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True/False: Motor control

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True/False
Answer
Upper motor neuron lesions produce weakness.   True, this is in a pyramidal distribution (weakness of the arm extensors and leg flexors so the patient has flexed arms and extended legs).  
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Upper motor neuron lesions produce fasciculations.   False, fasciculations are not seen with upper motor neuron lesions.  
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Upper motor neuron lesions produce increased spinal reflexes.   True, there is reduced supraspinal inhibition of the reflexes.  
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Upper motor neuron lesions produce spasticity.   True, the muscles become hypertonic because of an increase in motor neuron activity.  
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Upper motor neuron lesions produce wasting.   False, wasting is not a feature of upper motor neuron lesions.  
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Lower motor neuron lesions produce weakness.   True, these produce weakness in the muscles supplied by that nerve.  
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Lower motor neuron lesions produce fasciculations.   True, this represents partial re-innervation by the remaining nerves.  
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Lower motor neuron lesions produce increased spinal reflexes.   False, the spinal arc is disrupted therefore cannot be activated.  
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Lower motor neuron lesions produce spasticity.   False, there is reduced output from the motor neuron so the muscle loses its natural tone.  
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Lower motor neuron lesions produce wasting.   True, spontaneous nerve firing produces trophic changes in muscle fibres. If they are lesioned, the muscles lose this input and atrophy.  
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Upper motor neurons innervate skeletal muscle.   False, these neurons originate from the primary motor cortex and synapse with the lower motor neurons in the spinal cord.  
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Lower motor neurons originate from the dorsal horn of the spinal cord.   False, lower motor neurons originate from the ventral horn.  
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Alpha motor neurons produce forceful contractions of skeletal muscle.   True, they synapse with muscle fibres at the neuromuscular junction.  
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Alpha motor neurons contain motor and sensory fibres.   True  
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Gamma motor neurons cause the contraction of intrafusal fibres.   True  
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Large innervation ratios give fine control over movement.   False, if one neuron innervates many muscle fibres then coarse control of movement is produced.  
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Smaller motor neurons are recruited before larger ones.   True, true for both reflex and voluntary movements.  
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Muscle fibre type is determined by the firing properties of the nerve innervating it.   True  
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Fast fibres contain many mitochondria, high levels of glycolytic enzymes and high levels of myosin ATPase.   True, these features are determined by the firing patterns of the fast fibre nerve.  
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Spontaneous muscle activity can occur in a motor neuron disease.   True, fasciculations and fibrillations are a feature of several degenerative motor neuron diseases.  
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