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Patho

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Question
Answer
Corrigan's Pulse:   Aortic Regurg. (AR, AI)  
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Pulsus Bisferiens:   HOCM, IHSS  
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Pulsus tarvus:   Aortic Stenosis (AS)  
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Pulsus Alternans:   CHF  
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Pulsus Bigeminus:   (High beat, Low beat, Pause)  
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Stenosis:   Leads to Pressure Overload, Chamber hypertrophies  
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Regurgitation:   Leads to Stretching & Volume Overload. (leaks)  
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Mitral Stenosis pathology is classified as?   Inflow Obstruction  
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What condition may be associated with LV inflow obstruction?   LA Myxoma (Tumors)  
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Valve "Doming" with distal chamber enlargement is associated with?   Valvular stenosis  
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Most right sided heart murmurs are accentuated (more pronouced) by?   Inspiration  
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A pansystolic heart murmur occurs between what heart sounds?   s1-s2  
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A grade 1 murmur:   Is barely audible (faint)  
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The most common arrhythmia associated with chronic mitral valve disease with CHF is?   Atrial Fibrillation  
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What type of infection may lead to rheumatic fever?   Alpha or hemolytic streptococcus (throat infection)  
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Rheumatic fever may be prevented by treating ____ infections with ____?   Bacterial throat/ Penicillin  
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What valve is most commonly damaged from Rheumatic Fever?   Mitral Valve  
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The predominate cause of Mitral Stenosis is?   Rheumatic Fever  
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Chronic Mitral Stenosis patients are prone to develop a "2nd stenosis" termed:   Reactive Pulmonary Hypertenion  
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Signs and Symptoms of Mitral stenosis may be easily confused with those of?   La myxoma orCor triatriatum  
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Primary sign or symptom with severe mitral regurg (MR):   SOB (Shortness of Breath)  
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Increasing the Cardiac Output in Mitral Stenosis will?   Increase the Diastolic pressure gradient  
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Things that could be done to more accuately evaluate MILD Mitral stenosis:   Speed the heart rate / Administer Chronotropic drugs to increase CO / Exercise him during Cath. {ANYTHING TO INCREASE CO}  
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What is the hemodynamic effect of Severe Mitral Stenosis?   Pulmonary Artery Hypertension  
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The Murmur of (MR) commonly radiates towards the?   Back  
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If a patient has Atrial Fib, what should be taken into account when reading a PAW preassure?   Atrial fib removes the "a" waves from the pressure tracing.  
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What auscultatory finding is most consistent with Mitral Valve incompetence:   Even intensity pansystolic murmur, best heard at the apex.  
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What (MR) cardiac output is higher than all the other measurements?   Increased LVMF (LV angio CO)  
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Acute (MR) is most often due to?   Chordal rupture / Papillary muscle rupture  
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Progression of MR in order:   Acute Uncompensated / Sub-acute MR Chronic Compensated / Chronic Decompensated  
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Which stage of MR has the largest "a" waves?   2nd stage (Sub-acute MR)  
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Which stage of MR has the largest "V" waves?   3rd stage (Chronic compensated MR)  
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Which type of angiogram would best define a failed mitral valve leaflet?   Left Ventriculogram / RAO view  
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Therapy for Mitral regurgitation includes:   Vasodilators (Nitrates, ACE inhib) Mechanical counterpulsation (IABP)  
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Which murmur is most consistent with Aortic stenosis?   DIamond-shaped ejection murmur, radiating towards the neck  
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In USA, most common form of (AS) in younger patients?   Congenital bicuspid AS  
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A patient with AS will likely have?   Large "a" waves  
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Brokenbrough's sign is associated with?   HOCM  
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Where is the Ligamentum arteriosum   Connective tissue just past the inomiate and subclavians,which attactches the aorta to the PA  
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Appropriate medical therapies for HOCM/IHSS   Beta Blockers / Calcium Channel Blockers  
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Austin Flint Murmur   common in Severe AS Mid diasystolic to presystolic  
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Progression of AS in order:   Normal LV / Severe acute AR Chronic compensated / Chronic decompensated AR  
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What stage of AR has the greatest EF and LV stroke volume?   3rd stage (Chronic Compensated AR)  
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What stage of AR has the highest LV-edp?   2nd stage (Severe acute AR)  
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Which of the four valve diseases complicates hemostatis, and increases the likelihood of femoral hematoma?   AR  
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Some AI (AR) and MVP (MR) patients suffer from an autosomal connective tissue syndrome called?   Marfan's Syndrome  
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Common signs associated with advanced pericardial tamponade:   Arterial Pulsus paradoxus / Prominest venous "X" descent wave Elevated venous pressures / Equalized diastolic preassure trac.  
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Common signs associated with advanced constrictive pericarditis:   Kusmaul's sign / Square root sign Elevated venous pressures / Equalized diastolic pressures  
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Electrocardiographic changes associated with pericarditis:   Lowered PR segment / Elevated S-T segment T-wave inversion  
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Cardiac rupture only occurs with?   Transmural Infarction  
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A false LV ventricular aneurysm is composed of bulging?   Pericardium and clotted hematoma  
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Which cardiac enzyme peaks early, Usually 6-7 hours after MI and declines rapidly?   Myoglobin  
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which cardiac enzyme peaks around, Usually 24 hours after MI?   CK-MB  
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Serum markers for cardiac damage?   Troponin (cTnl) / Lactic Dehydrogenase (G6P) Creatine Kinase (CK-MB)  
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Most common arrhythmia found in patients recovering from MI is?   PVC's (VPC's)  
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Warning symptoms of a heart attack:   Severe indigestion / Pressure in the center of chest Chest pain that moves to shoulders, neck, or arms.  
