Classic findings for USMLE review
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show | Often precedes squamous cell carcinoma
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Addison's Disease | show 🗑
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Albright's syndrome | show 🗑
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show | Guillain-Barré (↑ protein in CSF with only modest ↑ in cell count)
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show | Hereditary nephritis with nerve deafness
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show | Goodpasture's syndrome
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show | Scleroderma (CREST)
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Anti-double-stranded DNA antibodies (ANA antibodies) | show 🗑
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show | Pemphigus vulgaris
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Antigliadin antibodies | show 🗑
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show | Drug induced SLE
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Anti-IgG antibodies | show 🗑
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show | 1° biliary cirrhosis
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Antineutrophil antibodies | show 🗑
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show | Idiopathic thrombocytopenic purpura
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show | Marfan's syndrome
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Argyll Robertson pupil | show 🗑
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Arnold-Chiari malformation | show 🗑
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show | Rheumatic fever
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show | Wernicke's encephalopathy
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show | Acute myelogenous leukemia (especially the promyelocytic type)
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Autosplenectomy | show 🗑
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Babinski's sign | show 🗑
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Baker's cyst in popliteal fossa | show 🗑
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show | Ankylosing spondylitis
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Bartter's syndrome | show 🗑
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Basophilic stippling of RBCs | show 🗑
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show | Defective dystrophin; less severe than Duchenne's
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Bell's palsy | show 🗑
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show | Mulitple myeloma (kappa or lambda kight chains in urine), Waldenstrom's macroglobulinemia (IgM)
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Berger's disease | show 🗑
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show | Defect in platelet adhesion
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show | Sarcoidosis
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Birbeck granules on EM | show 🗑
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Bloody tap on LP | show 🗑
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show | Chronic bronchitis
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Blue-domed cysts | show 🗑
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Blue sclera | show 🗑
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Boot-shaped heart on x-ray | show 🗑
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Bouchard's nodes | show 🗑
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Boutonniere's deformity | show 🗑
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show | Actinomyces israelii
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show | Hemorrhage causes brown color of osteolytic cysts:
1. Hyperparathyroidism
2. Osteitis fibrosa cystica (von Recklinghausen's disease)
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Brushfield's spots | show 🗑
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show | X-linked agammaglobulinemia
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Budd-Chiari syndrome | show 🗑
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show | Small/medium-artery vasculitis
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show | 8:14 translocation; associated with EBV
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show | Lead poisoning
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show | Wegener's granulomatosis, polyarteritis nodosa
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Café-au-lait spots | show 🗑
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Caisson disease | show 🗑
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show | Duchenne's muscular dystrophy
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show | Granulosa-theca cell tumor of the ovary
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show | Chagas' disease
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Cerebriform nuclei | show 🗑
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show | Trypanosome infection
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show | 1° syphilis (not painful)
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Chancroid | show 🗑
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show | Multiple sclerosis (nystagmus, intention tremor, scanning speech); cholangitis (jaundice, RUQ pain, fever)
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Charcot-Leyden crystals | show 🗑
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Chédiak-Higashi disease | show 🗑
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Cherry-red spot on macula | show 🗑
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Cheyne-Stokes respirations | show 🗑
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"Chocolate cysts" | show 🗑
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Chronic atrophic gastritis | show 🗑
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show | Hypocalcemia (fascial muscle spasm upon tapping)
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Clear cell adenocarcinoma of the vagina | show 🗑
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show | Gardnerella vaginitis
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show | Osteosarcoma
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show | Mycoplasma pneumoniae, infectious mononucleosis
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show | Hypothyroidism
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show | Secondary syphilis
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show | Patent ductus arteriosus
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Cori's disease | show 🗑
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show | Chronic hypertension
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Cough, conjunctivitis, coryza + fever | show 🗑
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show | Toxic or viral hepatitis
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show | Herpesvirus
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Crescents in Bowman's capsule | show 🗑
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show | Congenital unconjugated hyperbilirubinemia
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show | Acute gastric ulcer associated with severe burns
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show | Klebsiella
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Curschmann's spirals | show 🗑
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Cushing's ulcer | show 🗑
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show | DIC
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Depigmentation of neurons in substantia nigra | show 🗑
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Dermatitis, dementia, diarrhea | show 🗑
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Diabetes insipidus + exophthalmos + lesions of skull | show 🗑
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show | Pasteurella multocida
