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ICU Medications

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Drug
Information
Adenocard / Adenosine   Antiarrhythmic Indication: SVT Contraindication: AFib, AV Block Adverse Reactions: Hypotension, transient asystolic pause Dose: 6mg IVP, 12mg IVP - followed by 20ml flush of 0.9% Sodium Chloride  
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Amiodarone / Cordarone   450mg/250ml D5W antiarrhythmic Use: SVT Contraindication: Bradycardia, Cardogenic Shock Adverse Reactions: Hypotension, Bradycardia Bolus: 150mg/100ml D5W over 10 minutes Drip: 1mg/min x 6 hours then 0.5mg/min x 18 hours Max: 2.2 grams in 24 hours  
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Angiomax / Bivalirudin   250mg/50ml Direct Thrombin Inhibitor Contraindication: Active Major Bleeding Adverse Reactions: Bleeding, bradycardia Drip: 1.75mg/kg/hr for up to 4 hours  
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Ativan / Lorazepam   40mg/250ml D5W benzodiazepine Use: Sedation, anxiety, seizure Contraindication: Glaucoma Adverse Reaction: Hypotension, Respiratory depression Drip: max 30mg/hr *dilute in equal parts 0.9 Sodium Chloride for injection  
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Cardizem / Diltiazem   125mg/125ml Calcium Channel Blocker Use: rapid ventricular rate Contraindication: Sick Sinus Syndrome, SBP <90 Adverse Reactions: Bradycardia, CHF, hypotension Drip: Max 15mg/hr Bolus: 0.25mg/kg over 2 minutes (20mg)  
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Diprivan / Propofol   1000mg/100ml Sedative/hypnotic Indication: Deep Sedation Contraindication: egg, soy, and peanut sensitivity, pregnant women Adverse Reaction: bradycardia, hypotension, green urine Drip: max 100mcg/kg/min *Change IV tubing every 12 hours  
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Dobutamine / Dobutrex   1000mg/250ml Sympahomimetic Use: CHF, Cardiogenic Shock Contraindication: hypovolemia, Acute MI Adverse Reaction: tachycardia, HTN, hypotension, chest pain Drip: max 40mcg/kg/min *may lower potassium levels  
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Dopamine / Intropin   400mg/250ml Sympathomimetic Use: hypotension, bradycardia Contraindication: Vtach, Acute MI Adverse Reaction: Tachycardia, HTN, Chest pain Drip: max 20mcg/kg/min  
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Heparin / Heparin Sodium   25,000 units/500ml anticoagulant Use: DVT, PE, Acute MI Contraindication: active bleeding, thrombocytopenia Adverse Reaction: HITS, hemorrhage, thrombocytopenia Drip: based on patients weight *Therapeutic rance = 40-60  
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Integrilin / Eptifibatide   200mg/100ml Glycoprotein IIb/IIIa inhibitor USE: ACS, PCI Contraindication: Active bleeding, stroke within 30 days, dependancy on dialysis Adverse Reaction: bleeding, thrombocytopenia  
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Levophed / Norepinephrine   4mg/500ml Sympathomimetic Use: severe hypotension Contraindication: hypovolemia, periperal vascular thrombosis Adverse Reaction: tachycardia, arrhythmias Drip: max 30mcg/min *monitor VS every 5 minutes  
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Lidocaine / Xylocaine   2gm/500ml antiarrhythmic Use: Ventricular dysrhythmias Contraindication: bradycardia, heart blocks Adverse Reaction: Bradycardia, hypotension, seizure, respiratory depression Bolus: max 3mg/kg Drip: max 1-4mg/min  
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Neo-Synephrine / Phenylephrine   50mg/250ml sympathomimetic Use: sever hypotension Contraindication: Acute MI, CAD Adverse Reaction: Bradycardia, chest pain Drip: 40-60mcg/min  
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Nipride / Nitroprusside   50mg/250ml vasodilator Use: Hypertensive Emergency Contraindication: hypothyroidism, hyponatremia, liver disease Adverse Reaction: hypotension, cyanide toxicity Dose: 0.3-10mcg/kg/min  
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Nitroglycerin / Tridil   50mg/250ml Nitrate Use: Chest pain, HTN, acute MI, heart failure Contraindication: hypovolemai, anemia, hypotension Adverse Reaction: hypotension, headache, tachycardia Drip: max 100mcg/min  
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Procan / Procanamide / Pronestyl   2gm/500ml antiarrhythmic Use: SVT, ventricular dysrhythmias Contraindication: heart blocks, Lupus Adverse Reaction: Bradycardia, hypotension Bolus: 20mg/min not to exceed 17mg/min Drip: 1-4mg/min  
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Reopro / Abciximab   9mg/250ml Glycoprotein IIb/IIIa inhibitor Use: ACS, PCI Contraindications: GI bleed in last 6 weeks, HTN Adverse Reaction: bleeding, thrombocytopenia Dose: varies  
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Succinylcholine / anectine   Neuromuscular blocker Use: assist with mechanical ventilation, facilitation of intubation Contraindication: burn, trauma, glaucoma Adverse Reaction: bradycardia, hyperkalemai Dose: 0.3-1.1 mg/kg IVP *administer sedative first  
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Versed / Midazolam   25mg/250ml Benzodiazepine Use: anxiety, sedation, seizure Contraindication: glaucoma Adverse Reaction: hypotension, dizziness, respiratory depression IVP: 1-2mg every hour PRN Drip: max 0.2mg/kg/hr  
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Zemuron / Rocuronium   Neuromuscular blocker Use: facilitate with intubation, assist with mechanical ventilation Contraindication: hepatic disease Adverse Reaction: hypertension, hypotension, tachycardia, hiccups, nausea Dose: 0.1-0.2 mg/kg *administer sedative first  
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