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Classic findings for USMLE review

Quiz yourself by thinking what should be in each of the black spaces below before clicking on it to display the answer.
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Disease/Finding
Association
show Often precedes squamous cell carcinoma  
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Addison's Disease   show
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Albright's syndrome   show
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show Guillain-Barré (↑ protein in CSF with only modest ↑ in cell count)  
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show Hereditary nephritis with nerve deafness  
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show Goodpasture's syndrome  
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show Scleroderma (CREST)  
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Anti-double-stranded DNA antibodies (ANA antibodies)   show
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show Pemphigus vulgaris  
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Antigliadin antibodies   show
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show Drug induced SLE  
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Anti-IgG antibodies   show
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show 1° biliary cirrhosis  
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Antineutrophil antibodies   show
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show Idiopathic thrombocytopenic purpura  
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show Marfan's syndrome  
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Argyll Robertson pupil   show
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Arnold-Chiari malformation   show
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show Rheumatic fever  
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show Wernicke's encephalopathy  
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show Acute myelogenous leukemia (especially the promyelocytic type)  
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Autosplenectomy   show
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Babinski's sign   show
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Baker's cyst in popliteal fossa   show
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show Ankylosing spondylitis  
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Bartter's syndrome   show
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Basophilic stippling of RBCs   show
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show Defective dystrophin; less severe than Duchenne's  
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Bell's palsy   show
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show Mulitple myeloma (kappa or lambda kight chains in urine), Waldenstrom's macroglobulinemia (IgM)  
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Berger's disease   show
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show Defect in platelet adhesion  
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show Sarcoidosis  
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Birbeck granules on EM   show
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Bloody tap on LP   show
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show Chronic bronchitis  
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Blue-domed cysts   show
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Blue sclera   show
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Boot-shaped heart on x-ray   show
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Bouchard's nodes   show
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Boutonniere's deformity   show
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show Actinomyces israelii  
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show Hemorrhage causes brown color of osteolytic cysts: 1. Hyperparathyroidism 2. Osteitis fibrosa cystica (von Recklinghausen's disease)  
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Brushfield's spots   show
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show X-linked agammaglobulinemia  
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Budd-Chiari syndrome   show
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show Small/medium-artery vasculitis  
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show 8:14 translocation; associated with EBV  
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show Lead poisoning  
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show Wegener's granulomatosis, polyarteritis nodosa  
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Café-au-lait spots   show
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Caisson disease   show
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show Duchenne's muscular dystrophy  
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show Granulosa-theca cell tumor of the ovary  
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show Chagas' disease  
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Cerebriform nuclei   show
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show Trypanosome infection  
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show 1° syphilis (not painful)  
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Chancroid   show
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show Multiple sclerosis (nystagmus, intention tremor, scanning speech); cholangitis (jaundice, RUQ pain, fever)  
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Charcot-Leyden crystals   show
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Chédiak-Higashi disease   show
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Cherry-red spot on macula   show
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Cheyne-Stokes respirations   show
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"Chocolate cysts"   show
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Chronic atrophic gastritis   show
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show Hypocalcemia (fascial muscle spasm upon tapping)  
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Clear cell adenocarcinoma of the vagina   show
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show Gardnerella vaginitis  
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show Osteosarcoma  
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show Mycoplasma pneumoniae, infectious mononucleosis  
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show Hypothyroidism  
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show Secondary syphilis  
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show Patent ductus arteriosus  
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Cori's disease   show
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show Chronic hypertension  
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Cough, conjunctivitis, coryza + fever   show
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show Toxic or viral hepatitis  
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show Herpesvirus  
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Crescents in Bowman's capsule   show
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show Congenital unconjugated hyperbilirubinemia  
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show Acute gastric ulcer associated with severe burns  
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show Klebsiella  
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Curschmann's spirals   show
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Cushing's ulcer   show
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show DIC  
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Depigmentation of neurons in substantia nigra   show
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Dermatitis, dementia, diarrhea   show
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Diabetes insipidus + exophthalmos + lesions of skull   show
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show Pasteurella multocida  
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Donovan bodies   show
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Dressler's syndrome   show
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Dubin-Johnson syndrome   show
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Duchenne's muscular dystrophy   show
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show Osteoarthritis (polished, ivory-like appearance of bones)  
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show Trisomy 18 associated with rocker-bottom feet, low-set ears, heart disease  
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show Late cyanosis shunt (uncorrected L --> R shunt becomes R --> L shunt)  
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show Ehlers-Danlos syndrome  
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show Superior trunk brachial plexus injury ("waiter's tip")  
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Erythema chronicum migrans   show
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Fanconi's syndrome   show
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show Acute cholecystitis  
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show Alcoholism  
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Ferruginous bodies   show
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Gardner's syndrome   show
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Gaucher's disease   show
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show 1° TB  
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show Benign congenital unconjugated hyperbilirubinemia  
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show Defect in platelet aggregation  
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show Autoantibodies against alveolar and glomerular basement membrane proteins  
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Gowers' maneuver   show
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show Idiopathic polyneuritis  
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show β-thalassemia, sickle cell anemia (extramedullary hematopoiesis)  
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Hand-Schuller-Christian disease   show
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show Sickle cell anemia  
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show Choriocarcinoma, hydatiform mole (occurs with and without embryo)  
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show Osteoarthritis (DIP swelling 2° to osteoarthritis)  
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show G6PD deficiency  
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Henoch-Schonlein purpura   show
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Heterophil antibodies   show
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HbF   show
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show Wet beriberi (thiamine, vitamin B₁ deficiency)  
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show Reiter's syndrome, ankylosing spondylitis  
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HLA-DR3 or -DR4   show
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show Neuroblastoma  
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Honeycomb lung on x-ray   show
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Horner's syndrome   show
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Howell-Jolly bodies   show
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show Caudate degeneration (autosomal dominant)  
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Hyperphagia + hypersexuality + hyperorality + hyperdocility   show
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Hyperpigmentation of the skin   show
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show Macrocytic anemia  
