Chapters 12-16
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Central Nervous System (CNS) | consist of the brain and spinal cord
integration and command center
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Peripheral Nervous System (PNS) | nerves to spinal and cranial
carries messages to and from the spinal cord and brain
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afferent PNS | sensory and brings to
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efferent | motor and brings out
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Functions of the Autonomic Nervous system | innervates and regulates cardiac muscle, smooth muscle and glands without conscious control
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Parasympathetic (PNS) | digest and rest
decrease in BP, HR, RR, and pupil dilation
increase in secretion
parasympathomimetic
sympatholytic
acetolcholine
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Sympathetic (PNS) | fight or flight
increase in BP, HR, RR and pupil dilation
decrease in secretions
sympathomimetic
parasympatholytic
epi or nore
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function of neurons | basic structural unit of the nervous system
excitable cells that INITIATE and TRANSMIT electrical signals
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What is a Synapse? | the specific location where a neuron is functionally connected either to another neuron or an effector
2 types are chemical and electrical
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Chemical Synapse | between 2 neurons presynaptic neuron and postsynaptic neuron
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electrical synapse | composed of presynaptic and postsynaptic neuron physically bound together
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neurotransmitter | chemical released from a neuron that delivers info to another cell
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What is the most common neuron in the system? | multipolar neurons (brain/spinal cord) and in the autonomic ganglia (motor neurons)
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Define association neurons | more numerous than motor neurons
main function in spinal cord is that of inhibitory control
also interconnect other cells with one another
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Glial cells and functions | also known as neuroglia
found in CNS and PNS
smaller than neurons and capable of mitosis
DO NOT transmit electrical signals
assist neurons with their functions, physically protect and help nourish neurons
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What are graded potentials? | relatively small, short lived changes in the resting membrane potential caused by movement of small amounts of ions across the plasma membrane
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What is hyperpolarization? | change in the membrane potential to a value more negative than the resting potential
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Action potential is in relationship to what? | depolarization and repolarization
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Depolarization | gain of positive charge within a neuron
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repolarization | return of polarity from positive back to negative
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What does the integrated function of the NS imply? | process of combining info from many sources
neurons (nerve cells) have a part
dendrites designed to combine or integrate info and then get connections called synapses
sensory input-integration-motor output
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What is the function of the synaptic cleft? | extremely narrow fluid filled gap that helps decode the message and translates into a chemical message that then diffuses across the cleft to the postsynaptic cell
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What are ganglion (ganglia)? | structure containing a number of nerve cell bodies, typically linked by synapses and forming a swelling on the nerve fiber
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Function of Acetylcholinesterase | terminates synaptic transmission at the cholingeric synapses by hydrolyzing the neurotransmitter acetylcholine
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What is salutatory conduction? | occurs in myelinated axons action potential from one node of Ranvier to the next node
increase conduction velocity
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Chemical classes of neurotransmitters | amino acids
gastronsmitters
monoamines
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Amino acids | glutamate
aspartate
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gastronsmitters | nitric oxide
carbon monoxide
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monoamines | dopamine
norepinephrine
epinephrine
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Schwan cells | made up of white sheath
myelinate the axons of the PNS
supports the PNS
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What are nerve cell adhesion molecules (N-CAMS) | glycoprotein of immunoglobulin which binds to variety of other cell adhesion proteins to mediate adhesion, guidance, and differentiate during neural growth
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What is a generator potential? | stationary depolarization of a receptor that occurs in response to a stimulus and is graded according to its intensity
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What cranial nerves originate from the pons? | trigeminal nerve
abducens
facial nerve
vestibulocochlear nuclei
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What does the premotor cortex control? | also known as the somatic motor located within the frontal lobe
primarily responsible for coordinating learned, skilled motor activities-moving eyes
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What is the arbor vitae | internal region of white matter
distribution pattern resembles branches of a tree
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What parts consist of the brainstem? | Midbrain
pons
medulla oblongata
connects the cerebrum, diencephalon, and the cerebellum to the spinal cord
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Midbrain | superior
function in motor movement, eye and auditory, and visual processing
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Pons | sensory and motor tracts
located within and extends to connect the brain and spinal cord
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medulla oblongata | most caudal part of the brainstem
communication between the brain and spinal cord
