Lymphatic System
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what are the 3 important functions of the lymphatic system | show 🗑
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auto | show 🗑
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show | become, be produced
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show | moisture, fluid
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show | free, exempt
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inflamm- | show 🗑
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show | knot
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show | disease, sickness
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show | microscopic, closed-ended tubes
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The walls of lymphatic capillaries are formed from | show 🗑
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lymph | show 🗑
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The size of the lymphatic pathway small to large | show 🗑
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show | an endothelial lining, a middle layer of smooth muscle and elastic fibers, and an outer layer of connective tissue
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semilunar valves | show 🗑
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show | specialized organs
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show | drain lymph from the lymphatic vessels
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show | drains lymph from the lower limbs, lower abdominal wall, and pelvic organs
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show | drains the abdominal viscera
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show | drain lymph from portions of the thorax
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show | drains upper limbs
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show | portions of the neck and head
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show | thoracic and right lymphatic duct
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show | wider and longer of the two collecting ducts. It originates as an enlarged sac, the cisterna chyli
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show | intestinal, lumbar, and intercostal trunks, as well as from the left subclavian, left jugular, and left bronchomediastinal trunks.
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show | the left subclavian vein near its junction with the left jugular vein.
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right lymphatic duct originates in the | show 🗑
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show | right subclavian vein near its junction with the right jugular vein.
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right lymphatic drains lymph from | show 🗑
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show | it enters the venous system and becomes part of the plasma just before blood returns to the right atrium.
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Capillary blood pressure | show 🗑
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show | The osmotic effect of these plasma proteins which helps to draw fluid back into the blood capillaries by osmosis.
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lymph formation prevents the accumulation of excess tissue fluid, or edema by | show 🗑
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show | contracting skeletal muscles in the limbs, contraction of smooth muscle in the walls of the larger lymphatic trunks, and pressure changes from the action of skeletal muscles used in breathing.
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show | during exercise, due to the actions of skeletal muscles and pressure changes associated with breathing.
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show | venous
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show | The unencapsulated diffuse lymphatic tissue associated with the digestive, respiratory, urinary, and reproductive tracts
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show | are compact masses of lymphatic tissue included in the MALT
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show | the tonsils and appendix
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show | encapsulated lymphatic tissue :a capsule of connective tissue with many fibers encloses each organ.
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show | indented region of the lymph node where blood vessels and nerves join a lymph node
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show | enter separately at various points on its convex surface
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show | hilum
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show | compartments, functional units of the lymph node
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what are contained within lymphatic nodules | show 🗑
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where do B lymphocytes proliferate? | show 🗑
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the medulla contains mostly what kind of cells? | show 🗑
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show | Spaces in a lymph node that provide a complex network of chambers and channels through which lymph circulates
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The lymph nodes in the cervical region | show 🗑
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show | drain the upper limbs, the wall of the thorax, the mammary glands (breasts), and the upper wall of the abdomen.
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The lymph nodes in the supratrochlear region | show 🗑
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Lymph node of inguinal region | show 🗑
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show | receive lymph from the lymphatic vessels of the pelvic viscera, follow the iliac blood vessels.
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show | form chains along the main branches of the mesenteric arteries and the abdominal aorta and receive lymph from the abdominal viscera.
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show | in the mediastinum and along the trachea and bronchi. They receive lymph from the thoracic viscera and from the internal wall of the thorax.
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Thymus | show 🗑
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where is the thymus? | show 🗑
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largest lymphatic organ | show 🗑
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where is spleen located | show 🗑
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show | blood
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show | distributed throughout the spleen in tiny islands, is composed of splenic nodules, which are similar to the lymphatic nodules in lymph nodes and are packed with lymphocytes.
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Red pulp of spleen | show 🗑
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show | Blood/lymph
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what are the 3 cell types within lymphatic tissue | show 🗑
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where are lymph nodes generally located | show 🗑
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what structures lack lymph nodes? | show 🗑
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pathogens | show 🗑
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show | simple microorganisms such as bacteria, complex microorganisms such as protozoa, and spores of multicellular organisms such as fungi.
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Viruses are pathogens, but they are not considered organisms, because | show 🗑
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innate defense | show 🗑
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show | species resistance, mechanical barriers, inflammation, chemical barriers (enzyme action, interferon, and complement), natural killer cells, phagocytosis, and fever.
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show | these protective mechanisms are very precise, targeting specific pathogens
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adaptive defense mechanisms include | show 🗑
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show | quickly
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adaptive defense responds | show 🗑
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species resistance | show 🗑
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mechanical barriers | show 🗑
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pus | show 🗑
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exudates | show 🗑
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show | enzymes that kill pathogens and protect the body
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Interferons | show 🗑
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Defensins | show 🗑
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show | proteins that provide broad protection against bacteria, yeasts, some viruses,detect the sugar molecules or pattern in which they are clustered, binding much like velcro clings to fabric, thus making the pathogen more easily phagocytized.
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show | proteins (complement system), in plasma and other body fluids, that interact in an expanding series of reactions or cascade.
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show | rapid complement activation when a complement protein binds to an antibody attached to its specific antigen
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show | slower complement activation triggered by exposure to foreign antigens, in the absence of antibodies.
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show | small population of lymphocytes that are distinctly different from the lymphocytes that provide adaptive defense mechanisms, secrete perforins.
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perforins | show 🗑
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show | neutrophils and monocytes
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show | smaller particles
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show | larger particles
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show | IL-1 raises the thermoregulatory set point in the brain’s hypothalamus to maintain a higher body temperature. AKA endogenous pyrogen (“fire maker from within”)
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show | proteins, polysaccharides, glycoproteins, or glycolipids.
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show | large and complex, with few repeating parts.
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hapten | show 🗑
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show | 70/80 vs 20/30
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show | processed fragments of the antigen be attached to the surface of another type of cell, called an antigen-presenting cell
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cellular immune response | show 🗑
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show | polypeptides synthesized and secreted by T cells and some macrophages that enhance certain cellular responses to antigens
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what other substances do T cells secrete? | show 🗑
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helper T cell | show 🗑
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show | the type that HIV targets, is responsible for stimulating Bcells to aid immunity
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show | bind to the surfaces of antigen-bearing cells, where they release perforin protein that cuts porelike openings, destroying these cells, ontinually monitor the body’s cells, recognizing and eliminating tumor cells and cells infected with viruses.
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show | Cd8 cells produce memory T cells after contact with the antigen studded portion of a cell. This memory T cell than reacts to that pathogen in the future, destroying before the body starts to display symptoms (think antibodies)
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show | number of circulating antibodies in the bloodstream.
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