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Muscle tissue

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
show posture  
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show stabilize  
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skeletal muscles generate __   show
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skeletal muscles __ __ but tires easily   show
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show organ composed of muscle tissue, blood, & connective tissue  
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show cardiac muscle  
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show heart’s pacemaker  
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show allow heart to respond to changes in body needs  
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spindle-shaped cells w/1 centrally located nucleus; no externally visible striations; involuntary; forces food, feces & other substances through internal body channels   show
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smooth muscles are found   show
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ability to recoil & resume resting length after being stretched   show
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ability to be stretched/extended   show
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show contractility  
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ability to respond to stimuli   show
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most skeletal muscles __ __ & are attached to bone in at least __ places   show
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show muscle’s origin  
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epimysium of muscle is fused to periosteum of a bone/perichondrium of cartilage   show
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show indirect attachment  
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show endomysium  
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show perimysium  
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dense irregular connective tissue that surrounds entire muscle   show
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show plasma membrane os muscle cell  
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show muscle fiber  
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show cytoplasm of muscle cell  
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contains glycosomes & myoglobin; abundant mitochondria; usual organelles   show
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show cytoplasm  
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made of hundreds of myofibrils   show
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found within myofibril   show
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striations of myofibril are due to   show
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sarcomere is region of myofibril between 2   show
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banding pattern produced by thick myosin & thin actin filaments   show
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show actin  
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thick myofilaments composed of protein   show
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each myosin molecule has   show
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show tails  
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form cross bridges, found in myosin molecules   show
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subunits of thin myofilaments contain active sites to which   show
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show tropomyosin & troponin  
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show endoplasmic reticulum  
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show perpendicular cross channels  
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show calcium ions  
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show T tubules  
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show triads  
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upon __ __, myosin heads bind to active sites on actin & sliding begins   show
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show slide past; overlap  
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show relaxed state  
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show shorten; shortens  
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stimulated by a nerve ending; electrical current or action potential is propagated along its sarcolemma; results in a rise in intracellular Ca2+ levels   show
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the final trigger for skeletal muscle contraction   show
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show excitation-contraction coupling  
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show motor neurons  
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show axons  
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each __ __ forms a neuromuscular junction w/muscle fiber   show
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axon branch; folds of sarcolemma at motor end plate w/acetyl choline receptors; synaptic vesicles in axon terminal; synaptic cleft; are all components of a(n)   show
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__ __ reaches axon terminal at NMJ   show
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at NMJ, voltage-gated __ __ in axon terminal open, allowing __ enter axon   show
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at NMJ, Ca++ inside axon terminal causes synaptic vesicles to fuse with __ __   show
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show exocytosis  
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at NMJ, binding of ACh to its receptors on sarcolemma opens Na/K __ __   show
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show action potential in muscle  
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show enzyme  
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predominant extracellular ion is Na+; predominant intracellular ion is K+   show
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in resting cell inside of sarcolemma is   show
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difference in charge of sarcolemma, negative compared to outside, is known as   show
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show ACh binds to its receptors on sarcolemma Na/K channels open  
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show less negative  
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change in resting potential is   show
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show end plate potential  
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show action potential/propagation  
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if action potential initiated, voltage-gated Na+ channels open in adjacent areas of sarcolemma causing it to   show
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show across sarcolemma  
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show contraction of a muscle  
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show changes  
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in action potential/repolarization, Na+ channels __ & K+ channels __   show
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show diffuses; resting  
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occurs in same direction as depolarization   show
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in excitation/contraction coupling, action potential propagates   show
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show Ca2+ release from terminal cisternae  
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show troponin; exposed  
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show cross bridge; thin filaments  
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show excitation/contraction coupling  
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show active transport  
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stiffening of muscles after death; cross bridge detachment requires ATP   show
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show ATP  
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refers to activation of cross bridges   show
