organelle diseases for biology of drugs
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| Tay-Sachs disease | Fatal, genetic, fat storage disease in which fat accumulates in the brain. Infantile TSD is usually fatal by age 2.
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| Faulty organelle in Tay-Sachs disease? | Golgi apparatus
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| Populations affected by Tay-Sachs? | Mostly Eastern European Jewish (Ashkenazi). Also, French Canadian and Louisiana Cajun.
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| Signs/Symptoms of Tay-Sachs | Deteriorating mental and physical abilities
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| Cystic fibrosis | Genetic disease involving defective ion channels which interferes with the passage of water through cells with secretions, resulting in thicker mucous and saltier sweat
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| Faulty organelle in Cystic Fibrosis | membrane ion channel
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| Populations affected by cystic fibrosis | Western European Ancestry
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| Signs/Symptoms of cystic fibrosis | salty skin, difficulty breathing, thick secretions
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| Muscular Dystrophy | genetic disease involving progressive muscle weakness
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| Faulty Organelle in Muscular Dystrophy | cytoskeleton
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| Cytoskeleton | organelle involved with cell structure and movement
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