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Gastroenterology

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Question
Answer
show Diarrhea (often bloody); Fatigue (poss rel to anemia, not nec); wt loss; anorexia; N/V; crampy abdominal pain (d/t obstructive sx?)  
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show Any part of GI tract (most commonly terminal ileum); skip lesions; transmural  
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Features of UC   show
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Specific clinical features of UC   show
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show fistula: abscesses; more common at anus; strictures of the intestine; CRC risk increased if > 1/3 colon involved; smoking & CD: bad  
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show may involve any area; usu eye, skin, liver, and joints (arthralgias, AS)  
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EIM: arthralgia Type 1:   show
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EIM: arthralgia Type 2:   show
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Primary sclerosing cholangitis (PSC)   show
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show erythema nodosum; sx of Crohn dz. May require steroids  
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Pyoderma gangrenosum   show
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IBD eye complications   show
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show infxs diarrhea; ischemia (elderly, PVD, thrombosis); meds (PCN, NSAID, CellCept); diverticular dz; perianal fistula  
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show Combo of endoscopy, histology, radiography, labs & clinical data; Colonoscopy with ileal intubation & bx (should see chronic colitis/enteritis); Small bowel follow-through, enteroclysis (+/- CT), MR enterography  
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show often anemic (Fe def & chronic dz), leukocytosis, elevated CRP (CD); DO NOT ORDER serologies (ASCA, Cbir, OmpC & Crohns; p-ANCA & UC)  
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Genl principles of tx of IBD   show
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show ≤5 BM/day; no sx systemic toxicity; normal ESR  
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show >5 BM/day and <10lb wt loss; no sx systemic toxicity  
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IBD tx options   show
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6MP/AZA MOA:   show
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show CD/UC colitis >1/3 colon: colonoscopies starting 8 yrs from sx onset; q1-3 years; if comorbid PSC: immed start annual colonoscopy; FH also inc CRC risk  
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show necessitate colectomy.  
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show necessitate segmental resection in CD (try to avoid surg if poss in CD)  
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show frequent UTIs/pneumaturia (fistula to bladder); High fever/abd mass (abscess, liver abscess); severe abd pain (perf); N/V (obstruction); severe rectal pain (perirectal abscess)  
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Managing IBD flares   show
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Granulomas on bx are highly suggestive of:   show
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show thickened, matted bowel loops, intra-abdominal abscess  
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show Hourly BMs; toxic appearance, fever, tachy, Hct <25; 10-20lb wt loss  
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Test of choice for UC   show
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Contraindicated in eval of acute UC:   show
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UC treatment   show
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UC tx if intractable:   show
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IBD and smoking   show
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Crohn Dz findings   show
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show wide spectrum of necrotic inflam; IBD tx, topical tx, or poss colectomy; DO NOT Bx  
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IBD eye complications   show
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IBD colon ca risk/surveillance   show
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Pseudopolyps in CD:   show
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Koilonychia =   show
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