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Rheumatology

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Question
Answer
Defn Sjogren syndrome   inflam dz of exocrine glands (sicca)  
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If sjogren sx and no other autoimmune dz =   Primary Sjogren  
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If autoimmune dz and sjogren sx =   secondary sjogren  
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Sjogren sx   sicca (dry eyes & mouth (xerostomia); parotid enlargement; poss also fatigue/ myalgias (rare: internal organ involvement: lungs, kidneys, etc  
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Sjogren: Testing: Eyes:   Schirmer’s test: measures tear production on paper; Rose-Bengal staining: shows corneal damage  
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Sjogren: Testing: Mouth:   salivary gland biopsy  
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Sjogren: Testing: Labs:   antibodies to Ro and La  
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Sjogren: Tx: Keratoconjunctivitis sicca:   ocular lubricants, artificial tears  
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Sjogren: Tx: Xerostomia:   liberal fluids; specially-formulated mouthwash, toothpaste, chewing gum (Biotene), oral moisturizers  
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Sjogren: Tx: Systemic sx   steroids; NSAIDs; DMAARDs (usually hydroxychloroquine)  
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Defn Sjogren syndrome   inflam dz of exocrine glands (sicca); usu middle aged F  
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If autoimmune dz and sjogren sx =   secondary sjogren  
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Sjogren sx   sicca (dry eyes & mouth (xerostomia); parotid enlargement; poss also fatigue/ myalgias (rare: internal organ involvement: lungs, kidneys, etc  
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