Kidneys roll in circulation
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| What is kidneys roll in blood pressure? | Increased bp -> increased diuresis and natriuresis -> Decreased BV
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| What is pressure diuresis/natriuresis? | A few mm hg increase -> doubles the effect of renal output.
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| What is the two primary determinants of the long-term arterial pressure level? | Shifting the equilibrium point. That is to change the intake/outtake level in ren.
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| Decribe the arterial pressure in kidney. | CO and peripheral resistant changes while arterial pressure in ren is constant.
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| Define hyper tension. | Blood pressure s>135 d>90
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| Hypertension causes? | 1) heart failure and coronary heart disease 2)increased bp-> cerbral infarkt (stroke) 3) increased bp-> hemorrage in ren
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| Hypertension is caused by? | Excessive accumulation of extracellular fluid in the body.
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| Describe changes in circulary function during volume-loading hypertension! | 1) increased extracellular fluid volume-> increased blood volume -> increased CO -> increased bp actives baroreceptors-> Vasodilatation -> decreased resistance
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| Why does kidney failure cause high pressure? | Kidney can't secrete salt -> hypertension
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| Salt causes? | 1) Stimulation of thirst center in medulla.
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| What is the salts effect on renin-angiotensin system? | Increased salt intake->Increased ECV-> Increased BP-> Decreased renin & angiotensin-> decreased retention of salt and water-> Return of ECV back to normal-> normal BP
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| Why does aldesteronism lead to hypertension? | Tumor or patological disorder in adrenal gland -> increase alderone release-> increased salt&water absorbtion ->hypertension
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| Describe the renin-angiotensin system! | dec. bp->prerenin (stored in juxta glomeruler cells) ->renin (func. enzym) -> angiotensin-I (have a little vasoconstrion effect)-> angiotensin-II (lungs)
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| What does angiotensin-II (prod. lungs) have for effect? | 1)Vasoconstricter (arteriols and little on veins) 2)retention of water & salt (because of renvasoconstrion and better absorbtion) 3) release of aldorone (causes better absorbtion in ren)
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Created by:
Malekian
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