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Anatomy- Blood

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Answer
red blood cells   transport(O2) from lungs to tissues &(CO2)from tissue to lungs; 1/3 hemoglobin, 2/3 lipids, ATP, carbonic anhydrase  
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white blood cells   cells that protect the body from foreign microbes and toxins  
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Granulocytes   contain numerous granules in the cytoplasm and have a nucleus that is irregularly shaped with lobes (WBC) Neutro, Eosino, Baso  
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Neutrophils   the first WBCs to arrive at a site of infection, responding (by chemotaxis) to chemicals released by damaged cells.engulf bacteria, which are then destroyed by the various antibiotic proteins contained within the granules (granulocyte); 60-70% of WBC  
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Eosinophils   enter tissue during inflammatory response; allergic reactions; destroyhistamines  
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Basophils   inflammation and allergic response (granulocyte) least common  
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Agranulocytes   (WBC) do not have visible granules in the cytoplasm and the nucleus is not lobed (lympho & mono)  
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Lymphocytes   antibody production  
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Platelets   Cell fragments that form platelet plugs and release chems for blood clotting  
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Plasma   liquid portion of the blood; contains water, proteins, waste products, nutrients  
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hematoiesis   the process that produces the formed elements of the blood; takes place in the red bone marrow  
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proethryoblasts   stem cells develop into RBC  
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myeloblasts   stem cells that develop into granulocytes  
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albumin   protein in plasma; viscocity, osmotic pressue  
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globulins   protein in plasma; transport lipids, carbs, etc  
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fibriongen   protein in plasma; blood clotting  
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lymphoblats   stem cells develop into lymphocytes  
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monoblasts   stem cells develop into monocytes  
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megakaryoblasts   stem cells develop into platelets  
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iron   required for oxygen transport  
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erythropotein   hormone stimulates RBC production; produced by kidneys in response to low blood O2 levels  
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chemotaxis   atraction and movement of WBC towards foreign materials or damaged cells; dead WBC + bacteria= pus  
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diapedesis   WBC cells become thin, elongate and move between or thru endothial cells of capillaries  
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monocytes   break down antigens and present them to lymphocytes for recognition  
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hemostasis   arrest of bleeding: vascular spasm, platelets plug, blood clotting  
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platelet plug formation   1. Von Willebrand factor causes adhesion of collagen and platelets2. ADP, thromboxones, etc cause cascade effectfribrogen forms bridge: platelet plug  
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coagulation   prothrombinase activate-> converted to thrombin-> fibronigen convert to fibrin. clot= fibrin+trapped blood cells, platelets and fluids  
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extrinsic clotting pathway   begins with chems outside blood; damaged tissues release tissue factor; when CA2 is present activates factor X, prothrombinase formed->thrombin->fibrogin to fibrin; thrombin activates factor XII to stabalize clot  
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intrinsic clotting pathway   begins with chems part of blood;  
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fibronylisis   clot retraction  
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blood grouping   determined by antigens on surface of RBCs  
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hemolytic disease of newborn   rh+ fetus, rh- mom; in second pregnancy antibodies caused by 1st pregnancy may attack fetal RBCs  
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