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A & P Chapter 10

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Term
Definition
Hematocrit   Percentage of total blood volume that is composed of red blood cells.  
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Hemoglobin   Essential molecule of the red blood cell that serves as the binding site for oxygen and carbon dioxide; composed of two molecules: globin and heme.  
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Hemolysis   Rupture of red blood cells as a result of disease or old age.  
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Hemostasis   Sequence of events that cause a blood clot to form and bleeding to stop.  
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Plasma   Liquid component of blood.  
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Platelets   Part of the formed elements of the blood; play a vital role in blood clotting.  
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Red Blood Cells   Contain hemoglobin, a protein responsible for oxygen and carbon dioxide exchange; erythoctes.  
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White Blood Cells   Fight Infection and protect the body through various mechanisms; leukocytes.  
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Agglutination   Red blood cells clumping together usually in response to an antibody; can block small blood vessels and cause hemolysis.  
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Antibody   Cells that circulate in plasma and attack red blood cells with foreign antigens or antigens that are different from those of the host.  
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Antigen   Protein on the surface of RBCs that is used to identify blood type; a molecule on the surface of cells that identifies cells as either "self" or "nonself" cells.  
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Erythoblastosis   A severe hemolytic disease of a fetus or newborn caused by the production of maternal antibodies against the fetal red blood cell antigens, usually involving RH incompatibility between the mother and fetus.  
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Rh Factor   Antigen of the Rh blood group that is found on the surface of red blood cells; people with the Rh factor are Rh positive and those lacking it are Rh negative.  
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RhoGAM   Immune serum that prevents a mother's blood from becoming sensitized to foreign antibodies from her fetus.  
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Universal Donor   Someone with type O blood, type O has no antigens that an be attacked by the host's blood, so it can be donated to anyone.  
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Universal Recipient   Someone with type AB blood; type AB blood has neither A or B antibodies, so a universal recipient can safely receive a transfusion of any blood type.  
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ALL   Most common form of leukemia in adults over 70, overproduction of lymphocytes.  
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AML   Most common form of leukemia in adults, develops when the bone marrow produces too many myeloblasts,  
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Anemia   A condition characterized by a decrease in the number of red blood cells or an insufficient amount of hemoglobin in the red blood cells.  
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CLL   Leukemia characterized by extremely high levels of lymphocytes; most often found in middle-age adults.  
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CML   Form of leukemia characterized by overproduction of granulocytes.  
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Hemophilia   Blood does not clot properly due to the absence of a clotting factor.  
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Iron-Deficient Anemia   Most common anemia; caused by an insufficient dietary intake of iron, loss of iron from intestinal bleeding, or iron-level depletion during pregnancy.  
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Jaundice   Blood disorder characterized by yellow-colored skin and whites of the eyes.  
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Leukemia   Cancer caused by the production of an extremely high number of immature white blood cells in the bone marrow.  
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Pernicious Anemia   Severe anemia caused by the inability of the intestines to absorb vitamin B12 which is essential for the formation of red blood cells, often occurs in older adults.  
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Phlebotomy   Drawing of blood; standard treatment for polycythemia.  
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Polycythemia   Condition in which the bone marrow manufactures too many red blood cells, caused by prolonged altitude exposure and a genetic mutation.  
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Sickle Cell Anemia   Disease in which the red blood cells are shaped like a sickle or crescent rather than a disk; caused by irregularly shaped hemoglobin molecules in the red blood cells,  
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