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force exerted by contracting muscle on an object   show
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opposing force exerted on muscle by weight of object   show
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show shortening  
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when cross bridges become inactive, tension declines & relaxation occurs   show
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show isometric contraction  
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isometric contraction is used in   show
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muscle changes in length; muscle tension overcomes load & moves load   show
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isotonic contraction are used in   show
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motor neuron & all muscle fibers it supplies   show
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muscles that control fine precise movements e.g. fingers, eyes (few muscle fibers) have   show
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show large motor units  
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muscle contraction in response to a single stimulus   show
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show latent period  
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phase of a muscle twitch when cross bridges form   show
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show period of relaxation  
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factor affecting muscle tension in which muscle stimulated rapidly, contractions are summed up become stronger   show
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factor affecting muscle tension in which the more the motor fibers are contracting (by recruitment of more motor units) the stronger the contraction   show
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show degree of muscle stretch  
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degree of muscle stretch is optimum muscle length at which they can   show
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show factors that affect muscle tension  
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show a muscle twitch  
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show wave summation  
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show incomplete tetanus  
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smooth continuous contraction without any relaxation   show
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show unstretched sarcomere  
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show overstretched sarcomere  
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maximum tension develops at this optimum overlap of thick & thin filaments; all cross bridges can cycle   show
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show muscle tone  
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muscle tone keeps muscles __ & ready to __ to stimulus   show
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show spinal reflexes  
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ATP in muscle contraction is used for energizing   show
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show detaching  
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show calcium  
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show ATP regeneration  
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show creatine phosphate (CP)  
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during contraction: when muscle contractile activity reaches 70% of maximum, bulging muscles compress blood vessels; impaired O2 delivery   show
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during contraction, largest amount of ATP formed   show
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show muscle fatigue  
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muscle fatigue can be due to __ ATP production   show
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show lactic acid  
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show speed of contraction  
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a functional characteristic of muscle fiber type, according to ATP-forming pathways   show
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cells that rely on oxygen-using aerobic pathways for ATP generation   show
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show glycolytic fibers  
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characteristics intermediate btwn oxidative & glycolytic fibers   show
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red fibers; depend on aerobic ATP production; have more myoglobin, capillaries, mitochondria, low glycogen; contract slowly, are fatigue resistant & have high endurance   show
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example of slow oxidative fibers   show
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white fibers; mainly use glycolysis for ATP production; large diameter fibers, have abundant glycogen, but few capillaries, mitochondria & low myoglobin; contract quickly, and are easily fatigued; muscles used for short time in powerful activities   show
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example of fast glycolytic fibers   show
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show mixture  
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shrinkage of muscle due to decrease in size of cells   show
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example of disuse atrophy   show
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example of atrophy due to loss of nerve supply   show
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show hypertrophy  
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show strenuous exercise in body builders  
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show smooth muscle  
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show walls of blood vessels, digestive, urinary, respiratory & reproductive tracts  
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show sheets  
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organized sheets of smooth muscle are sheets of   show
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show structures neuromuscular  
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show varicosities  
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show less developed  
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smooth muscle T tubules are   show
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in smooth muscle, actin & myosin filaments are present but   show
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in smooth muscle, there is no   show
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show smooth muscle contraction  
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mostly whole sheets of smooth muscle contract together, because of __ __, as __ __ spread from cell to cell   show
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each skeletal muscle fiber is stimulated to __ by its own NMJ   show
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show sliding filament mechanism  
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in smooth muscle, final trigger for contractions is a(n)   show
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in smooth muscle, sliding filament mechanism   show
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show extracellular space  
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in smooth muscle, some Ca2+ is __ __ SR   show
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show cardiac & skeletal muscles  
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show increased contraction  
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enables organs such as the stomach and bladder to be able to store contents without strong contractions expelling contents   show
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show smooth muscle single unit  
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show smooth muscle multiunit  
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increase in cell numbers   show
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smooth muscles can undergo hyperplasia   show
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show estrogen’s effect on the uterus  
