LECOM Micro CND infections
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Virus(3) that can invade CNS via peripheral nerves | HSV, VZV, Rabies
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CSF: +lymphocytes(T-cell predominant)+monocytes CLEAR | Virus Aseptic meningitis
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CSF: +PMNleukocytosis, ++proteins Turbid | pyogenic bacteria septic meningitis
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Gram- diplococcus polysaccharide capsule, pili, IgA protease, endotoxin, droplet spread | N. Men
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N. meningitidis Serotypes in America | B, C, Y
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N. Meningitidis serotypes in poor countries | A & W135
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N. meningitidis serotype there is no vaccine for | B
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Petichial, maculopapular rash on extremities, fever, sore throat, photophobia | N. meningitidis
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N. Meningitidis treatment and post treatment/family | Pen/ampicillin then rifampin
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Gram – coccobacillus hard to see in stain capsul, IgA protease, pili, endotoxin | H.I.b
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H.I.b treatment – prophylaxis | Ampicillin or ceftriaxone HIb polysaccharide vaccine
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Gram + cocci, capsule, IgA protease, no pili, | Strep. Pneumococci
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Strep. Pneumococci treatment | Vancomycin AND ceftriaxone or cefotaxime
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Gram + coccobaccillus, infecting immunocompromised & neonate | Listeria Monocytogenes
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L. monocytogenes treatment | Amp/gent
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Common bogs of neonatal meningitis | Group B hemolytic Streptococci & E.coli
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Capulate yeast, India Ink stained, in immune suppressed or AIDS, +culture | C.neoformans
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Treatment of Cryptococcus neoformans meningitis | Amphotericin B AND Flucytosine
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SW/Mexico/South America, no CSF or culture, serum compliment-fixing antibodies | Coccidiodes
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Well person, acute onset, after opening dirty pool, CSF slow motile amebae | Naegleria
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Immunocompromized, encephalitis, only in brain biopsy | Acanthamoeba
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Naegleria treatment | Amphotericin B, miconazole, Rifampin
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Ss RNA virus, HA, F, spasms, paralysis, death, Negri bodies | rhabdo virus Lyssavirus Rabies
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Eye damage, hydrocephalus, intracerebral calcifications | Toxoplasm Gondii
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Convulsions, coma, fever, African children | Plasmodium Falciparum
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Granuloma in the eye or brain, has cat or dog, + ELISA Ab | Toxocara
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Sheep hearderliver, lung brain, kidney cyst | Echinococcus granulosus
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Uncooked pork, cysts in muscle, brain or eye | Cysticercosis
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Muscle spasm ridged paralysis, sympathetic overdrive, sweating | C. tetani
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Descending weakness and paralysis, vertigo, respiratory failure | C. botulinum
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