Teratology Test.
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| What area of the body has a critical period of 3 weeks to term? | CNS
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| What area of the body has a critical period of 3 weeks to 8 weeks? | Heart
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| What area of the body has a critical period of 4 weeks to 8 weeks? | Upper and Lower Limbs
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| What area of the body has a critical period of 4 weeks to 20 weeks? | Ear
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| What area of the body has a critical period of 4 weeks to term? | Eyes
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| What area of the body has a critical period of 6 weeks to 16 weeks? | Palate
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| What area of the body has a critical period of 6 weeks to term? | Teeth
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| What area of the body has a critical period of 7 weeks to term? | External Genitalia
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| What are the 3 FDA guidelines | 1) Fertility and General Reproductive performance, 2) Teratological Study, 3) Perinatal and Postnatal studies.
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| St. John's Wart causes? | Pregnancy, contradicts oral contraceptives
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| SSRIs (prozac, zoloft, celexa, lexapro) cause? | Low risk of anything, may affect motor development.
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| Paxil may cause? | Heart Defects
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| Lithium may cause? | Ebstein's anomaly.
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| Anticonvulsants may cause? | Malformations, OB complications, Hemorrhage, Developmental Delay.
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| Aminopterne & Methotrexate may cause? | Mild MR, craniofacial anomalies
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| ACE inhibitors may cause? | Renal problems, Renal tubular dysplasia, can lead to oligo and Potter's
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| DES may cause? | From week 0 to week 20, Genital anomalies
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| Misoprostol may cause? | From the 6th week to the 8th week, Limb reduction, Moebius sequence, CNS anomalies
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| Accutane may cause? | From 15th day to 1st trimester, CNS, Ear, Heart
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| Streptomycin may cause? | Perceptive hearing loss
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| Tetracycline may cause? | After the 4th month, Defects in primary teeth.
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| Thalidomide may cause? | 34-50 days after LMP, Phocomelia, Amelia
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| Warfarin may cause? | 6th to 9th week, Seziures, hypoplasia of nose
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| Retinoic Acid may cause? | 3rd through the 5th week, Crainofacial, Cleft palate, NTD, Heart
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| Valporic Acid may cause? | Spinal Tube defects
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| Alcohol may cause? | Miscarriage, FAS
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| Tobacco may cause? | IUGR, Prematurity, stillbirth
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| Cocaine may cause? | SIDS
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| Methylmercury may cause? | CNS
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| Rubella may cause? | Cataracts, Heart, deafness, MR
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| CMV may cause? | Hepatosplenomegaly, Microcephaly, Cerebral calcification
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| Herpes may cause? | IUGR, Microcephaly
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| Varicella may cause? | 8th to 20th week exposure, Scarring, Limb hypoplasia, IUGR,
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| 5th disease/Parvovirus B-19 may cause? | Minimal Risk, Hydrops
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| Toxoplasmosis may cause? | Hydrocephalus, Chorioretinitis, Hephatosplenomegaly, Deafness/blindess.
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| Questions to ask the patient: | Do you drink, how much? Do you smoke, how much? Do you take any OTC drugs, which? Do you use any illegal substances, which? Have you had X-Rays since you've been pregnant? Are you epileptic? Do you have high blood pressure, take ACE inhibitors?
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| What causes Cleft Lip/Palate? | Anti-seizure/anticonvulsant medications, acne medications containing Accutane, and methotrexate, Glucticosteriods
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| What drugs can cause CHD? | Antipsychotic drugs, Anticonvulsants
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| What drugs cause Meningomyelocele? | Anticonvulsants.
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| How much Folic Acid should a pregnant women have in her diet? | 0.4mg daily
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| How much Folic Acid should a pregnant women who already had a child with ONTD have in her diet? | 2-4mg daily.
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Created by:
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