Neuro of Chronic Pain
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
|
|
||||
|---|---|---|---|---|---|
| Ascending Pain Pathways and what they do = ? | * All are parts to the Anterolateral System .... * Lateral Spinothalamic tract- Pain, temperature..... * Spinothalamic Tract Proper- (Neospinothalamic,lateral)-fast pain (hit hand with a hammer)
...... * Paleospinothalamic Tracts (medial)- slow pain
🗑
|
||||
| Spinothalamic Tract - Fast Pain basics = ? | * Usu A-Deltas (fast pain fiber are primary afferents)
🗑
|
||||
| Spinobulbar Tracts - Slow pain basics = ? | * secondary hyperalgesia... * Mostly by C-Fibers.... * Is a bilateral system
🗑
|
||||
| Responsible for Pain Discrimination = ? | * Spinothalamic (made up of the somatosensory cortex)
🗑
|
||||
| Responsible for emotional and affective components and memory inherent to the painful experience = ? | * Paleospinothalamic (limbic system)
🗑
|
||||
| Descending Pain Modulating Pathway = ? | * role of a biological gate or filter reducing the transmission of pain impulses
🗑
|
||||
| Descending Central Inhibitory Pain Pathways = ? | * Best Characterized: Cortex-PAG-RVM-Spinal cord..... * When PAG is stimulated --> activates RVM --> Release Serotonin To dampen pain at Dorsal horn (One is Sero and another is NE)
🗑
|
||||
| Dopamine and Pain ? | * Dopamine is released in the striatum in response to pain..... * Deactivation of these structures results in hyperalgesia (great pain reduction)
🗑
|
||||
| Diffuse Noxious Inhibitory Control = ? | * Pain inhibits Pain
.... * When a noxious stimuli is sent and processed, the output is to reduce the pain
🗑
|
||||
| Gate Control Theory Segmental Inhibition = ? | * Beta fibers = close the gate…rubbing hand, after it is hit activates the larger Beta fibers, which closes gate (inhibits pain)
🗑
|
||||
| Acute Pain = ? | * Adaptive and Short Lived
🗑
|
||||
| Chronic Pain = ? | * NOT Adaptive and Pain that continues when it should not
🗑
|
||||
| Chronic Pain is ______ driven ? | * Centrally Driven.... * something has happened centrally causing the pain to persist, bc the area is healed up
🗑
|
||||
| Chronic Pain Conditions include = ? | * neuralgias -- chronic fatigue syndrome -- endometriosis -- fibromyalgia -- inflammatory bowel disease -- interstitial cystitis -- TMJ dysfunction -- vulvodynia
🗑
|
||||
| Brain regions associated with pain = ? | * Somatosensory areas S1 and S2 -- Anterior cingulate cortex (ACC) -- Insular cortex (IC)
Prefrontal cortex (PFC) -- Thalamus -- Cerebellum.... * Basically the Limbic System, Thalamus, and the Cerebellum
🗑
|
||||
| Cortical Regions activated with pain: Anterior cingulate gyrus (ACC)basics = ? | * affective-motivational dimension of pain.... * Stimulation leads to the noxious feeling and unpleasantness of pain.... * Lesion of the ACC = Pain wouldn't feel unpleasant
🗑
|
||||
| Cortical Regions activated with pain: Insular Cortex basics = ? | * Responsible for the magnitude of pain (INTENSITY)…… * Lesion here = heightened pain thresholds or the condition of pain asymbolia... * also see lack of empathy in others that get hurt
🗑
|
||||
| ACC and IC are usually activated ? | * together with pain and their functions overlap
🗑
|
||||
| Cortical Regions activated with pain: Prefrontal Cortex = ? | * Has to do to telling your conscious you are in pain, and what you are going to do about it
🗑
|
||||
| What changes are observed in the CNS with Chronic Pain? | * DECREASES IN: Gray Matter and Thalamus Volume..... * INCREASES IN: amygdala excitability and PAG Volume
🗑
|
||||
| Etiology of Chronic Pain = ? | * Defective descending inhibitory pain pathways.... * DNIC pathway are affected (pain inhib pathways)
🗑
|
||||
| Comorbidities with Chronic Pain ? | * Patients with one chronic pain condition have an increased incidence of having a second or third pain condition
.... * may be explained by a shared defect in in descending inhibitory pain pathways
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
thamrick800
Popular Medical sets