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CHAPTER 14 LYMPHATIC SYSTEM

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Answer
transports excess tissue fluid to bloodstream   lymphatic system  
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lymphatic system   absorbs fats  
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helps defend body against disease causing agents   lymphatic system  
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lymphatic pathways   capillaries vessels trunks/collecting ducts  
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lymphatic capillaries   microscopic receive lymph through own thin walls  
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closed-ended tubes extend into interstitial spaces   lymphatic capillaries  
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lymphatic vessels   similar to veins, only thinner & valves prevent backflow of lymph  
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lead to lymph nodes & merge into lymphatic trunk   larger lymphatic vessels  
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lymphatic collecting duct   join subclavian veins  
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lymphatic trunks   lead to 2 collecting ducts  
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thoracic & right lymphatic ducts   2 collecting ducts of lymphatic trunks  
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lymph physiology   returns protein molecules to bloodstream & transports foreign particles to lymph nodes  
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lymph formation   increased pressure in interstitial space force tissue fluid into lymphatic capillaries fluid=lymph  
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tissue fluid origin   blood plasma  
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lacks large proteins small proteins filtered out blood capillaries to interstitial spaces   tissue fluid  
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as protein concentration of tissue fluid increases, colloid osmotic pressure increases   tissue fluid formation  
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lymph under low pressure   no flow ready w/o external aid  
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lymph movement   contraction of skeletal muscles  
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contraction of smooth muscle in walls of large lymphatic trunks   lymph movement  
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lymph movement   low pressure in thorax by breathing movements  
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lymph node structure   subdivided into nodules  
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nodules   contain masses of lymphocytes & macrophages  
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lymph node location   aggregate in groups/chains along paths of larger lymphatic vessels  
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lymph node physiology   filter harmful foreign particles from lymph  
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center for production of lymphocytes & contain phagocytic cells   lymph node physiology  
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thymus   lymphatic tissue subdivided into lobules  
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slowly shrinks after puberty   thymus  
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some lymphocytes leave ____ & provide immunity   thymus  
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spleen   resembles large lymph node subdivided into lobules  
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spaces within splenic lobules are filled with ____   blood  
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contains many macrophages, filter foreign particles & damaged red blood cells from blood   spleen  
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body defenses against infection   body has innate & adaptive defenses against infection  
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innate nonspecific defenses   species resistance mechanical & chemical barriers natural killer cells inflammation phagocytosis fever  
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fever   high body temp= decrease in blood iron level & increase in phagocytic activity hamper infection  
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neutorphils & monocytes   most active phagocytes in blood  
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monocytes   give rise to macrophages, remain fixed in tissues  
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phagocytic cells association   linings of blood vessels in bone marrow liver, spleen, lungs, lymph nodes  
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phagocytes   remove foreign particles from tissue & body fluids  
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inflammation   tissue response to injury/infection  
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localized redness,swelling,heat,pain   inflammation  
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chemicals released by damaged tissue attract ____ to site   WBC  
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connective tissue forms sac around injured tissue & block spread of ____   pathogens  
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natural killer cells   secrete perforins  
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perforins   destroy cancer cells & cells infected w/ viruses  
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species resistance   each species is resistant to certain diseases that affect other species  
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mechanical barriers   block entrance of pathogens  
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skin & mucous membranes   mechanical barriers  
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activation of complement proteins in plasma stimulate   inflammation attract phagocytes enhance phagocytosis  
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enzymes in gastric juice & tears kill ____   pathogens  
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interferons   chemical barrier  
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stimulate unifected cells to synthesize antiviral proteins stimulating phagocytosis   interferons  
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interferons   block proliferation of viruses  
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enhance activity of cells that help resist infections   interferons  
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stifle tumor growth   interferons  
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adaptive specific defenses/immunity   antigens lymphocyte T cells-cellular immune response B cells-humoral immune response antibody immune responses immunity allergic reactions transplantation tissue rejection autoimmunity  
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before birth, body cells inventory ___ & other large molecules   self proteins  
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lymphocytes self antigens   after inventory, _____ develop receptors allow differentiation of nonself & ____  
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nonself antigens   combine w/ T&B cell surface receptors & stimulate these cells to cause immune reaction  
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haptens   small molecules can combine w/ larger ones, =antigenic  
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