horizontal course  
🗑
infants relay almost entirely on __ __ __ to increase thoracic volume for inspiration   show
🗑
by 2 years of age ribs are positioned __ __, and adult form of breathing is established   show
🗑
show external factors  
🗑
__ __ respiratory diseases at present at COPD, asthma, lung cancer, & multidrug-resistant TB   show
🗑
show inactive people  
🗑
as we age, thoracic wall becomes __ __ & lungs gradually lose their elasticity   show
🗑
vital capacity declines about 1/3 by   show
🗑
show during sleep  
🗑
show tend to exhibit  
🗑
show sleep apnea  
🗑
functional residual capacity is   show
🗑
inspiratory rate is   show
🗑
show about 500 ml  
🗑
total lung capacity is   show
🗑
vital capacity is   show
🗑
show movement of air into and out of the lungs so that gases are continuously changed and refreshed  
🗑
transport of oxygen from lungs to body cells and carbon dioxide from tissue cells to lungs   show
🗑
show movement of oxygen from the blood to tissue cells and of carbon dioxide from tissue cells to blood  
🗑
external respiration is   show
🗑
show actual site of gas exchange  
🗑
conducting zone is   show
🗑
show Boyle's law  
🗑
show Dalton's law  
🗑
when a mixture of gases is in contact with a liquid, each gas will dissolve in the liquid in proportion to its partial pressure; this affects the movement of oxygen gas from the lungs into fluids in the tissues   show
🗑
nasal cavity   show
🗑
show commonly called the throat; air leaves the nose and enters here en route to the lungs  
🗑
show contains vocal cords that produce speech; called the voice box  
🗑
show descends from the larynx as a single tube reinforced with cartilage rings before it divides to go to each lung  
🗑
show major branches of the cartilage-reinforced tube that go to each lung  
🗑
show terminal branches of the lungs where respiratory gas exchange occurs  
🗑
show inhaled irritants lead to chronic excessive mucus production by the mucosa of the lower respiratory passageways and to inflammation and fibrosis of that mucosa  
🗑
show permanent enlargement of the alveoli, accompanied by deterioration of the alveolar walls  
🗑
show characterized by episodes of coughing, dyspnea, wheezing, and chest tightness; airways become hypersensitive to irritants due to inflammation  
🗑
lung cancer   show
🗑
show lower than outside pressure as diaphragm contracts  
🗑
show pressure change  
🗑
alveolar ventilation rate is movement of air   show
🗑
formula for alveolar ventilation rate is   show
🗑
hemoglobin has a tendency to release oxygen where   show
🗑
Bohr effect helps unload O2 when   show
🗑
in the alveoli, the partial pressure of oxygen is   show
🗑
partial pressure of O2 in alveoli is is about 35% less than   show
🗑
most of the CO2 transported by blood is   show
🗑
elastic cartilage that shields the opening to the larynx during swallowing is   show
🗑
pulmonary ventilation is the   show
🗑
show tissue lines the trachea  
🗑
cilia of pseudostratified columnar epithelium in trachea   show
🗑
respiratory structure with the smallest diameter   show
🗑
show lowered CO2 levels in blood & consequent constriction of cerebral blood vessels  
🗑
lowered CO2 levels in the blood cause cerebral blood vessels to __, reducing brain perfusion & causing ischemia   show
🗑
show nitrogen  
🗑
nitrogen makes up about 79% of atmospheric gas and has __ __ at normal atmospheric pressures   show
🗑
__ __ for extended periods of time result in nitrogen narcosis, or "rapture of the deep"   show
🗑
hyperpnea is   show
🗑
show as carbaminohemoglobin  
🗑
show basic respiratory rhythm  
🗑
show allow gas exchange  
🗑
example of an enzyme located in lung capillary membrane that acts on material in blood is   show
🗑
airway resistance is insignificant in relationship to gas flow because   show
🗑
transpulmonary pressure is difference between __ &__ pressure   show
🗑
increase in lung compliance __ __ lead to a decrease in the total respiratory compliance   show
🗑
show yawning  
🗑
breathing excessively high concentrations of oxygen for a long period of time would lead to   show
🗑
non-respiratory movements caused by irritation of diaphragm   show
🗑
dorsal respiratory group is   show
🗑
stimulating the contraction of the diaphragm   show
🗑
show blood and alveoli  
🗑
if intrapulmonary pressure & intrapleural pressure equalize   show
🗑
most prevalent gas in the __ is nitrogen   show
🗑
show start of expiration  
🗑
without the secretions of __ __ __ __, the lungs would collapse between breaths   show
🗑
during fetal life lungs are filled with fluid & all __ __ are made by the placenta   show
🗑
show highest; decreases  
🗑
show Hb affinity  
🗑
show bicarbonate ions in plasma  
🗑
increase in CO2 in blood will cause a(n) __ __ in H+ concentration (drop in pH)   show
🗑
external ventilation is   show
🗑
show hairs within the nasal cavity that filter coarse particles, such as pollen and dust, from inspired air  
🗑
inflammation of the nasal mucosa accompanied by excessive mucus production, nasal congestion, and postnasal drip   show
🗑
nasopharynx, oropharynx, laryngopharynx   show
🗑
show covered by a mucosa containing taste buds, and keeps food out of the lower respiratory passages  
🗑
show approximately 23 times within the lungs  
🗑
show elastic connective tissue found within the lungs  
🗑
show histotoxic hypoxia  
🗑
show respiratory system  
🗑
to supply body w/oxygen & dispose of carbon dioxide   show
🗑
processes involved in supplying the body with oxygen and disposing of carbon dioxide   show
🗑
show pulmonary ventilation  
🗑
movement of oxygen from lungs to blood & of carbon dioxide from blood to lungs   show
🗑
