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Muscle tissue

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show posture  
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show stabilize  
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show heat  
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show contracts rapidly  
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in skeletal muscles, each muscle is a(n)   show
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striated; involuntary; responsible for pumping blood through body; specialized muscle   show
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show heart’s pacemaker  
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neural controls, in cardiac muscles   show
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spindle-shaped cells w/1 centrally located nucleus; no externally visible striations; involuntary; forces food, feces & other substances through internal body channels   show
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show walls of hollow visceral organs, such as stomach, urinary bladder, & respiratory passages  
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ability to recoil & resume resting length after being stretched   show
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ability to be stretched/extended   show
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show contractility  
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show excitability  
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most skeletal muscles __ __ & are attached to bone in at least __ places   show
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show muscle’s origin  
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epimysium of muscle is fused to periosteum of a bone/perichondrium of cartilage   show
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muscle's CT wrapping extends beyond muscle via tendons/aponeurosis   show
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sheath of CT surrounding each muscle fiber; consists of fine areolar CT   show
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show perimysium  
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show epimysium  
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sarcolemma   show
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show muscle fiber  
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show cytoplasm of muscle cell  
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show sarcoplasm  
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myofibrils, sarcoplasmic reticulum, & T tubules are found in the muscle fiber's   show
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show muscle fiber (cell)  
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show striations, sarcomere & myofilaments  
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striations of myofibril are due to   show
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sarcomere is region of myofibril between 2   show
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show myofilaments  
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show actin  
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thick myofilaments composed of protein   show
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show rod-like tail & 2 globular heads  
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two interwoven, polypeptide chains are found in myosin molecule's   show
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form cross bridges, found in myosin molecules   show
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subunits of thin myofilaments contain active sites to which   show
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show tropomyosin & troponin  
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show endoplasmic reticulum  
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show perpendicular cross channels  
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sarcoplasmic reticulum stores __ __ & releases them when muscle is stimulated to contract   show
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extensions of sarcolemma, penetrate deep into cell’s interior   show
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T tubules associate w/paired terminal cisternae to form __   show
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show nerve stimulation  
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show slide past; overlap  
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show relaxed state  
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show shorten; shortens  
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show skeletal muscle contraction  
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show rise in intracellular Ca2+ levels  
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sequence of events by which transmission of an action potential along the sarcolemma leads to the sliding of myofilaments; linking electrical signal to contraction is called   show
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skeletal muscles are stimulated by   show
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__ of motor neurons branch as they enter muscles   show
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each __ __ forms a neuromuscular junction w/muscle fiber   show
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axon branch; folds of sarcolemma at motor end plate w/acetyl choline receptors; synaptic vesicles in axon terminal; synaptic cleft; are all components of a(n)   show
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show nerve impulse  
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at NMJ, voltage-gated __ __ in axon terminal open, allowing __ enter axon   show
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show axonal membrane  
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at NMJ, fusion of synaptic vessels w/axonal membrane releases ACh into synaptic cleft via __   show
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show gated channels  
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show action potential in muscle  
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at NMJ, ACh is quickly destroyed by __ acetylcholinesterase   show
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show resting state  
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show negative compared to outside  
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difference in charge of sarcolemma, negative compared to outside, is known as   show
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show ACh binds to its receptors on sarcolemma Na/K channels open  
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once ACh binds to its receptors on sarcolemma Na/K channels open, sodium channels open first- Na+ diffuses in & causes a patch of sarcolemma to become   show
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show depolarization  
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initially, depolarization, is a local electrical event called   show
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show action potential/propagation  
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if action potential initiated, voltage-gated Na+ channels open in adjacent areas of sarcolemma causing it to   show
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action potential travels   show
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show contraction of a muscle  
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show changes  
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in action potential/repolarization, Na+ channels __ & K+ channels __   show
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show diffuses; resting  
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occurs in same direction as depolarization   show
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in excitation/contraction coupling, action potential propagates   show
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show Ca2+ release from terminal cisternae  
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show troponin; exposed  