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show smooth muscle hyperplasia  
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because skeletal & smooth muscles are __ they are called muscle fibers   show
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show muscle  
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word root means muscle   show
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show sarco-  
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word root means husk   show
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muscle composed of cylindrical, multinucleate cells w/obvious striations; attached to skeleton; voluntary muscle   show
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show skeletal muscles  
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show heart walls  
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show neural controls  
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response to stimuli; generation of electrical impulse that passes along plasma membrane of muscle cell & causes cell to contract   show
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produces movement, maintains posture, stabilizes joints, generates heat, etc.   show
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show locomotion; manipulation  
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skeletal muscles enable you to __ __ to changes in external environment   show
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cardiac muscle of heart & smooth muscle in walls of blood vessels help to   show
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skeletal muscles account for at least 40% of   show
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show generating heat  
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show smooth muscles  
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show composition of skeletal muscles  
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in general, __ __ is served by one nerve, artery, & 1/more veins   show
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show contract in without nerve stimulation  
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long & winding w/numerous cross-links, which is feature that accommodates changes in muscle length   show
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muscle capillaries __ when muscle is stretched   show
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show contort  
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support each muscle cell & reinforce muscle as a whole; prevents bulging muscle from bursting during strong contractions   show
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bundle of nerve/muscle fibers bound together by CT   show
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show elasticity  
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CT sheaths provide entry & exit routes for   show
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movable attachment of a muscle   show
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when muscle contracts movable bone, __ moves towards immovable/less movable bone   show
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cord of dense fibrous tissue attaching muscle to bone   show
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fibrous/membranous sheet connecting muscle & part it moves   show
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show aponeurosis/tendon  
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indirect attachments are more common because of   show
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show tendons; joint  
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show glycosomes  
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oxygen-binding, red pigment in muscle   show
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show hemoglobin  
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show myofibril  
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myofibrils account for about 80% of   show
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repeating series of dark & light bands, evident along length of each myofibril   show
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show A bands  
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show I bands  
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show H zone  
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show M line  
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darker, midline interruption in I bands; coin-shaped sheet composed largely of protein alpha-actinin; anchors thin filaments   show
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smallest contractile unit of muscle; extends from 1 Z disc to next   show
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show functional unit  
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sarcomere contains __ band flanked by 1/2 __ band   show
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located in center; contain myosin; extend entire length of A band   show
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more lateral; contain actin; extend across I band & partway into A band   show
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contain desmin; extend from Z disc; connect each myofibril to next throughout width of muscle cell   show
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consists of 2 heavy & 4 light polypeptide chains; has rod-like tail attached by flexible hinge to 2 globular heads   show
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rod-shaped protein, spiral about actin core & hep stiffen & stabilize it   show
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show block  
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globular, three-polypeptide complex   show
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troponin & tropomyosin help control __ __ involved in contraction   show
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composed of titin   show
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show titin  
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titin forms __ of thick filament   show
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show organization of A band  
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titin holds thick filaments in place, helping muscle cell to   show
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titin does not resist stretching in   show
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titin stiffens as it uncoils, helping muscle to   show
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structural protein that links thin filaments to integral proteins of sarcolemma   show
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show bind filaments or sarcomeres together & maintain their alignment  
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show participate in regulation of muscle contractions  
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show myofibril communicating at H zone  
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major role of SR is to regulate   show
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T tubules increase muscle fiber's __ __   show
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successive groupings of 2 membranous structures (terminal cisterna, T tubule, & terminal cisterna   show
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show conduct impulses to deepest regions of muscle cell to every sarcomere  
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protruding integral proteins of T tubules act as   show
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show foot proteins  
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show activation of myosin's cross bridges  
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states that during contraction thin filaments slide past thick ones so that actin & myosin filaments overlap to greater degree   show
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for skeletal muscle to contract it must be   show
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large transient depolarization event, including polarity reversal, that is conducted along membrane of muscle cell/nerve fiber   show
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for skeletal muscle to contract it must be activated, then must   show
