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Cardiology

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Question
Answer
Systolic murmurs include:   AS, PS, MR, TR, MVP  
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Diastolic murmurs include:   AR, PR, MS, TS  
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Aortic stenosis   harsh midsystolic crescendo-decrescendo SEM best at RUSB 2nd R ICS, radiates to carotids.  
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AS: changes with squatting vs standing or Valsalva   Louder w/squatting, quieter w/standing or Valsalva;  
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Aortic regurgitation   soft, high pitched decrescendo diastolic blowing murmur, LSB at 2nd-3rd ICS  
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Mitral stenosis murmur   low-pitched, decrescendo, mid-diastolic rumble best at apex in LLD, loud opening snap after S2  
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Mitral regurgitation   Split S2, S3 gallop; high blowing holosystolic at apex radiating to axilla  
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Mitral valve prolapse (MVP) murmur:   Late systolic murmur at apex, mid-systolic click (louder squatting)  
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Harsh midsystolic crescendo-decrescendo SEM best at RUSB 2nd R ICS, radiates to carotids   Aortic stenosis  
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soft, high pitched decrescendo diastolic blowing murmur, LSB at 2nd-3rd ICS   Aortic regurgitation  
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low-pitched, decrescendo, mid-diastolic rumble best at apex in LLD, loud opening snap after S2   Mitral stenosis  
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Mid-systolic click   Mitral valve prolapse (MVP)  
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SEM at pulmonic, fixed split S2   ASD  
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Elderly w/ systolic murmur   Aortic stenosis: due to calcifications (age related) or bicuspid valve (congenital)  
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Diamond shaped, blowing holosystolic murmur, best at RUSB, 2nd interspace; Pulsus parvus et tardus   Aortic stenosis  
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Low pitched, diastolic rumble near apex with opening snap, best in LLD position   Mitral stenosis (ARMS are BAD); echo, balloon or MVR for sxs  
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Systolic ejection murmur heard best at base with radiation to left clavicle   Pulmonary stenosis  
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Female or Post MI, systolic murmur best at apex preceded by click without radiation   Mitral valve prolapse  
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High holosystolic murmur heard best at apex with radiation to left axilla, palpable LV heave at apex   Mitral regurgitation  
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New murmur (often apical systolic) after MI =   Mitral regurgitation (caused by papillary muscle rupture)  
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Murmur & Hx rheumatic heart disease   Mitral stenosis  
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Continuous harsh, machine-like murmur at 2nd ICS =   PDA (wide pulse pressure and loud S2)  
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Cyanotic infant with systolic thrill at LSB, systolic ejection murmur +/- click, and S2:   Tetralogy of Fallot  
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High pitched holosystolic murmur at LSB (L-to-R), may have diastolic murmur of pulmonic regurgitation:   VSD  
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Infant w/ dyspnea, difficulty feeding. Holosystolic murmur at LSB, 3rd ICS. LVH & RVH   VSD  
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Auscultate when pt is squatting: what effect?   Increases aortic stenosis; decreases HCM (increases preload; more blood separates anterior leaflet from septum => quieter murmur)  
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Austin Flint murmur =   mid-diastolic apical murmur when pt leans forward holding breath on expiration (aortic regurgitation)  
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Aortic area =   RIGHT 2nd ICS (aortic stenosis, aortic regurgitation, HCM  
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Pulmonic area =   LEFT 2nd ICS (PDA)  
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Erb's point =   Left 3rd ICS (aortic or pulmonic valve dz  
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Aortic regurgitation is best heard here:   Erb's point  
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Tricuspid area =   LEFT 4th ICS  
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Mitral area =   LEFT 5th ICS (cardiac apex)  
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pulsus paradoxus =   >10mm Hg SBP decline on inspiration; 2/2 pericardial effusion/tamponade, pericarditis, asthma attack, tension PTX, SVC obstruction  
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Valsalva or pt standing, has what effect?   Decreases aortic stenosis murmur. Increases HCM murmur (decreased venous return & preload -> less blood to separate leaflet from enlarged septum: louder murmur).  
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Put pt in LLD to auscultate:   MS at apex, or S3, S4  
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Auscultate w/pt sitting, holding breath in expiration and leaning forward:   Aortic regurgitation at LSB  
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HCM auscultation:   Loud S4 at LSB; murmur similar to aortic stenosis, at LSB & apex  
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Graham Steell murmur =   high pitched decrescendo diastolic murmur at LSB = miral stenosis +/- severe pHTN. Heard in mitral stenosis & pulmonic regurg (2/2 pHTN)  
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Pulmonic stenosis murmur =   Harsh midsystolic crescendo-decrescendo SEM at LUSB & radiates to back/neck; inc with inspiration; wide split S2. Longer murmur = more severe dz  
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Pulmonic regurg (2/2 CHD) murmur =   Lower-pitched Graham Steell-type murmur; late diastolic at 3rd-4th left ICS; RV heave  
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Tricuspid stenosis murmur =   Low mid-diastolic / presystolic rumbling at 4th & 5th ICS, LSB, or below xiphoid; Carvallo sign  
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Carvallo sign =   murmur intensified by inspiration (eg, TS)  
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Murmur of ASD:   fixed wide split S2; early: systolic flow murmur at left 2nd-3rd ICS & SEM at pulmonic valve; later: low diastolic murmur at LUSB  
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Murmur in a patent ductus arteriosus:   L to R shunt: continuous precordial murmur (machinery), thrill; R to L shunt: diastolic Graham Steell murmur  
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Tricuspid regurgitation murmur =   high pitched pansystolic murmur (4th ICS in parasternal region); increases on inspiration & decreases on expiration & standing/Valsalva  
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Murmurs radiate in the direction of:   blood flow  
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Inspiration causes:   increased venous return to right ventricle; decreased venous return to left ventricle & reduced LV volume  
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Expiration allows which cardiac vessels to re-expand?   pulmonary vessels & aorta  
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Which murmurs are accentuated by inspiration & expiration?   Inspiration: accentuate Right heart murmurs. Expiration: accentuate Left heart murmurs.  
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Squatting (increasing preload) intensifies all murmurs EXCEPT:   HCM & MVP (but squatting makes MVP click accentuated & earlier)  
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Handgrip increases systemic arterial pressure / HR and increases which murmurs (3)?   MS, MR, AR, MVP. Decreases AS and HCM  
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Drug that mimics the effect of standing / Valsalva:   amyl nitrate  
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Murmur in coarctation of aorta   Ejection murmur at aortic area & LSB, radiates into left axilla & left back  
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VSD murmur:   High pitched holosystolic murmur at LSB (L-to-R); small defects have diamond shaped murmur; may have diastolic murmur of pulmonic regurgitation  
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80% of patients with this condition have A-fib and diastolic opening snap of S1   Mitral stenosis  
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Murmur that may cause cardiac dilatation, weakened cardiac muscles, pulmonary HTN due to increased blood flow:   VSD (>ASD)  
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Aortic murmurs: pulse pressures   AS: narrow pulse pressure. AR: wide pulse pressure  
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Auscultate this murmur with bell   Mitral stenosis  
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MS vs TS: louder with expiration or squatting?   MS louder with expiration or squatting; TS quieter with expiration  
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MR louder with:   squatting or in LLD  
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MVP increases with:   standing /Valsalva or handgrip (increased afterload)  
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