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in excitation/contraction coupling, myosin heads attach forming a __ __; power stroke of myosin head causes sliding of __ __ toward center of sarcomere   show
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show excitation/contraction coupling  
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during excitation/contraction coupling, as action potential ends, removal of Ca+2 by __ __   show
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stiffening of muscles after death; cross bridge detachment requires ATP   show
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show ATP  
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refers to activation of cross bridges   show
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force exerted by contracting muscle on an object   show
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show load  
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occurs when tension generated by cross bridges exceeds forces opposing it   show
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when cross bridges become inactive, tension declines & relaxation occurs   show
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show isometric contraction  
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show standing, sitting, posture  
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muscle changes in length; muscle tension overcomes load & moves load   show
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isotonic contraction are used in   show
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show motor unit  
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muscles that control fine precise movements e.g. fingers, eyes (few muscle fibers) have   show
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large weight-bearing muscles (many muscle fibers) e.g. thighs, hips have   show
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show muscle twitch  
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show latent period  
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phase of a muscle twitch when cross bridges form   show
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show period of relaxation  
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factor affecting muscle tension in which muscle stimulated rapidly, contractions are summed up become stronger   show
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factor affecting muscle tension in which the more the motor fibers are contracting (by recruitment of more motor units) the stronger the contraction   show
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show degree of muscle stretch  
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degree of muscle stretch is optimum muscle length at which they can   show
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degree of muscle stretch, number of muscle fibers contracting, & frequency of stimulation   show
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single stimulus results in a single contractile response   show
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with increased frequency of stimulus muscle does not relax completely; contraction force increasing   show
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show incomplete tetanus  
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show complete tetanus  
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produces weak contraction because overlapping thin filaments interfere with each other   show
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show overstretched sarcomere  
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maximum tension develops at this optimum overlap of thick & thin filaments; all cross bridges can cycle   show
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show muscle tone  
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muscle tone keeps muscles __ & ready to __ to stimulus   show
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show spinal reflexes  
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show power stroke of myosin head  
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show detaching  
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ATP in muscle contraction is used for pumping __ back into sarcoplasmic reticulum   show
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show ATP regeneration  
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during contraction: hydrolysisphosphate group combines w/ADP to form ATP (immediate source)   show
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during contraction: when muscle contractile activity reaches 70% of maximum, bulging muscles compress blood vessels; impaired O2 delivery   show
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during contraction, largest amount of ATP formed   show
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muscle is being stimulated but is in a state of physiological inability to contract   show
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show low  
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show lactic acid  
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show speed of contraction  
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show oxidative or glycolytic fibers  
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show oxidative fibers  
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show glycolytic fibers  
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characteristics intermediate btwn oxidative & glycolytic fibers   show
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red fibers; depend on aerobic ATP production; have more myoglobin, capillaries, mitochondria, low glycogen; contract slowly, are fatigue resistant & have high endurance   show
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example of slow oxidative fibers   show
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show fast glycolytic fibers  
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show hitting baseball, pushing piano  
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show mixture  
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show atrophy  
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show immobilization  
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show paralysis  
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show hypertrophy  
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example of hypertrophy   show
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composed of spindle-shaped fibers w/central nuclei   show
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smooth muscle is found in   show
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smooth muscle is organized in two layers of   show
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show longitudinal & circular  
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show structures neuromuscular  
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smooth muscles autonomic nerve fibers have __ that release neurotransmitters   show
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smooth muscle sarcoplasmic reticulum is   show
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show absent  
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show there are no sarcomeres  
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show troponin complex  
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show smooth muscle contraction  
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mostly whole sheets of smooth muscle contract together, because of __ __, as __ __ spread from cell to cell   show
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show contract  
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in smooth muscle, actin & myosin interact by the   show
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in smooth muscle, final trigger for contractions is a(n)   show
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in smooth muscle, sliding filament mechanism   show
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in smooth muscle, Ca2+ enter mainly from the __ __   show
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in smooth muscle, some Ca2+ is __ __ SR   show