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show short-lived rise in intracellular calcium ion levels  
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show somatic motor neurons  
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show axons  
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synaptic connection of axon of motor neuron with muscle fiber   show
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show elliptical neuromuscular junctions  
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each muscle fiber has   show
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show synaptic cleft  
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show acetylcholine (ACh)  
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show junctional folds  
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junctional folds provide __ __ __ for location for millions of ACh receptors   show
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neuromuscular junction includes   show
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enzyme present at NMJ & synapses that degrades acetylcholine & terminates its action   show
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disease characterized by drooping upper eyelids, difficulty swallowing & talking, & generalized muscle weakness, involves shortage of ACh receptor   show
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show polarized  
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loss of a state of polarity; loss/reduction of negative membrane potential   show
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depolarizations of skeletal muscle fibers caused by neurotransmitters binding to post-synaptic membrane in NMJ   show
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movement of membrane potential to initial resting state   show
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show refractory period  
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show electrical conditions  
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ATP-dependent sodium-ion pump restores __ __ of resting state   show
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once initiated, the action potential is __   show
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events of excitation-contraction coupling take place during __ __ btwn action potential initiation & beginning of mechanical activity   show
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show muscle is relaxed  
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show removed  
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continues as long as Ca signal & adequate ATP are present   show
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show increase greatly  
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except for brief period following muscle cell __, Ca ion concentrations in cytosol are kept low   show
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graphic recording of mechanical contractile activity produced by apparatus that measures muscle contraction   show
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show period of time btwn stimulation & onset of muscle contraction; excitation-contraction coupling occurs here  
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show when cross bridges are active, from onset-peak tension development, myogram tracing rises to peak  
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period of relaxation   show
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show some neuromuscular problems  
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relatively smooth; vary in strength as different demands placed on them   show
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show graded muscle responses  
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nervous system achieves __ __ __ by increasing firing rate of motor neurons   show
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show temporal/wave summation  
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show unfused/incomplete tetanus  
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show complete tetanus  
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fused/complete tetanus happens __ in real world   show
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__ tetanus eventually leads to muscle __   show
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show contractile  
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show primary function of wave summation  
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show recruitment/multiple motor unit summation  
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stimulus too weak to evoke a response   show
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show threshold stimulus  
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show maximal stimulus  
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show does not produce stronger contraction  
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recruitment process is __ by size principle   show
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motor units of small, highly excitable motor neurons (found in smallest muscle fibers) tend to be activated first; as motor units w/larger & larger muscle fibers begin to excited, contractile strength increases   show
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show most powerful contraction is necessary  
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show occur in small steps  
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according to size principle, gradations in muscle force are __ __ when large amounts of force are needed   show
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show asynchronously  
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even __ muscles are almost always __   show
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show concentric contraction  
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type of muscle contraction that occurs as muscle fibers lengthen; contractile force generated by muscle is weaker than opposing force, which causes muscle to stretch   show
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show more forceful  
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eccentric contractions put body in position to   show
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CP-ADP reaction is catalyzed by   show
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show glycolysis  
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show per glucose broken down  
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product of anaerobic metabolism, especially in muscle   show
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lactic acid is produced when bulging muscles (from vigorous activity) compress blood vessels within them causing   show
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energy-yielding conversion of glucose to lactic acid in muscle, when sufficient oxygen is not available   show
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during __ __, lactic acid is end product of cellular metabolism of glucose   show
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95% of ATP used for muscle activity from from   show
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when ATP demands are within capacity os aerobic pathway, light to moderate muscular activity can   show
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show glycolysis contributes more & more of total ATP generated  
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show aerobic endurance  
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show anaerobic threshold  
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activities requiring surge of power lasting only few seconds (i.e. weight lighting, diving, etc.) rely   show
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more on-and-off or burst-like activities (i.e. tennis, soccer, etc.) appear to be fueled   show
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show mainly on aerobic respiration  
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levels of CP & ATP do not change much during __ __ because ATP is generated at same rate it is use   show
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show contractures  
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example of temporary contracture   show
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show ionic imbalances  
