B2 Gene 12/1 Lec 7 Population Genetics
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| What is the Hardy-Weinberg Equilibrium | show 🗑
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| show | p + q = 1//q2=.16 thus q=.4//p +.4 = 1 thus p=.6//p2 + 2pq + q2 = 1//2pq-carriers thus 2(.6*.4)=.48//p2-homozygous dominant (normal hemoglobin allele) thus (.6*.6)=.36
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| show | the tendency to marry based on shared characteristics >> height, intelligence, ethnicity, etc
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| show | marrying of blood relatives
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| show | lethal traits, where allelic frequency should decrease// heterozygote advantage, where carriers may have increased fitness against certain pathogenic conditions, thus increasing allelic frequency
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| show | when all individuals of a population are descended from a relatively small number of ancestors, one of whom had a rare allele examples: polydactly among certain Amish groups or albinism among Hopi Indians
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| show | describes the case in which the heterozygote genotype has a higher relative fitness than either the homozygote dominant or homozygote recessive genotype. This favoring is one of the mechanisms that maintain polymorphism and explain genetic variability.
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| nonrandom mating _________ the incidence of selected alleles? | show 🗑
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| In the Hardy-Weinberg Equilibrium what does 2pq represent? | show 🗑
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| In the Hardy-Weinberg Equilibrium what does p2 (p squared) represent? | show 🗑
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| show | q2 = frequency of homozygous recessive individuals (aa)//p2 +2pq + q2 = 1
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| In the Hardy-Weinberg Equilibrium what does p represent? | show 🗑
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| show | q = frequency of recessive allele//p+q=1
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| show | When natural select, consanguinity, assortative mating/non-random mating, and/or small population size is present
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| show | In small populations. This is because in small populations each allele is more susceptible to change.
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| What is an allele | show 🗑
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| Do some alleles have higher likelihood of de novo mutation? | show 🗑
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