A&P2-ClassNotes P35 Immune Sys. #3/Test 3
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| LEUKOCYTE-INDUCING FACTORS are released by: | injured cells
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| LEUKOCYTE-INDUCING FACTORS help defense by: | Promoting rapid neutrophil release from red bone marrow
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| LEUKOCYTOSIS is a sign of: | inflammation
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| CHEMOTACTIC AGENTS are Inflammatory Chemicals that: | attract WBC's to area
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| MARGINATION (PAVEMENTING) is whenneutrophils: | cling to capillary walls as blood flow slows down
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| DIAPEDESIS (EMIGRATION) is: | neutrophils squeeze thru capillaries walls & into tissue spaces
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| What follows neutrophils into tissue spaces? | monocytes follow neutrophils within hours
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| Monocytes change from phagocytic slugs into: | MACROPHAGES-insatiable consumers
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| MACROPHAGES have lots of: | lysosomes in their cytoplasm
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| Macrophages replace neutrophils: | as primary agents at inflammation site
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| Macrophages are dominate at: | sites of chronic inflammation
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| PUS may form-it is: | dead/dying neutrophils, broken tissue cells & pathogens
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| INFECTIOUS GRANULOMAS are: | tumor-like growths of macrophages housing resistant bacteria
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| What may be covered by a fibrous capsule? | INFECTIOUS GRANULOMAS
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| 4 Types of transplants are: | Autografts, Isografts, Allografts, & Xenografts
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| Autografts are when: | self to self
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| Isografts are when: | genetically identical, ie: between twins
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| Allografts are when: | tissue is human to human
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| Xenografts is when: | tissue is between different species
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| AIDS is when HIV (human immunodeficiency virus): | causes destruction of defensive HELPER T-CELLS white blood cells
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| SCID is A/K/A | severe combined immunodeficiency disease
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| Hypersensitivities refers to: 4 | allergies, allergens, anaphylaxis and anaphylactic shock
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| Sarcoidosis (possibly autoimmune) | causes formation of granulomas in body organs; often assoc. w/lungs
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| Leukocytosis is: | increase in WBC's
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| During leukocytosis # of neutrophils: | in blood increase four to five fold within a few hours
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| Phagocytosis is what type of defense? | NON SPECIFIC BODY DEFENSE (NBD)
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| Phagocytes specialize in the: | engulfment of foreign pathogens on a grand scale
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| Phagocytes have large numbers of: | LYSOSOMES in the cytoplasm
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| RESPIRATORY BLAST is an alternative: | method of pathogen destruction
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| RESPIRATORY BLAST is a form of defense where chemicals from the immune system: | stimulate the phagocyte cells to release free radicals to destroy invaders
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