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Donovan bodies | show 🗑
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Dressler's syndrome | show 🗑
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Dubin-Johnson syndrome | show 🗑
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Duchenne's muscular dystrophy | show 🗑
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show | Osteoarthritis (polished, ivory-like appearance of bones)
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show | Trisomy 18 associated with rocker-bottom feet, low-set ears, heart disease
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show | Late cyanosis shunt (uncorrected L --> R shunt becomes R --> L shunt)
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show | Ehlers-Danlos syndrome
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show | Superior trunk brachial plexus injury ("waiter's tip")
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Erythema chronicum migrans | show 🗑
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Fanconi's syndrome | show 🗑
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show | Acute cholecystitis
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show | Alcoholism
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Ferruginous bodies | show 🗑
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Gardner's syndrome | show 🗑
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Gaucher's disease | show 🗑
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show | 1° TB
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show | Benign congenital unconjugated hyperbilirubinemia
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show | Defect in platelet aggregation
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show | Autoantibodies against alveolar and glomerular basement membrane proteins
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Gowers' maneuver | show 🗑
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show | Idiopathic polyneuritis
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show | β-thalassemia, sickle cell anemia (extramedullary hematopoiesis)
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Hand-Schuller-Christian disease | show 🗑
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show | Sickle cell anemia
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show | Choriocarcinoma, hydatiform mole (occurs with and without embryo)
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show | Osteoarthritis (DIP swelling 2° to osteoarthritis)
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show | G6PD deficiency
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Henoch-Schonlein purpura | show 🗑
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Heterophil antibodies | show 🗑
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HbF | show 🗑
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show | Wet beriberi (thiamine, vitamin B₁ deficiency)
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show | Reiter's syndrome, ankylosing spondylitis
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HLA-DR3 or -DR4 | show 🗑
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show | Neuroblastoma
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Honeycomb lung on x-ray | show 🗑
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Horner's syndrome | show 🗑
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Howell-Jolly bodies | show 🗑
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show | Caudate degeneration (autosomal dominant)
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Hyperphagia + hypersexuality + hyperorality + hyperdocility | show 🗑
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Hyperpigmentation of the skin | show 🗑
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show | Macrocytic anemia
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show | Conn's syndrome
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show | Iron deficiency anemia, lead poisoning
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show | Anencephaly, spina bifida (neural tube defects)
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Increased uric acid levels | show 🗑
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show | Adenovirus (causes hyperplasia of Peyer's pathches)
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Janeway lesions | show 🗑
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show | Syphilis - overaggressive treatment of asymptomatic pt that causes symptoms due to rapid lysis
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Job's syndrome | show 🗑
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show | AIDS in MSM (men who have sex with men)
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Kartagener's syndrome | show 🗑
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show | Wilson's disease
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show | Squamous cell carcinoma
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show | Diabetic neuropathy
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show | Bilateral amygdala lesions
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show | HPV
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Koplik spots | show 🗑
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Krukenberg tumor | show 🗑
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show | Diabetic ketoacidosis (DKA)
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show | Marfan's syndrome (fibrillin deficit)
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Lesch-Nyhan syndrome | show 🗑
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Lewy bodies | show 🗑
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Libman-Sacks disease | show 🗑
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show | Aterial thrombus
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Lisch nodules | show 🗑
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Low serum ceruloplasmin | show 🗑
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show | Epidural hematoma
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"Lumpy-bumpy" appearance of glomeruli on immunofluorescence | show 🗑
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show | Multiple myeloma
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Mallory bodies | show 🗑
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Mallory-Weiss syndrome | show 🗑
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show | Muscle phosphorylase deficiency
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McBurney's sign | show 🗑
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show | Multiple sclerosis
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Monoclonal antibody spike | show 🗑
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show | Hypothyroidism
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show | Wegener's and Goodpasture's (hemoptysis and glomerular disease)
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Needle-shaped, negatively birefringent crystals | show 🗑
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show | Rabies
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Nephritis + cataracts + hearing loss | show 🗑
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show | Alzheimer's disease
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show | Sphingomyelinase deficiency
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No lacation postpartum | show 🗑
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Nutmeg liver | show 🗑
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show | Malignant mesothelioma
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"Orphan Annie" nuclei | show 🗑
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show | Endocarditis
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show | CMV
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Painless jaundice | show 🗑