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when stretched to an optimal length contract more strongly   show
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smooth muscle responds to stretch briefly by __ __ then adapts to its new length & relaxes   show
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enables organs such as the stomach and bladder to be able to store contents without strong contractions expelling contents   show
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found in walls of hollow visceral organs; cells contract as a unit (have gap junctions); arranged in sheets; show stress-relaxation response   show
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show smooth muscle multiunit  
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show hyperplasia  
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smooth muscles can undergo hyperplasia   show
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examples of smooth muscle hyperplasia stimulation is   show
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during pregnancy, estrogen stimulates uterine growth to accommodate the increasing size of the growing fetus, causing   show
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because skeletal & smooth muscles are __ they are called muscle fibers   show
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show muscle  
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show myo-/mys-  
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show sarco-  
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word root means husk   show
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show skeletal muscle tissue  
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show skeletal muscles  
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show heart walls  
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allow heart to speed up for brief periods of exertion   show
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show conductivity  
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show muscle functions  
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skeletal muscles are responsible for all __ & __   show
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skeletal muscles enable you to __ __ to changes in external environment   show
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show maintain blood pressure  
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show body mass  
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show generating heat  
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show smooth muscles  
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show composition of skeletal muscles  
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in general, __ __ is served by one nerve, artery, & 1/more veins   show
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show contract in without nerve stimulation  
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long & winding w/numerous cross-links, which is feature that accommodates changes in muscle length   show
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muscle capillaries __ when muscle is stretched   show
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show contort  
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show CT sheaths  
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show fascicles  
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CT sheaths contribute to __ of muscle tissue   show
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CT sheaths provide entry & exit routes for   show
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show muscle's insertion  
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when muscle contracts movable bone, __ moves towards immovable/less movable bone   show
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cord of dense fibrous tissue attaching muscle to bone   show
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show aponeurosis  
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show aponeurosis/tendon  
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show their durability & size  
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more __ than fleshy muscle can pass over __   show
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show glycosomes  
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oxygen-binding, red pigment in muscle   show
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show hemoglobin  
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show myofibril  
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myofibrils account for about 80% of   show
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repeating series of dark & light bands, evident along length of each myofibril   show
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show A bands  
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light striations within muscle cells   show
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lighter region in midsection of A band   show
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dark line that bisects each H zone vertically; formed by molecules of protein myomesin   show
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show Z disc  
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smallest contractile unit of muscle; extends from 1 Z disc to next   show
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show functional unit  
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show A; I  
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located in center; contain myosin; extend entire length of A band   show
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show thin filaments  
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contain desmin; extend from Z disc; connect each myofibril to next throughout width of muscle cell   show
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consists of 2 heavy & 4 light polypeptide chains; has rod-like tail attached by flexible hinge to 2 globular heads   show
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rod-shaped protein, spiral about actin core & hep stiffen & stabilize it   show
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show block  
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show troponin  
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troponin & tropomyosin help control __ __ involved in contraction   show
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show elastic filament  
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show titin  
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titin forms __ of thick filament   show
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show organization of A band  
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titin holds thick filaments in place, helping muscle cell to   show
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show ordinary range of extension  
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show resist excessive stretching  
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show dystrophin  
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show bind filaments or sarcomeres together & maintain their alignment  
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SR & T tubules are two sets of intracellular tubules that   show
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tubules of SR run longitudinally along   show
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major role of SR is to regulate   show
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T tubules increase muscle fiber's __ __   show
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successive groupings of 2 membranous structures (terminal cisterna, T tubule, & terminal cisterna   show
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show conduct impulses to deepest regions of muscle cell to every sarcomere  
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show voltage sensors  
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form gated channels through which Ca2+ can be released from SR cisternae   show
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term contraction refers to   show
