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RED Blood Cells
Composition and Formation
| Question | Answer |
|---|---|
| What is Erythropoiesis? | RED Blood Cell production |
| Where do Erythrocytes develop? | Spleen in Fetuses, RED Bone Marrow in Adults |
| How do RBC develop? | Hemocytoblast (stem cells) --> Erythroblast --> Reticulocyte --> Erythrocyte |
| At what stage in RBC formation does the Hemoglobin form? | Erythroblast |
| At what stage in RBC formation is the Nucleus expelled? | Reticulocyte |
| How long does it take for and Erythrocyte to mature? | 5 days |
| What is Hemoglobin? | RED, Iron containing pigment & Protein |
| What is the Heme (in Hemoglobin) and what is its function? | RED, Iron-containing Pigment - carries O2 |
| What is the function of Globin (in Hemoglobin)? | Protein portion - carries CO2 |
| What is Erythropoietin? | a Hormone from the Kidney which STIMULATES RBC Production |
| Where does RBC destruction take place? | in Liver or Spleen |
| What happens as RBC are destroyed? | 1. Macrophages PHAGOCYTIZE worn/damaged cells; 2. Globin RETURNED to Circulation; 3. Heme recycled/stored; 4. Bilirubin excreted in Bile |