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Referred angina pain from MI is commonly located?   Along the ulnar aspect of the Left Arm  
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Angina pectoris is often described as?   "Band across chest" / "Squeezing or strangling sensation" "Pressure sensation like weight on chest"  
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Patient with angina, but arteries all appear normal, even during stress. This is called?   Syndrome X  
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Three major risk factors associated with heart attack include:   Cigarettes / High Blood cholesterol / Hypertension  
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ECG associated with Transmural MI is?   Pathologic Q wave  
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ECG associated with acute MI is?   ST segment elevation  
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Compensatory mechanisms used to maintain cardiac output in CHF:   Increase Preload / Myocardial hypertrophy / Increased catecholamines  
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Right side CHF eventually leads to?   RVH, RAD, and atrial hypertrophy  
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Activation of the "Renin-Angiotensin" system in low cardiac states;   Vasoconstriction / NA+ retention  
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Common cause of Isolated RHF is?   Emphysema  
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Common signs of RHF?   Swollen puffy legs / Enlarged liver / Distended neck veins  
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HOCM is a?   Genetic disorder with hypertrophied and hypercontractile LV  
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New York Heart classification:   I No undue symptoms with normal activites II Comfortable at rest, slight fatique III Comfortable at rest, symptoms with activity IV Symptoms at Rest  
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Rare form of heart failure, patient has good pressures:   High output HF  
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CHF patient must sit up to get his breath, this is called?   Orthopnea  
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Diuretics in the treatment of congestive heart failure are intended to?   Decrease preload  
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Medical treatment for acute CHF:   Diuretics / Vasodilators  
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Signs of Circulatory Shock:   Cold clammy skin / Collapsed neck veins / Decreased urine output / Hypotension  
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acutely dyspnic anaphylactic shock:   IV fluids / IV epinephrine  
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During Heart/Lung bypass surgery, patients are cooled to reduce metabolic rate. Termed: ____ an body temp is lowered too:____?   Moderate Hypothermia / 24-32 C  
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During CABG surgery, cold KCI cardioplegia solution is used, why?   Infused directly into the coronaries to quiet the heart so surgeons can work, Primary function is to induce Diastolic arrest (flaccid)  
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List the 5 components of a bypass circuit in order 1-8   Arterial Line and Cannula / Bubble trap and Filter / Arterial Roller pump / Oxygenator and heart Exchanger / Venous Reservoir / Sucker line, pump & filter / Venous Cannula and Return line / Vent Line  
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Arterial pressure of a pt. while on cardiopulmonary bypass?   Sine wave shape / BP around 50mmHg  
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Range of blood flow required for an average Normothermic persion? (perfusionists adjust the pump flow rate to CI of).   2.0-2.2 L/min/M2  
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Gold standard treatment for atherosclerotic stenosis of the common carotid bifurcation is?   Carotid endarterectomy  
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What type of Mitral Stenosis surgery is descriped? "Small incision is made in the LA and the surgeons finger pushes through the LA into the tight mitral valve, enlarging it.   Closed Mitral Commissurotomy  
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List 5 types of prosthetic heart valves:   Ball in cage / Disk in cage / Bi-leaflet / Tilting disk / Tissue valve  
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Ball in Cage valve:   Starr valve, longest record, disadv.. is bulky cage so no small hearts used, blood flows around ball.  
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Disk in Cage valve:   One disc pops open, blood flows around all sides, seldom used now  
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Bi-leaflet valve:   St.Jude mechanical valve, most commonly used,  
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Tilting Disk valve:   "toilet seat valve", one disc pivots, low profile and excellent hemodynamic charact.., MORE thrombogenic than Bi-leaflets  
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Tissue valve:   "porcine" or "pig" , least thrombogenic, least durable.  
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Ball in Cage valve inventor:   Starr-edwards, Smeloff, Braunwald  
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Disk in Cage valve inventor:   Hufnagel, Kay-shiley, Beall  
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Bi-leaflet valve inventor:   St judes, Duromedics  
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Tilting Disk valve inventor:   Lillehel, Bjork, Onmiscience  
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Tissue valve inventor:   Carpentier-edwards, Hancock  
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What type of prosthetic valve does NOT usually require anticoagulation?   Tissue valve by Carpentier-edwards, Hancock porcine.  
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What prosthetic valve should be used in the tricuspid position?   Tissue vavle by Carpentier-edwards, Hancock porcine (because tricuspid valve has lowest blood flow, making it more likely to thrombose. Therefore a tissue valve is what you want)  
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Valve from another human:   Homo-graft  
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Valve from the same individual:   Auto-graft  
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Valve from a different species:   Hetero-graft  
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Valve from metal and polycarbons:   Mechanical prosthesis  
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Younger patients with severe mitral valve regurgitation should be treated with?   Mitral Valve repair  
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Surgery for AR on young people, that replaces aortic valve with a pulmonary graft?   Ross procedure  
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A blood abnormality commonly found in pt. with prosthetic valves is?   Hemolytic anemia  
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Mechanical valve with the best flow, and commonly implanted worldwide?   Bileaflet, St jude  
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What type of bypass is the fastest for an emergency RCA bypass?   Saphenous veins  
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List 3 advantages of IMA grafts:   Less atherosclerosis / less intimal hyperplasia / closer in size match to coronaries  
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overall intra-operative mortallity rate for CABG surgeries:   5%  
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Increasing the CO or flow across a stenosis always ________pressure gradient.   Increases the Diastolic  
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