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show sliding filament model of contraction  
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show stimulated by nerve ending so change in membrane potential occurs  
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show action potential  
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show generate & propagate action potential along its sarcolemma  
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show short-lived rise in intracellular calcium ion levels  
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nerve cells that activate skeletal muscle fibers are called   show
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long thread-like extensions of somatic motor neurons   show
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show neuromuscular junction  
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when axon of motor neuron divides when entering muscle, the short curling branches it gives off are collectively called   show
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each muscle fiber has   show
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fluid-filled (with ACh) space at a synapse   show
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chemical transmitter substance released by some nerve endings; neurotransmitter   show
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trough-like part of muscle fiber's sarcolemma   show
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show large surface area  
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show axonal endings, synaptic cleft, junctional folds  
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show acetylcholinesterase  
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disease characterized by drooping upper eyelids, difficulty swallowing & talking, & generalized muscle weakness, involves shortage of ACh receptor   show
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show polarized  
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loss of a state of polarity; loss/reduction of negative membrane potential   show
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show end plate potential  
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show repolarization  
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show refractory period  
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show electrical conditions  
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show ionic conditions  
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show unstoppable  
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show latent period  
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show muscle is relaxed  
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show removed  
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show sliding of thin filament  
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show increase greatly  
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show excitation  
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show myogram  
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show period of time btwn stimulation & onset of muscle contraction; excitation-contraction coupling occurs here  
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period of contraction   show
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period of relaxation   show
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muscle twitches may result from   show
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relatively smooth; vary in strength as different demands placed on them   show
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show graded muscle responses  
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show greater muscular force  
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show temporal/wave summation  
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each stimulus causes contraction to be initiated when muscle has only partly relaxed from previous contraction   show
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sustained muscular contraction caused by series of nerve stimuli repeated so rapidly that individual muscular responses are fused   show
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fused/complete tetanus happens __ in real world   show
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show prolonged; fatigue  
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wave summation contributes to __ force   show
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show primary function of wave summation  
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show recruitment/multiple motor unit summation  
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show subthreshold stimulus  
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show threshold stimulus  
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stimulus strong enough to evoke greatest possible response; represents point at which all muscle's motor units are recruited   show
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increasing stimulus intensity beyond maximal stimulus   show
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show dictated  
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show size principle  
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size principle dictates that largest motor units containing large, coarse muscle fibers controlled by largest least excitable neurons & are activated only when   show
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show occur in small steps  
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show progressively greater  
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although all motor unit of a muscle may be recruited simultaneously to produce strong contraction, they are more commonly activated __ in body   show
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show relaxed; contracted  
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show concentric contraction  
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show eccentric contraction  
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show more forceful  
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show contract concentrically  
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CP-ADP reaction is catalyzed by   show
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show glycolysis  
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2 ATP produce   show
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product of anaerobic metabolism, especially in muscle   show
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show impaired blood flow & O2 delivery  
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energy-yielding conversion of glucose to lactic acid in muscle, when sufficient oxygen is not available   show
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during __ __, lactic acid is end product of cellular metabolism of glucose   show
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95% of ATP used for muscle activity from from   show
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when ATP demands are within capacity os aerobic pathway, light to moderate muscular activity can   show
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show glycolysis contributes more & more of total ATP generated  
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show aerobic endurance  
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show anaerobic threshold  
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activities requiring surge of power lasting only few seconds (i.e. weight lighting, diving, etc.) rely   show
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more on-and-off or burst-like activities (i.e. tennis, soccer, etc.) appear to be fueled   show
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prolonged activities (i.e. marathons, jogging) where endurance over power is goal, depend   show
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show prolonged exercise  
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show contractures  
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show writer's cramp  
