Steps
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| Muscle Cell is at rest, the SR are pumping calcium ions into sacs | Step 1
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| The motor neuron signals the release of acetylcholine (ACH) into the neuromuscular junction (synaptic cleft) | Step 2
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| ACh stimulates the receptors on the sarcolemma and initiates the electrical impulse | Step 3
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| The nerve impulse travels along the sarcolemma and down the T-tubules | Step 4
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| The impulse triggers the release of calcium into the sarcoplasm | Step 5
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| Calcium binds to troponin (which is the protein that holds the protein tropmyosin in place over activ=ns binding site) | Step 6
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| Tropomyosin shifts exposing the active site on actin | Step 7
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| The head of myosin (energized by ATP) binds to actin (cross-bridge) abd pulls the thin filament (attach to Zplates of sacromere) past them (power stroke) | Step 8
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| In the presence of ATP, each myosin head releases actin and then binds to the next active site (muscle fiber shorten/contract as think and thin filaments slide past eachother) | Step 9
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| The sarcoplasmic reticulum starts actively pumping calcium ions back into the storage sacs. | Step 10
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| As calcium is removed from troponin, this allows tropomyosin to again block the active sites on actin and the muscle relaxes | Step 11
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Created by:
bfergie
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