show transport of respiratory gases  
🗑
transport of respiratory gases accomplished by cardiovascular system using blood as   show
🗑
movement of oxygen from blood to tissue cells & of carbon dioxide from tissue cells to blood   show
🗑
pulmonary & external ventilation are the __ __ of the respiratory system   show
🗑
respiratory system cannot accomplish primary goal of obtaining oxygen & eliminating carbon dioxide unless these take place   show
🗑
if either respiratory or circulatory systems fail the body's cells begin to die from   show
🗑
show cellular respiration  
🗑
show cornerstone  
🗑
nose, nasal cavity, & paranasal sinuses, pharynx, larynx, trachea, bronchi & smaller branches & lungs which contain alveoli compose the __ system   show
🗑
show alveoli  
🗑
actual site of gas exchange in lungs; composed of respiratory bronchioles, alveolar ducts, & alveoli (all microscopic structures)   show
🗑
nose, nasal cavity, & paranasal sinuses, pharynx, larynx, trachea, bronchi, & lungs; provides fairly rigid conduits for air to reach gas exchange sites   show
🗑
show conducting zone organs  
🗑
although it brings about volume change that promotes ventilation, it is classified as part of the muscular system   show
🗑
only externally visible part of respiratory system; provides airway for respiration; moistens & warms entering air; filters & cleans inspired air; serves as resonating chamber for speech; houses olfactory receptors   show
🗑
area of nose between eyebrows   show
🗑
show external nose  
🗑
anterior margin of external nose   show
🗑
tip of nose   show
🗑
show philtrum  
🗑
show nostrils/nares  
🗑
show alae  
🗑
show superiorly  
🗑
show laterally  
🗑
skeletal framework of external nose is fashioned by flexible plates of hyaline cartilage __   show
🗑
show nasal bones  
🗑
root of nose is formed by   show
🗑
show flexible plates of hyaline cartilage of nose  
🗑
skin covering nose's dorsal & lateral aspects is thin & contains many   show
🗑
lies internally & posterior to external nose   show
🗑
show nasal septum  
🗑
show posterior nasal apertures  
🗑
show choanae  
🗑
show funnels  
🗑
show ethmoid; sphenoid  
🗑
floor of nasal cavity is formed by the __, which separates nasal cavity from oral cavity below   show
🗑
anteriorly the palate is supported by palatine bones & processes of maxillary bones, called   show
🗑
unsupported posterior portion of palate is the muscular   show
🗑
show nasal vestibule  
🗑
hairs of nasal cavity; filter coarse particles from inspired air   show
🗑
vibrissae means   show
🗑
lining slitlike superior region of nasal cavity; smell receptors   show
🗑
pseudostratified ciliated columnar epithelium containing scattered goblet cells that rest on lamina propria richly supplied with mucous & serous glands   show
🗑
mucous cells secrete   show
🗑
show enzymes  
🗑
antibacterial enzyme secreted in mucus of respiratory mucosa   show
🗑
respiratory glands secrete about a(n) __ of mucous containing lysozyme   show
🗑
show chemically  
🗑
show defensins  
🗑
high water content of __ __ acts to humidify inhaled air   show
🗑
__ __ of respiratory mucosa create gentle current that moves sheets of contaminated mucus posteriorly toward the throat where it is swallowed & digested by stomach juices   show
🗑
show sneeze reflex  
🗑
show sneeze  
🗑
show rich plexus  
🗑
show cold  
🗑
show nasal conchae  
🗑
show nasal meatus  
🗑
show surface area  
🗑
show heavier nongaseous  
🗑
show make it past nasal cavity  
🗑
not only function during inhalation to filter, heat, & moisten air, but also act during exhalation to reclaim this heat & moisture   show
🗑
show cools  
🗑
during exhalation __ __ precipitate moisture & extract heat from humid air flowing over them   show
🗑
the reclamation processes, by cooled nasal conchae __ amount of moisture & heat lost from body through breathing, helping us survive in dry & cold climates   show
🗑
mucous-membrane-lined, air-filled cavity   show
🗑
located in frontal, sphenoid, ethmoid, & maxillary bones, nasal cavity surrounded by ring of   show
🗑
lighten skull & together with nasal cavity they warm & moisten air   show
🗑
show mucus produced by sinuses  
🗑
show rhinitis  
🗑
show continuous  
🗑
show sinusitis  
🗑
show sinus headache  
🗑
show pharynx  
🗑
show divisions of pharynx  
🗑
show muscular pharynx  
🗑
show varies from one region to another  
🗑
show nasopharnyx  
🗑
show uvula  
🗑
show apertures  
🗑
show propelling mucus  
🗑
show pharyngeal tonsils  
🗑
infected & swollen __ can block air passage in nasopharynx, making it necessary to breath through the mouth; when chronically enlarged both speech & sleep may be distrubed   show
🗑
drain the middle ear cavities & allow middle ear pressure to equalize with atmospheric pressure; open into lateral walls of nasopharynx   show
🗑
ridge of pharyngeal mucosa that arches over each of auditory tube openings   show
🗑
show location  
🗑
superoposterior & medial to tubal tonsils; also play protective role   show
🗑
show oropharynx  
🗑
where nasopharynx blends into oropharyx, epithelium changes from pseudostratified columnar to a more protective   show
🗑
show food passage  
🗑
paired; lie embedded in oropharnygeal mucosa of lateral walls of fauces   show
🗑
cover posterior surface of tongue   show
🗑


   

Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
 
To hide a column, click on the column name.
 
To hide the entire table, click on the "Hide All" button.
 
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
 
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.

 
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how
Created by: lfrancois
Popular Anatomy sets