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several __ __contribute to muscle fatigue   show
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lactic acid is more important in provoking __ fatigue than __ fatigue   show
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excessive intracellular accumulation of lactic acid raises concentration of H+ and alters __ __   show
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show counteract  
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show alter E-P coupling  
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show regulation; release  
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show anaerobic muscle contraction  
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show oxygen deficit (definition)  
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oxygen deficit represents difference btwn amount of oxygen __ for totally aerobic muscle activity & amount __ __   show
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only about 40% of energy released during muscle activity is   show
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greater muscle's __ __, more tension can develop & greater its strength   show
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show internal tension  
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show external tension  
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show optimal operating length  
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show ideal length-tension relationship  
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show split ATP  
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in slow/fast fibers, difference in speed reflects on pattern of __ __ of motor neurons   show
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show slow oxidative (SO), fast oxidative (FO), or fast glycolytic (FG) fibers  
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show aerobic exercise  
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moderately weak but sustained muscle activity   show
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high-intensity exercise in which the muscles are pitted against high resistance or immovable forces and, as a result, muscle cells increase in size   show
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smooth muscle fibers run parallel to long axis of organ; when muscle contracts organ dilates & shortens   show
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show circular layer  
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show diffuse junctions  
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epimysium   show
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show surround each muscle fiber  
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show surround each muscle bundle  
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deep fascia   show
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sarcolemma   show
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show cytoplasm of a skeletal muscle fiber  
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sarcoplasmic reticulum   show
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myofibril   show
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show functional unit of a skeletal muscle fiber  
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show area of the sarcomere with overlapping thick and thin filaments  
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I band   show
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H band   show
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show cross bridges  
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synaptic knob   show
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show space btwn neuron & muscle  
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show contains receptors for ACh  
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twitch   show
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show muscle producing peak tensions with visible relaxation during rapid cycles of contraction and relaxation  
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complete tetanus   show
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wave summation   show
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endurance-type activities   show
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show best suited for fast oxidative fibers  
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show best suited for fast glycolytic fibers  
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skeletal muscle fibers   show
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show branching chains of cells; uni- or binucleate striations; intercalated discs  
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smooth muscle cells   show
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show ability to receive and respond to a stimulus  
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show ability to shorten forcibly when adequately stimulated  
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show ability to be stretched or extended  
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show ability of a muscle to resume its resting length after being stretched  
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isotonic contraction   show
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show contraction of muscle during which the tension continues to increase but the muscle neither shortens nor lengthens  
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concentric contraction   show
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eccentric contraction   show
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skeletal muscle voluntary via __ __ of the somatic nervous system   show
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involuntary; intrinsic system regulation, hormones and autonomic nervous system controls   show
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involuntary, autonomic nerves, hormones, local chemicals   show
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acetylcholine (ACh)   show
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creatine phosphate   show
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show O2 storage molecules in muscles  
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lactic acid   show
🗑
show muscle fibers that contract quickly and rely on aerobic respiration for ATP  
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show muscle fibers that are most resistant to fatigue  
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fast glycolytic fibers   show
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show cramp  
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show fibromyositis  
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muscle pain resulting from any muscle disorder   show
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excessive stretching and possible tearing of a muscle caused by muscle overuse or abuse   show
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show time btwn stimulus/electrical event & mechanical event of contraction  
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show time during which the muscle is shortening  
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show time during which the muscle is returning to its original length  
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refractory period   show
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show propagation of an electrical current along sarcolemma  
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resting potential   show
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repolarization   show
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show time when fiber cannot be stimulated until repolarization is complete  
🗑
show electrical event occurring only at neuromuscular junction  
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show released by terminal cisternae into the sarcoplasm to bind with troponin  
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acetylcholinesterase   show
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calmodulin   show
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show outside positive relative to the inside  