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lactic acid is more important in provoking __ fatigue than __ fatigue   show
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show contractile proteins  
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lactic acid has been shown to __ high K+ levels, which do lead to muscle fatigue   show
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show alter E-P coupling  
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show regulation; release  
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show anaerobic muscle contraction  
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show oxygen deficit (definition)  
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show need; actually used  
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only about 40% of energy released during muscle activity is   show
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show cross-sectional area  
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force generated by cross bridges, inside contracting muscle fibers   show
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show external tension  
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show optimal operating length  
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relationship btwn length of fiber & force that fiber produces at that length; permits sliding along nearly entire length of thin filaments   show
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show split ATP  
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in slow/fast fibers, difference in speed reflects on pattern of __ __ of motor neurons   show
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depending on pathways for forming ATP, skeletal muscles cells can be classified as   show
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exercise that increases the need for oxygen   show
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moderately weak but sustained muscle activity   show
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high-intensity exercise in which the muscles are pitted against high resistance or immovable forces and, as a result, muscle cells increase in size   show
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smooth muscle fibers run parallel to long axis of organ; when muscle contracts organ dilates & shortens   show
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show circular layer  
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junction of varicosities & synaptic cleft of smooth muscle cells   show
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show surround entire muscle  
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endomysium   show
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perimysium   show
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deep fascia   show
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show plasma membrane of skeletal muscle fiber  
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show cytoplasm of a skeletal muscle fiber  
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sarcoplasmic reticulum   show
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show rod-like contractile elements within a muscle fiber  
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show functional unit of a skeletal muscle fiber  
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show area of the sarcomere with overlapping thick and thin filaments  
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show area of sarcomere containing only thin filaments  
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show are in center of A band containing only thick filaments  
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show cross bridges  
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synaptic knob   show
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synaptic cleft   show
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motor end plate   show
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twitch   show
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show muscle producing peak tensions with visible relaxation during rapid cycles of contraction and relaxation  
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show muscle that is stimulated so frequently that the relaxation phase is completely eliminated  
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wave summation   show
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show best suited for slow oxidative fibers  
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400M or 800M sprint   show
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short-term intense movements   show
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show single, very long, cylindrical, multinucleate cells with striations  
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show branching chains of cells; uni- or binucleate striations; intercalated discs  
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show single, fusiform, uninucleate; no striations  
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show ability to receive and respond to a stimulus  
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contractility   show
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show ability to be stretched or extended  
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elasticity   show
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show contraction of muscle during which the muscle changes in length and the tension remains constant through most of the contractile period  
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isometric contraction   show
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show contraction of the muscle in which the muscle shortens and does work  
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show contraction of muscle in which the muscle contracts as it lengthens  
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show axonal endings  
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show cardiac muscles  
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involuntary, autonomic nerves, hormones, local chemicals   show
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show neurotransmitter at the neuromuscular junction  
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show high-energy compound in muscle  
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show O2 storage molecules in muscles  
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lactic acid   show
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fast oxidative fibers   show
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show muscle fibers that are most resistant to fatigue  
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show muscle fibers that have few mitochondria  
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sustained spasm, or tetanic contraction   show
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inflammation of a muscle, its connective tissue coverings and tendons, and capsules of nearby joints   show
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show myalgia  
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excessive stretching and possible tearing of a muscle caused by muscle overuse or abuse   show
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show time btwn stimulus/electrical event & mechanical event of contraction  
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show time during which the muscle is shortening  
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show time during which the muscle is returning to its original length  
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refractory period   show
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action potential   show
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resting potential   show
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repolarization   show
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refractory period   show
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show electrical event occurring only at neuromuscular junction  
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show released by terminal cisternae into the sarcoplasm to bind with troponin  
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acetylcholinesterase   show
