Transfusion Medicine II
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| What situation indicates the tranfusion of whole blood? | show 🗑
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| show | The anti-A and anti-B antibodies in the O plasma will eventually react with the recipient's cells causing hemolysis.
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| How much serum is found in a unit of packed red blood cells? | show 🗑
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| What ABO type can recieve type O packed red blood cells? | show 🗑
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| show | Blood type AB
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| What is the general indication for packed red blood cells? | show 🗑
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| How many tranfusions of D-positive blood can be given to an D-negative individual? | show 🗑
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| show | 1)Acquired coagulopathies where PT and PTT > 1.5 times the upper limit of normal 2)Factor replacement for bleeding where no factor concetrate is available.
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| What ABO type can recieve type AB fresh frozen plasma? | show 🗑
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| What ABO type fresh frozen plasma can be safely transfused into a type O recipient? | show 🗑
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| What are the indications for platelet transfusions? | show 🗑
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| What are the ABO compatibilty requirements for safe transfusion of platelet concentrates. | show 🗑
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| show | Yes, a few red cells may be present in platelet concetrates; therefore a D negative patient can be immunized by a platelet product from a D positive donor.
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| show | Antibodies can be formed aganist HLA antigens present on transfused platelets. Once these antibodies are made, they can accelerate platelet destruction.
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| What can prevent alloimmunization to HLA antigens from frequent platelet concetrate transfusion? | show 🗑
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| What are the indications for leukocyte reduced blood products? | show 🗑
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| show | Blood products which have been filtered to remove 3 to 4 logs of white blood cells.
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| What types of blood products require leukocyte reduction? | show 🗑
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| What blood products do not require leukocyte reduction? | show 🗑
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| What is the therapy for febrile nonhemolytic transfusion reaction? | show 🗑
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| show | Febrile nonhemolytic transfusion reaction
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| show | Urticaria
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| What are the consequences of transfusion of ABO incompatible whole blood transfusion? | show 🗑
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| show | typically 7-9 days after transfusion
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| What subtype of immunoglobulin are responsible for the delayed extravascular hemolytic transfusion reaction? | show 🗑
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