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Terms from Regulation unit at NW 04-350

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Term
Definition
show some substance in the environment responsible for triggering a change in gene expression. Could be chemical substance, radiation, temperature, pH, or environmental condition  
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show gene that is coding for a metabolic enzyme or protein used to build a structure  
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show genes that are always being expressed, and therefore not regulated, are constitutively expressed  
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housekeeping genes   show
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show protein or RNA that influences the expression of other genes by binding to the regulatory element. may influence transcription or translation. trans acting  
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show nucleic acid sequence (DNA or RNA) which the regulatory product attaches, influencing the expression of genes physically connected to the element. cis acting  
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show when a genes expression is stimulated by binding of regulatory product to the regulatory element, but expression is turned off when they do not bind  
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negative control   show
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show a regulatory product responsible for positive control  
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repressor   show
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show when gene expression is stimulated by the presence of an environmental signal  
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repressible   show
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inducer   show
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show system of regulation common in prokaryotes. involves multiple genes coding for proteins involved in the same biochemical process sharing a single promoter and regulatory element. when one gene is expressed all are expressed. produces a polycistronic mRNA  
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promoter   show
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show common term for a regulatory element adjacent to the promoter. binding site for a regulatory product  
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lac operon   show
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Lac Z   show
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show gene coding for permease, transporter protein used to move lactose into the interior of the cell from the external environment  
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Lac A   show
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Lac I   show
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catabolite activator protein (CAP)   show
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cAMP   show
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antisense RNA   show
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riboswitch   show
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chromatin structure   show
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acetylation   show
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show removal of an acetyl group  
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sex lethal (sxl)   show
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gal4   show
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gal80   show
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show repressor of the repressor gal80... therefore an activator. prevents gal80 from blocking contact between gal4 and the mediator. responds to galactose concentration as an environmental signal  
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upstream activation sequence (UAS)   show
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western hybridization   show
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show technique used to measure the amount of RNA present by binding a labelled DNA probe to an RNA  
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show immunoglobulin that recognizes the 3d shape of a protein (epitope) and is able to bind  
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secondary antibody   show
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hybridization   show
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microarray   show
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reverse transcriptase   show
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show gene whose protein product is easily detectable (enzymatic reaction, light production etc). often attached to regulatory element and used to make transgenic organisms to identify where expression of a gene would normally occur  
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transgenic organism   show
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Created by: jthorns
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