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show | Henoch-Schönlein purpura
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show | Bronchogenic apical tumor associated with Horner's syndrome
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Pannus | show 🗑
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Parkinson's disease | show 🗑
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Periosteal elevation on x-ray | show 🗑
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Peutz-Jeghers syndrome | show 🗑
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show | Penile fibrosis
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show | CML (may sometime be associated with AML)
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Pick bodies | show 🗑
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show | Progressive dementia, similar to Alzheimer's
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show | Emphysema (centroacinar [smoking], panacinar [α₁-antitrypsin defiency])
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show | Esophageal webs with iron deficiency anemia
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Podagra | show 🗑
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Podocyte fusion | show 🗑
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Polyneuropathy, cardiac pathology, and edema | show 🗑
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show | Guillain-Barré syndrome
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Pompe's disease | show 🗑
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Port-wine stain | show 🗑
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Positive anterior "drawer sign" | show 🗑
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Pott's disease | show 🗑
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show | Glioblastoma multiforme
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show | Ewing's sarcoma
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Ptosis, miosis, anhidrosis | show 🗑
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Rash on palms and soles | show 🗑
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show | Acute glomerulonephritis
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Recurrent pulmonary Pseudomonas and S. aureus infections | show 🗑
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show | Paroxysmal nocturnal hemoglobinuria
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show | Hodgkin's lymphoma
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Increased Reid index | show 🗑
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Reinke crystals | show 🗑
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Reiter's syndrome | show 🗑
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Renal cell carcinoma + cavernous hemangiomas + adenomas | show 🗑
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show | Acute toxic/viral nephrosis
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show | Pseudogout
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Rib notching | show 🗑
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show | Endocarditis
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Rotor's syndrome | show 🗑
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Rouleaux formation (RBCs) | show 🗑
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show | Multiple myeloma
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S3 | show 🗑
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show | Aortic stenosis, hypertrophic subaortic stenosis
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show | Yolk sac tumor
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Senile plaques | show 🗑
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Sézary syndrome | show 🗑
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show | Postpartum pituitary necrosis
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show | Neisseria meningitidis
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show | Gastric carcinoma
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show | Down syndrome
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show | MEN type IIa
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Sjögren's syndrome | show 🗑
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Skip lesions | show 🗑
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"Slapped cheek" | show 🗑
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Smith antigen | show 🗑
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"Smudge cell" | show 🗑
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Soap bubble on x-ray | show 🗑
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show | Membranous glomerulonephritis
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Spitz nevus | show 🗑
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show | Endocarditis
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show | Burkitt's lymphoma
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show | Scarlet fever
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show | Turner's syndrome
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String sign on x-ray | show 🗑
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show | Postreptoccocal glomerulonephritis
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Suboccipital lymphadenopathy | show 🗑
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show | Actinomyces israelii
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Swollen gums, bruising, poor wound healing, anemia | show 🗑
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show | Aortic valve stenosis
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show | Burkitt's lymphoma (c-myc activation)
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t(9;22) | show 🗑
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show | 3° syphilis
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show | Familial hypercholesterolemia
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Thumb sign on lateral x-ray | show 🗑
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Thyroidization of kidney | show 🗑
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Tophi | show 🗑
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show | Membranoproliferative glomerulonephritis
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Trousseau's sign | show 🗑
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show | Left supraclavicular node enlargement from metastatic carcinoma of the stomach
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Virchow's triad | show 🗑
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von Recklinghausen's disease | show 🗑
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von Recklinghausen's disease of the bone | show 🗑
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Wallenberg's syndrome | show 🗑
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Waterhouse-Friderichsen syndrome | show 🗑
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show | Chronic end-stage renal disease
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show | Acute pyelonephritis
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show | Acute cystitis
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Wermer's syndrome | show 🗑
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show | Malabsorption syndrome caused by Tropheryma whippelii
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Wilson's disease | show 🗑
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"Wire loop" appearance on LM | show 🗑
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Xanthochromia (CSF) | show 🗑
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Xerostomia + arthritis + keratoconjunctivitis sicca | show 🗑
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show | Upper GI diverticulum
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Zollinger-Ellison syndrome | show 🗑
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