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RED Blood Cells

Composition and Formation

What is Erythropoiesis? RED Blood Cell production
Where do Erythrocytes develop? Spleen in Fetuses, RED Bone Marrow in Adults
How do RBC develop? Hemocytoblast (stem cells) --> Erythroblast --> Reticulocyte --> Erythrocyte
At what stage in RBC formation does the Hemoglobin form? Erythroblast
At what stage in RBC formation is the Nucleus expelled? Reticulocyte
How long does it take for and Erythrocyte to mature? 5 days
What is Hemoglobin? RED, Iron containing pigment & Protein
What is the Heme (in Hemoglobin) and what is its function? RED, Iron-containing Pigment - carries O2
What is the function of Globin (in Hemoglobin)? Protein portion - carries CO2
What is Erythropoietin? a Hormone from the Kidney which STIMULATES RBC Production
Where does RBC destruction take place? in Liver or Spleen
What happens as RBC are destroyed? 1. Macrophages PHAGOCYTIZE worn/damaged cells; 2. Globin RETURNED to Circulation; 3. Heme recycled/stored; 4. Bilirubin excreted in Bile
Created by: kristel387