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Organelle Diseases

organelle diseases for biology of drugs

Tay-Sachs disease Fatal, genetic, fat storage disease in which fat accumulates in the brain. Infantile TSD is usually fatal by age 2.
Faulty organelle in Tay-Sachs disease? Golgi apparatus
Populations affected by Tay-Sachs? Mostly Eastern European Jewish (Ashkenazi). Also, French Canadian and Louisiana Cajun.
Signs/Symptoms of Tay-Sachs Deteriorating mental and physical abilities
Cystic fibrosis Genetic disease involving defective ion channels which interferes with the passage of water through cells with secretions, resulting in thicker mucous and saltier sweat
Faulty organelle in Cystic Fibrosis membrane ion channel
Populations affected by cystic fibrosis Western European Ancestry
Signs/Symptoms of cystic fibrosis salty skin, difficulty breathing, thick secretions
Muscular Dystrophy genetic disease involving progressive muscle weakness
Faulty Organelle in Muscular Dystrophy cytoskeleton
Cytoskeleton organelle involved with cell structure and movement
Created by: jondoh