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Composition and Formation

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Question
Answer
What is Erythropoiesis?   RED Blood Cell production  
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Where do Erythrocytes develop?   Spleen in Fetuses, RED Bone Marrow in Adults  
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How do RBC develop?   Hemocytoblast (stem cells) --> Erythroblast --> Reticulocyte --> Erythrocyte  
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At what stage in RBC formation does the Hemoglobin form?   Erythroblast  
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At what stage in RBC formation is the Nucleus expelled?   Reticulocyte  
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How long does it take for and Erythrocyte to mature?   5 days  
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What is Hemoglobin?   RED, Iron containing pigment & Protein  
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What is the Heme (in Hemoglobin) and what is its function?   RED, Iron-containing Pigment - carries O2  
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What is the function of Globin (in Hemoglobin)?   Protein portion - carries CO2  
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What is Erythropoietin?   a Hormone from the Kidney which STIMULATES RBC Production  
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Where does RBC destruction take place?   in Liver or Spleen  
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What happens as RBC are destroyed?   1. Macrophages PHAGOCYTIZE worn/damaged cells; 2. Globin RETURNED to Circulation; 3. Heme recycled/stored; 4. Bilirubin excreted in Bile  
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