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integumentary system


The skin: Covers the entire body, largest organ of the body, thickness of 1.5-4 mm
Skin consists of Epidermis, dermis, hypodermis
epidermis superficial region consisting of stratified squamous epithelium tissue
dermis underline epidermis and consists of dense irregular connective tissue, strong flexible connective tissue, contains nerves and blood vessels, hair follicles and glands
Hypodermis Subcutaneous layer deep to skin, not part the skin but share some functions, mostly adipose tissue the acts as shock absorber and insulator
kertionocytes Tightly connected by desmosomes, arise from stratum basal (deepest layer of the epidermis), become scale like and die, death of cells occur from lack of blood
Melanocytes Synthesis melanin which protect the nuclear's from UV rays and shelters DNA, these cells are found in stratum basal, spider like
Langerhan's cells they are macrophages, they help to activate your immune system
Merkel cells Present in small numbers at the dermal-epidermal junction, immediately associated with the sensory nerves
Layers of the epidermis are (5): Stratum basale, stratum spinsum, stratum granulosum, stratum lucidum, stratum corneum
Stratum Basale Deepest epidermal layer also called germinitavum because of rapid cell growth, Single row of young keratinocytes
Stratum Spinosum (pricky layer) Several layers thick, cells contain web-like System of intermediate prekeratin filaments attached to desmosomes.
Stratum Granulosum (granular layer) 4-6 layers ( thin ), sell appearance is flattened
Stratum Lucidum (clear layer) Only in thick skin, thin, translucent band, a few rows of flat dead keratinocytes. This is only present on thick skin
Stratum Corneum (horny layer) 20 to 30 rows of dead, flat, enucleate keratinized membrane sacs, though dead- cells still have functions
How many cells do we shed every minute 50,000
Created by: carolinegurnsey