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Homework Packet #6

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Question
Answer
A chemical that prevents blood _______________ is an anticoagulant.   Coagulation  
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An artery is a large blood vessel that carries _______________ blood from the heart to the tissues.   Oxygenated  
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The hemoglobin formed when oxyhemoglobin releases oxygen to the tissues is known as _______________.   Deoxyhemoglobin (deoxygenated)  
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_______________ is a condition in which the RBC count or hemoglobin level is decreased below normal.   Anemia  
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The anticoagulant EDTA is commonly used in _______________ studies.   Hematology  
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The study of _______________ and _______________ tissues is called hematology.   Blood/Blood-forming  
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_______________ is the liquid portion of blood in which the cellular elements are suspended.   Plasma  
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A ________________ is also know as a leukocyte.   WBC - White blood cell  
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In _______________, most blood cells are formed in the bone marrow.   Adults  
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A glass or plastic tube of very small diameter used for laboratory procedures is called a ________________ tube.   Capillary  
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The ________________ is a commonly performed test that provides the clinician with an estimate of the patient's red cell volume and the blood's oxygen-carrying capacity.   Hematocrit  
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The _______________ is a light-colored layer of leukocytes and platelets that forms on the top of the red blood cell layer when a sample of blood is centrifuged or allowed to stand undisturbed.   Buffy coat  
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An instrument that spins capillary tubes at high speed is called a _______________ centrifuge.   Microhematocrit (or Microfuge)  
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The packed cell volume is another term used for _______________.   Hematocrit  
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Capillary blood for a microhematocrit should be collected in _______________ capillary tubes.   Heparinized  
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The protein portion of the hemoglobin molecule is the _______________.   Globin (Globin chains)  
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Hemoglobin is the main constituent of _______________.   RBC's or Erythrocytes  
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_______________ is the iron-containing portion of the hemoglobin molecule.   Heme  
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The major functional component of RBCs, _______________ serves as the oxygen-carrying molecule.   Hemoglobin  
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The form of hemoglobin that is called "adult" hemoglobin is Hgb _______________.   A (A1 or A2)  
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Hemoglobin transports _______________ from the tissues to the lungs.   Carbon Dioxide (CO2)  
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The mineral required for hemoglobin synthesis is _______________.   Iron (Fe)  
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Peripheral blood cells, bacteria, cells in cerebrospinal fluid, and sperm can be counted microscopically by using the _______________.   Hemacytometer (Counting Chamber)  
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In light scatter, the laser light is monochromatic, meaning that it has only one _______________.   Wavelength  
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All electrical impedance cell counters are based on the principles of _______________, and an _______________ is a solution in them that conducts an electrical current.   Coulter's/Electrolyte  
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A _______________ is a graph that illustrates the size and frequency of articles in solution.   Histogram  
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In electrical impedance instruments, an electrical current flows from one electrode to another across the _______________.   Aperture  
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Flow cytometers combine principles of light scatter with the light excitation and emission of _______________ signals.   Fluorescent  
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PLATELET   A formed element in circulating blood that plays an important role in blood coagulation.  
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BAND CELL   An immature granulocyte with a non-segmented nucleus.  
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ANISOCYTOSIS   A marked variation in the size of erythrocytes when observed on a peripheral blood smear.  
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BASOPHILIA   An abnormal increase in the number of basophils in the blood.  
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MCHC - Mean Cell Hemoglobin Concentration   Comparison of the weight of hemoglobin in a red blood cell to the size of the red blood cell, expressed in percentage or g/dL.  
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RETICULOCYTE   An immature erythrocyte that has retained RNA in the cytoplasm.  
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OXYHEMOGLOBIN   The form of hemoglobin that binds and transports oxygen.  
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THROMBOCYTE   A blood platelet.  
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PCV - PACKED CELL VOLUME   The layers of blood cells that form when a tube of whole blood is centrifuged.  
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LEUKOPENIA   A decrease below normal in the number of leukocytes in the blood.  
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WRIGHT'S STAIN   A combination of eosin and methylene blue in methanol; a polychromatic stain.  
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VACUOLE   A membrane-bound compartment in cell cytoplasm.  
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POIKILOCYTOSIS   Significant variation in the shape of erythrocytes.  
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MCH - Mean Cell Hemoglobin   Average red blood cell hemoglobin expressed in picograms [pg].  
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TARGET CELL   Abnormal red blood cell with target appearance; a codocyte.  
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SEDIMENTATION   The process of solid particles settling to the bottom of a liquid.  
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LASER   A narrow, intense beam of light of only one wavelength going in only one direction.  
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CYTOPLASM (CYTOSOL)   The fluid portion of the cell surrounding the nucleus.  
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BASOPHIL   A leukocyte containing basophilic-staining granules in the cytoplasm.  
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ATYPICAL LYMPHOCYTE (REACTIVE)   A lymphocyte that occurs in response to viral infections and that is common in infectious mononucleosis.  
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BASOPHILIC STIPPLING   Remnants of RNA and other basophilic nuclear material remaining inside the erythrocyte after the nucleus is lost from the cell and which appear as small purple granules in stained red blood cells.  
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MCV - MEAN CELL VOLUME   The average red blood cell volume in a blood sample, expressed in femtoliters (fL) or cubic microns (µm^3 or µ^3)  
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INFLAMMATION   A nonspecific protective response to tissue injury.  
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HEME   The iron-containing portion of the hemoglobin molecule.  
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EOSIN   A red-orange stain or dye used in hematology.  
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DIFFERENTIAL COUNT   A determination of the relative numbers of each type of leukocyte.  
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BLAST CELL   An immature blood cell normally found only in the bone marrow.  
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NUCLEATED BLOOD CELL   A red blood cell that has not yet lost its nucleus.  
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ROULEAUX   Groups of red blood cells arranged like a roll of coins.  
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HEMOSTASIS   The process of stopping bleeding, which includes clot formation and dissolution.  
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MEGAKARYOCYTE   A large bone marrow cell from which platelets are derived.  
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IMMUNITY   Resistance to disease or infection.  
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LEUKOCYTOSIS   An increase above normal in the number of leukocytes in the blood.  
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POLYCHROMATIC   Having many colors.  
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EOSINOPHIL   A leukocyte containing eosinophilic granules in the cytoplasm.  
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NEUTROPHIL   A neutral-staining leukocyte; usually the first line of defense against infection.  
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PHAGOCYTOSIS   The ingestion of a foreign particle or cell by another cell.  
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ERYTHROCYTE INDICES (MCV, MCH & MCHC)   Calculated values that compare the size and hemoglobin content of red blood cells in the blood sample to reference values.  
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IMPEDANCE   Resistance to an electrical circuit.  
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MORPHOLOGY   The form and structure of cells, tissues, and organs.  
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MONOCYTE   A large leukocyte usually having a convoluted or horseshoe-shaped nucleus.  
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SHIFT TO THE LEFT   The appearance of an increased number of immature neutrophil forms in the peripheral blood.  
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GRANULOCYTE   Any of the neutrophilic, eosinophilic, or basophilic leukocytes.  
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RNA   A nucleic acid that is important in protein synthesis and that is found in all living cells.  
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