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calmodulin   show
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electrical conditions of a resting sarcolemma   show
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depolarization & generation of action potential   show
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propagation of action potential   show
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show change in sarcolemma after the wave of depolarization; Na+ channels close and K+ channels open, allowing K+ to create a positive charge outside the membrane  
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producing movement   show
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maintaining posture   show
🗑
show attaching to bones and keeping them in close proximity to one another  
🗑
show release of energy during metabolism  
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show changes shape during the contraction cycle  
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actin   show
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tropomyosin   show
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show binds Ca2+ and starts the contraction cycle  
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show entire  
🗑
as an axon enters a muscle, it branches into a number of axonal terminals, each of which forms a neuromuscular junction with a single muscle fiber. A motor neuron and all the muscle fibers it supplies is called a(n)   show
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show Ca2+  
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each skeletal muscle fiber is controlled by a neuron at a single   show
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show composition of the structure known as a triad in a skeletal muscle fiber  
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show sliding filament model  
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show dense layer of collagen fibers that surround an entire skeletal muscle  
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muscle tone   show
🗑
show type of muscle contraction in which the muscle fibers produce increased tension, but the muscle neither shortens nor lengthens  
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lactic acid   show
🗑
show sequence of electrical changes that occurs along the sarcolemma when a muscle fiber is stimulated  
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show binds calcium ions in a smooth muscle, causing contraction  
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sarcomere is part of   show
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"cross bridges" that link between the thick and thin filaments are formed by the   show
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show refractory period of muscle cell  
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cause of rigor mortis   show
🗑
95% of the energy needed for contraction during moderate exercise   show
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T-tubules   show
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actin   show
🗑
show release of acetylcholine  
🗑
if a muscle is applied to a load that exceeds the muscle's maximum tension   show
🗑
graded muscle response   show
🗑
aerobic respiration   show
🗑
show muscle would remain in a contracted state due to an inability to break actin-myosin cross bridges  
🗑
show calcium-calmodulin  
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skeletal muscle relies on the __ __ system to regulate contraction   show
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show progressive, wavelike contractions that move foodstuffs through alimentary tube organs/move other substances through other hollow body organs  
🗑
show specific NMJs  
🗑
smooth muscles are controlled by   show
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varicosities   show
🗑
show wide synaptic cleft in general area of smooth muscles  
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show less developed  
🗑
show sarcolemma; half-triads  
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pouch-like infoldings that sequester bits of extracellular fluid containing high concentration of Ca2+ close to membrane   show
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when calcium channels in caveolae open, Ca2+   show
🗑
show enters through the calcium channels  
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contraction of smooth muscle ends when calcium is   show
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show interdigitating thick & thin filaments  
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show thick; myosin heads  
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show troponin complex  
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in smooth muscle, thick & thin filaments are __ __ allowing muscles to contract in __ __; thus peristalsis   show
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in smooth muscles, the lattice-like arrangement of non-contractile __ filaments attach to __ __   show
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show dense bodies  
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forms strong, cable-like intracellular cytoskeleton that harnesses pull generated by sliding of thick & thin filaments in smooth muscles   show
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show endomysium & adjacent cells  
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show electrical coupling by gap junctions  
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allow smooth muscles to transmit action potentials from fiber to fiber   show
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show pacemaker cells  
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smooth muscle's pacemaker cells have fluctuating __ __ & are __   show
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show depolarize spontaneously  
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rate & intensity of smooth muscle contraction may be modified by   show
🗑
show myosin kinase/myosin light chain kinase  
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show contract & relax than skeletal muscle  
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show latch together  
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show latch state  
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show ATP-efficient contraction  
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show smooth muscle tone  
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show aerobic pathways  
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show graded potentials  
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show different neurotransmitters  
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smooth muscles without nerve supply depolarize __ or in response to chemical stimuli that bind to __ __ receptors   show
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show without an action potential  
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show stretch  
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smooth muscle can __ more than other muscle types   show
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show adapts to length & relaxes with retaining ability to contract on demand  
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lack of sarcomeres & irregular, overlapping arrangement of smooth muscle filaments allow them to   show
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smooth muscle can contract when it is anywhere from   show
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show single-unit or multiunit  
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type of smooth muscle; cells contract as unit & rhythmically, are electrically coupled by gap junctions; often exhibit spontaneous action potentials   show
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show single-unit smooth muscle  
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show the heart  
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show multiunit smooth muscle  
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in multiunit smooth muscle   show
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show autonomic nervous system  
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show myoblasts  
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