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Terms from Translation unit of 04-350 at NW

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Term
Definition
show monomeric subunit used to form a polypeptide or protein  
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show NH3+, functional group that is part of an amino acid. You could consider this the head of the monomer.  
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carboxyl group   show
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variable group   show
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radical group   show
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alpha carbon   show
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show covalent bond that links amino acids together in a chain, extending from the carboxyl group of the first amino acid to the amino acid of the second. formed by peptidyl transferase during translation  
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show a nucleoside that may be found in RNA after chemical modification has occurred. found in the T loop of tRNA  
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dihydroxyuridine   show
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show a nucleoside that may be found in RNA after chemical modification has occurred. found in the anticodon of tRNA in particular  
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show stem loops and hairpins of tRNA due to internal base pairing. greatly influenced by rare chemically modified bases  
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show overall 3D shape of a tRNA when stem loops are twisted and contorted. greatly influenced by rare chemically modified bases. determines which amino acyl synthetase will charge that tRNA  
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anticodon   show
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D loop   show
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show loop of a tRNA closest to the 3' end of the molecule. Contains a thymidine due to chemical modification  
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show Loop of a tRNA that may or may not be present. Has a big impact on overall shape  
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acceptor stem   show
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show process by which amino acids are attached to the acceptor stem of a tRNA. Requires the consumption of energy.  
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amino acyl tRNA synthetase   show
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codon   show
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triplet   show
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show one codon sequence always codes for the same amino acid  
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show a single base in a codon is part of only one codon... not multiple  
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show the genetic code is not broken up using markers to distinguish one codon from the other  
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redundant   show
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universal   show
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start codon   show
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show a sequence in the mRNA that indicates where translation will stop. not recognized by any tRNA but recognized by release factors instead. also known as nonsense codons  
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ORF   show
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show a codon that codes for an amino acid  
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show possibility of improper complementary base pairing that violates Chargaff's Rules, of A-U, and C-G pairing. Possible but not thermodynamically stable. Occurs during mutation and wobble.  
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wobble   show
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Svedberg unit   show
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show machinery for protein synthesis, composed of two subunits (one large and one small)  
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small ribosomal subunit   show
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show complex of rRNA and protein that serves as one half of a functional ribosome  
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A site   show
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P site   show
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show exit site, exit channel where uncharged tRNA will leave the ribosome after being used in translation  
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show portion of the large ribosomal subunit that makes contact with elongation factors to insure the proper tRNA is in the A site  
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show ribozyme that is part of the large ribosomal subunit, responsible for making the peptide bonds between amino acids during translation  
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show 5' untranslated region, portion of the mRNA at the 5' end that does not contain codons, upstream of the start codon  
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3' UTR   show
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show a mRNA that contains a single ORF  
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polycistronic   show
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ribosomal binding site   show
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initiator tRNA   show
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show chemically modified methionine used during initiation of prokaryotic translation carried by the initiator tRNA  
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Methionine   show
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IF1   show
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show initiation factor 2, protein in prokaryotes that holds the initiator tRNA in place until the ribosome assembles  
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show initiation factor 3, protein in prokaryotes that keeps lrge and small ribosomal subunits apart until they recognize a mRNA  
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GTP   show
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methyl guanosine cap   show
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show consensus sequence found in eukaryotic 5' UTR adjacent to the start codon, used to indicate which start codon should be used for initiation  
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cap binding proteins   show
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EF-Tu   show
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EF-G   show
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release factor   show
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mRNA looping   show
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show alterations to polypeptides after translation has been completed, may include adding sugars or phosphate or removing segments of amino acids  
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Created by: jthorns
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