Kaplan MCAT Biology Chapter 1
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Cell Theory | All living things are composed of cells - The cell is the basic functional unit of life - Cells arise only from pre-existing cells - Cells carry genetic information in the form of DNA
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What are the 3 primary tools used to study cells? | Microscopy, Autoradiography, Centrifugation
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What are the 3 primary types of microscopes | Compound light microscope, Phase contrast microscope, Electron microscope
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What controls the amount of light passing through specimens using compound light microscopy | diaphragm
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Which types of microscopes are used to observe nonliving specimens | Compound light microscopes and electron microscope
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What type of microscope is used to observe living specimens | Phase contrast microscope
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Autoradiography uses what to trace and identify cell structures and biochemical activity | radioactive molecules
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What cellular process is autoradiography used to study | protein synthesis - by labeling amino acids with radioactive isotopes
DNA & RNA synthesis specifically
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cell mixtures are separated in centrifugation by what quality | cell type/density
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cell fragments are separated in centrifugation based on _______ | density
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Prokaryotic DNA | circular - concentrated in nucleoid region
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Smaller rings of DNA | plasmids - contain just a few genes
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A purpose of plasmids | allow cell to survive adverse conditions - explanation for antibiotic resistance
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Where does respiration occur in the prokaryotic cell | cell membrane
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Centrioles are found in ______ cells | eukaryotic animal
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Cytosol contents | free proteins, nutrients,solutes, cytoskeleton
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Purpose of cytoskeleton | give cell shape and anchor organelles
aid in cell maintenance and intracellular transport
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Organelles | endoplasmic reticulum, golgi apparatus, vesicles, vacuoles, lysosomes, microbodies, mitochondria, chloroplasts, centrioles
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Cholesterol molecules in phospholipid bilayer purpose | cell fluidity
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transport proteins | membrane-spanning proteins that allow certain ions to pass through
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cell adhesion molecules (CAMs) | proteins that contribute to cell recognition and adhesion - important during development
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Receptors | glycoproteins that bind to specific molecules in the cell's external environment - may carry molecule into cell by pinocytosis
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DNA is complexed with structural proteins called __________ to form _________ | histones; chromosomes
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Where is rRNA synthesized | nucleolus
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What is the site of protein production | ribosomes
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Where are ribosomes synthesized | mucleolus
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What is the smooth ER involved in | lipid synthesis and etoxification of drugs and poisons
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What pH are the enzymes of lysosomes maximized at? | pH 5
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What are the 2 types of microbodies | peroxisomes and glyoxysomes
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What is the role of peroxisomes | contain oxidative enzymes that catalye a class of reactions in which peroxide is produced - break down fats into smaller molecules
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Where are glyoxysomes found and what is their role | found in fat tissue of germinating seedlings - used to convert fats into sugars until seedling is mature enought to produce its own sugar
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What is the site of aerobic respiration | mitochondria
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What are the characteristics of the outer membrane of mitochondria | smooth and acts as a sieve - allowing molecules to pass on basis of size
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What is the area between outer and inner membrane of mitochondria called | intemembrane space
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What are the characteristics of the intermembrane space | many convolutions called cristae, high protein content - contains many of the proteins of the electron transport chain
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What is the area bound by inner membrane of mitochondria called | mitochondrial matrix
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What is the site of many of the reactions of respiration | mitochondrial matrix
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How do mitochondria differ from other organelles | they are semiautonomus - they contain their own DNA (circular) and ribosomes, they self replicate by binary fission
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What type of cells have cell walls? | Plants and fungi
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What are centrioles composed of? | microtubules
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Role of centriole | spindle organization during cell division - direct separation of chromosomes
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Where are the centrioles? | Animals have a pair of centrioles that are oriented at right angles to one another in a region called the centrosome
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What type of cells have centrioles? | animal cells
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Microtubules | hollow rods made of polymerized tubulins that radiate throughout the cell and provide support
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What provides the framework for organelle movement? | microtubules
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What are cilia and flagella specialized arrangements of? | microtubules
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Microfilaments | solid rods of actin involved in cell movement and support
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Muscle contraction based on interaction between what | actin and myosin
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What moves materials across plasma membrane | microfilaments
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intermediate filaments | collection of fibers involved in maintenace of cytoskeletal integrity
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In what ways can substances move in and out of a cells | simple diffusion (osmosis), facilitated diffusion, active transport, endocytosis, exocytosis
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Simple diffusion | net movement of dissolved particles down their concentration gradient (high to low)
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Which modes of transport of materials in and out of cells are passive processes? | simple diffusion (osmosis), and facilitated diffusion
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Osmosis | simple diffusion of water
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hypertonic solution | describes the medium when cytoplasm has lower solute concentration than extracellular medium
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If the medium is hypertonic, water will... | flow out of cell, causing cell to shrink
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hypotonic solution | describes the medium when cytoplasm has higher solute concentration than the extracellular medium
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If the medium is hypotonic, water will.... | flow into the cell, causing it to sell
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When concentrations of medium and cytoplasm are equal, the cell and medium are said to be | isotonic - no net flow of water
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Facilitated diffusion | net movement of dissolved particles down their concentration gradient with the help of transport proteins
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Active transport | net movement of dissolved particles against their concentration gradient with the help of transport proteins
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What maintains the membrane potentials in specialized cells such as neurons | active transport
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What are the 4 basic types of tissue | epithelial tissue, connective tissue, nervous tissue, muscle tissue
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epithelial tissue | covers surfaces of body and lines the cavities; protects against injury, invasion and desiccation; involved in absorption, secretion and sensation
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Connective tissue involved in... | involved in body support
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What is included in connective tissue | bone, cartilage, tendons, ligaments, adipose tissue, and blood
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Nervous tissue | conposed of specialized cells (neurons) that are involved in the perception, processing, and storage of information
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What are the 3 types of muscle tissue | skeletal, cardiac, smooth
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Viruses | acellular structure composed of nucleic acid enclosed by a protein coat
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Nucleic acid of viruses can be either _____ or _______ | linear or circular
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protein coat of a virus | capsid
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Bacteriophages | Viruses that infect bacteria
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