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show Conn's syndrome  
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show Iron deficiency anemia, lead poisoning  
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show Anencephaly, spina bifida (neural tube defects)  
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Increased uric acid levels   show
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show Adenovirus (causes hyperplasia of Peyer's pathches)  
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Janeway lesions   show
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show Syphilis - overaggressive treatment of asymptomatic pt that causes symptoms due to rapid lysis  
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Job's syndrome   show
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show AIDS in MSM (men who have sex with men)  
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Kartagener's syndrome   show
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show Wilson's disease  
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show Squamous cell carcinoma  
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show Diabetic neuropathy  
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show Bilateral amygdala lesions  
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show HPV  
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Koplik spots   show
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Krukenberg tumor   show
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show Diabetic ketoacidosis (DKA)  
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show Marfan's syndrome (fibrillin deficit)  
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Lesch-Nyhan syndrome   show
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Lewy bodies   show
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Libman-Sacks disease   show
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show Aterial thrombus  
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Lisch nodules   show
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Low serum ceruloplasmin   show
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show Epidural hematoma  
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"Lumpy-bumpy" appearance of glomeruli on immunofluorescence   show
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show Multiple myeloma  
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Mallory bodies   show
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Mallory-Weiss syndrome   show
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show Muscle phosphorylase deficiency  
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McBurney's sign   show
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show Multiple sclerosis  
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Monoclonal antibody spike   show
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show Hypothyroidism  
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show Wegener's and Goodpasture's (hemoptysis and glomerular disease)  
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Needle-shaped, negatively birefringent crystals   show
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show Rabies  
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Nephritis + cataracts + hearing loss   show
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show Alzheimer's disease  
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show Sphingomyelinase deficiency  
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No lacation postpartum   show
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Nutmeg liver   show
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show Malignant mesothelioma  
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"Orphan Annie" nuclei   show
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show Endocarditis  
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show CMV  
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Painless jaundice   show
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show Henoch-Schönlein purpura  
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show Bronchogenic apical tumor associated with Horner's syndrome  
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Pannus   show
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Parkinson's disease   show
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Periosteal elevation on x-ray   show
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Peutz-Jeghers syndrome   show
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show Penile fibrosis  
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show CML (may sometime be associated with AML)  
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Pick bodies   show
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show Progressive dementia, similar to Alzheimer's  
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show Emphysema (centroacinar [smoking], panacinar [α₁-antitrypsin defiency])  
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show Esophageal webs with iron deficiency anemia  
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Podagra   show
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Podocyte fusion   show
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Polyneuropathy, cardiac pathology, and edema   show
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show Guillain-Barré syndrome  
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Pompe's disease   show
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Port-wine stain   show
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Positive anterior "drawer sign"   show
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Pott's disease   show
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show Glioblastoma multiforme  
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show Ewing's sarcoma  
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Ptosis, miosis, anhidrosis   show
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Rash on palms and soles   show
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show Acute glomerulonephritis  
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Recurrent pulmonary Pseudomonas and S. aureus infections   show
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show Paroxysmal nocturnal hemoglobinuria  
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show Hodgkin's lymphoma  
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Increased Reid index   show
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Reinke crystals   show
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Reiter's syndrome   show
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Renal cell carcinoma + cavernous hemangiomas + adenomas   show
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show Acute toxic/viral nephrosis  
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show Pseudogout  
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Rib notching   show
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show Endocarditis  
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Rotor's syndrome   show
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Rouleaux formation (RBCs)   show
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show Multiple myeloma  
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S3   show
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show Aortic stenosis, hypertrophic subaortic stenosis  
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show Yolk sac tumor  
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Senile plaques   show
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Sézary syndrome   show
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show Postpartum pituitary necrosis  
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show Neisseria meningitidis  
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show Gastric carcinoma  
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show Down syndrome  
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show MEN type IIa  
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Sjögren's syndrome   show
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Skip lesions   show
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"Slapped cheek"   show
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Smith antigen   show
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"Smudge cell"   show
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Soap bubble on x-ray   show
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show Membranous glomerulonephritis  
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Spitz nevus   show
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show Endocarditis  
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show Burkitt's lymphoma  
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show Scarlet fever  
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show Turner's syndrome  
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String sign on x-ray   show
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show Postreptoccocal glomerulonephritis  
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Suboccipital lymphadenopathy   show
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show Actinomyces israelii  
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Swollen gums, bruising, poor wound healing, anemia   show
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show Aortic valve stenosis  
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show Burkitt's lymphoma (c-myc activation)  
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t(9;22)   show
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show 3° syphilis  
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show Familial hypercholesterolemia  
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Thumb sign on lateral x-ray   show
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Thyroidization of kidney   show
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Tophi   show
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show Membranoproliferative glomerulonephritis  
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Trousseau's sign   show
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show Left supraclavicular node enlargement from metastatic carcinoma of the stomach  
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Virchow's triad   show
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von Recklinghausen's disease   show
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von Recklinghausen's disease of the bone   show
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Wallenberg's syndrome   show
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Waterhouse-Friderichsen syndrome   show
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show Chronic end-stage renal disease  
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show Acute pyelonephritis  
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show Acute cystitis  
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Wermer's syndrome   show
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show Malabsorption syndrome caused by Tropheryma whippelii  
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Wilson's disease   show
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"Wire loop" appearance on LM   show
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Xanthochromia (CSF)   show
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Xerostomia + arthritis + keratoconjunctivitis sicca   show
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show Upper GI diverticulum  
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Zollinger-Ellison syndrome   show
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