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depolarization & generation of action potential   show
🗑
show increased positive charge inside sarcolemma changes permeability of adjacent areas, opening voltage-regulated Na+ channels  
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repolarization   show
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show pulling on something to change its position  
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maintaining posture   show
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stabilizing joints   show
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generation of heat   show
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show changes shape during the contraction cycle  
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actin   show
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show covers the binding site  
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troponin   show
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show entire  
🗑
as an axon enters a muscle, it branches into a number of axonal terminals, each of which forms a neuromuscular junction with a single muscle fiber. A motor neuron and all the muscle fibers it supplies is called a(n)   show
🗑
show Ca2+  
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each skeletal muscle fiber is controlled by a neuron at a single   show
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show composition of the structure known as a triad in a skeletal muscle fiber  
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show sliding filament model  
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epimysium is the   show
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muscle tone   show
🗑
show type of muscle contraction in which the muscle fibers produce increased tension, but the muscle neither shortens nor lengthens  
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show substance that increases in quantity during repetitive muscle contraction  
🗑
action potential   show
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calmodulin   show
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show a myofibril  
🗑
show globular heads of thick filaments  
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show refractory period of muscle cell  
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cause of rigor mortis   show
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95% of the energy needed for contraction during moderate exercise   show
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show serve as a communication network that coordinates the contraction of each myofibril that makes up the muscle fiber  
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actin   show
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when an action potential arrives at the neuromuscular junction, the most immediate result is   show
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if a muscle is applied to a load that exceeds the muscle's maximum tension   show
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graded muscle response   show
🗑
show most efficient means of producing ATP  
🗑
show muscle would remain in a contracted state due to an inability to break actin-myosin cross bridges  
🗑
show calcium-calmodulin  
🗑
skeletal muscle relies on the __ __ system to regulate contraction   show
🗑
show progressive, wavelike contractions that move foodstuffs through alimentary tube organs/move other substances through other hollow body organs  
🗑
show specific NMJs  
🗑
show innervating nerve fibers, part of autonomic nervous system  
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varicosities   show
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show wide synaptic cleft in general area of smooth muscles  
🗑
show less developed  
🗑
show sarcolemma; half-triads  
🗑
show caveolae  
🗑
when calcium channels in caveolae open, Ca2+   show
🗑
in smooth muscles, SR does release some calcium that triggers contraction, but most   show
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show actively transported to SR & out of cell  
🗑
smooth muscles contain   show
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in smooth muscle, __ filament are fewer, but have __ __ along their entire length   show
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in smooth muscle, there is no __ __ in thin filaments   show
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in smooth muscle, thick & thin filaments are __ __ allowing muscles to contract in __ __; thus peristalsis   show
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show intermediate; dense bodies  
🗑
cytoplasmic structures; tethered to sarcolemma; act as anchoring points for thin filaments; correspond to Z discs of skeletal muscles   show
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forms strong, cable-like intracellular cytoskeleton that harnesses pull generated by sliding of thick & thin filaments in smooth muscles   show
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dense bodies, of smooth muscles, bind muscle cell to   show
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synchronizistic contraction of smooth muscles reflects   show
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show gap junctions  
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some smooth muscles in stomach & small intestines are   show
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show membrane potentials; self-excitatory  
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smooth muscle's pacemaker cells __ __ in absence of stimuli   show
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show neural & chemical stimuli  
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in order to phosphorylate myosin, calmodulin interacts with   show
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smooth muscle takes 30x longer to   show
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show latch together  
🗑
show latch state  
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__ __ of smooth muscle is extremely important to overall body homeostasis   show
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show smooth muscle tone  
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show aerobic pathways  
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show graded potentials  
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smooth muscles react to __ __ in different ways depending on receptors present   show
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show spontaneously; G protein-linked  
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certain hormones, lack of O2, histamine, excess CO2, & low pH are different chemical factors that cause smooth muscle contraction & relaxation   show
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show stretch  
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show shorten  
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stretch of smooth muscle provokes contraction, but soon muscle   show
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show generate considerable force, even when they are substantially stretched  
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smooth muscle can contract when it is anywhere from   show
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show single-unit or multiunit  
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show visceral muscle  
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visceral muscle is also known as   show
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visceral muscle is found in walls of all hollow organs except   show
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smooth muscles in large airways to lungs & in large arteries, arrector pili muscle attached to hair follicles, & internal eye muscles are examples of   show
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in multiunit smooth muscle   show
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multiunit smooth muscle is innervated by   show
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embryonic mesoderm cells from which all muscle fibers develop   show
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