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skin

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Term
Definition
The skin:   Covers the entire body, largest organ of the body, thickness of 1.5-4 mm  
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Skin consists of   Epidermis, dermis, hypodermis  
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epidermis   superficial region consisting of stratified squamous epithelium tissue  
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dermis   underline epidermis and consists of dense irregular connective tissue, strong flexible connective tissue, contains nerves and blood vessels, hair follicles and glands  
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Hypodermis   Subcutaneous layer deep to skin, not part the skin but share some functions, mostly adipose tissue the acts as shock absorber and insulator  
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kertionocytes   Tightly connected by desmosomes, arise from stratum basal (deepest layer of the epidermis), become scale like and die, death of cells occur from lack of blood  
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Melanocytes   Synthesis melanin which protect the nuclear's from UV rays and shelters DNA, these cells are found in stratum basal, spider like  
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Langerhan's cells   they are macrophages, they help to activate your immune system  
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Merkel cells   Present in small numbers at the dermal-epidermal junction, immediately associated with the sensory nerves  
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Layers of the epidermis are (5):   Stratum basale, stratum spinsum, stratum granulosum, stratum lucidum, stratum corneum  
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Stratum Basale   Deepest epidermal layer also called germinitavum because of rapid cell growth, Single row of young keratinocytes  
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Stratum Spinosum (pricky layer)   Several layers thick, cells contain web-like System of intermediate prekeratin filaments attached to desmosomes.  
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Stratum Granulosum (granular layer)   4-6 layers ( thin ), sell appearance is flattened  
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Stratum Lucidum (clear layer)   Only in thick skin, thin, translucent band, a few rows of flat dead keratinocytes. This is only present on thick skin  
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Stratum Corneum (horny layer)   20 to 30 rows of dead, flat, enucleate keratinized membrane sacs, though dead- cells still have functions  
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How many cells do we shed every minute   50,000  
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Created by: carolinegurnsey
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