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Where is cerebral spinal fluid found? | clear colorless liquid that circulates within the ventricles and subarachnoid space
exposed surfaces of the CNS and completely surrounds it
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Functions of cerebral spinal fluid | Buoyancy-ability to float in water, air or other liquid
protection
environmental stability
insulation
high concentration of glucose
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Function and location of the hypothalamus | anteroinferior region of the diencephalon
-master control of ANS and endocrine
-regulation of body temp
-control of emotional behavior
-control of food and water intake
-regulation of sleep-wake rhythms
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What is REM sleep associated with? | Rapid eye movement distinguished by their EEG patterns and presence of rapid eye movement
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What is coma? | a deep and profound state of unconsciousness from which the person can't be aroused, even by repeated painful stimuli
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Define Parkinson's Disease and associated symptoms | slow progressing neurologic condition that affects muscle movement and balance
deficiency of the neurotransmitter dopamine
-stiff posture
-expressionless face
-slow voluntary movements
-resting tremors (hands)
-shuffling gait
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What are the structures associated with the midbrain? | cerebral peduncles
superior cerebellar peduncles
medial lemniscus
substantia nigra
optic tract
superior/inferior colliculi
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cerebral peduncles | motor tracts anterolateral surfaces of midbrain
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superior cerebella peduncles | connecting cerebellum to the midbrain
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medial lemniscus | extends through the midbrain
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substantia nigra | bilaterally symmetrical nuclei with the midbrain
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What structures are associated with memory? | the limbic system
hippocampus and parahippocampal gyrus
amygdaloid body-help store and code memories
cingulate gyrus
olfactory bulbs, olfactory tracts, olfactory cortex
fornix
anterior thalamic nuclei
habenular nuclei, septal nuclei
mammillary bod
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What is broca's area? | known as motor speech area located in most individuals within the inferolateral portion of the left frontal lobe
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What separates the frontal lobe from the temporal lobe? | Lateral sulcus-deep groove
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What is procedural memory? | implicit
part of the long term memory responsible for knowing how to do things (motor skills)
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What is declarative memory? | explicit
memory of facts and events and refers to those memories that can be consciously recalled
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textbook definition of sleep | natural, temporary absence of consciousness from which a person can be aroused by normal stimulation
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What is epilepsy? | condition a person experiences repeated seizures over time
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Injury to the hypothalamus will result in ? | can cause a number of deficiencies to the ANS, endocrine, body temp, emotional behavior, anorexia, bulimia, and sleep wake rhythms
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What is the mildest consequence of traumatic brain injury (TBI) | concussion is the most common TBI that is temporary, abrupt loss of consciousness after a blow to the head or sudden stop of a moving head
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What is vestibular nuclei associated with? | cranial nuclei for vestibular nerve grouped in both the pons and the medulla in the brainstem
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Where are the 2nd order neurons located? | Dorsal horn/medullary nuclei
which transmit impulses to the thalamus and cerebellum
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Function of the anterolateral pathway | also known as SPINOTHALAMIC PATHWAY
located in anterior/lateral white funiculi of the spinal cord
relay sensory input related to crude touch and pressure as well as pain and temp
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Group C fibers capable of salutatory conduction? | unmyleinated, detect info involving pain and touch, can't ascend to cerebral cortex
Are NOT capable of salutatory conduction
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What is reticular formation in the brain? | Loosely organized mass of gray matter
extends slightly into the diencephalon and the spinal cord
functional brain system has both motor and sensory components
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What are the names of the convolutions of the brain - cerebrum? | gyri/raised ridges
sulci/grooves
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Brain waves and the types, What do they represent? | EEG-electroencephalogram is used to test brain waves
alpha- awake and resting
beta-awake with mental activity
theta-sleeping
delta-deep sleep
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What does brain wave amplitude indicate? | standard deviations indicative of how much alpha activity is occurring
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examples of serial processing | one at a time, step by step
mental tasks carried out in sequence
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Spastic paralysis suggest involvement of what type of neurons? | damage to upper motor neurons of primary motor cortex muscles can contract but can't relax
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When you link new facts to old material in the brain, what process? | association
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What are electrolyte concentrations Charges and what do they do intercellularly and extracellulary |
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What would cause a bidirectional production of an impulse? | when a nerve depolarizes
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If posterior portion of a neural tube failed to develop properly, What type of result would you expect? | spinal cord may be affected
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You have a pt who accidentally had a transection between T1 and L1 under normal circumstances what would be the result of such injury? |
paraplegia/ paralysis of legs and lower body
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