Transfusion Medicine I
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| What are the possible genotypes for blood type A? | show 🗑
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| What are the possible genotypes for blood type B? | show 🗑
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| What is the structure of H antigen? | show 🗑
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| What is the structure of A antigen? | show 🗑
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| What is the structure of B antigen? | show 🗑
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| show | True.
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| show | True.
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| show | True.
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| show | Blood type O
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| What is the most common blood type in the United States? | show 🗑
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| show | Blood type AB
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| show | By 6 months of age
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| (T or F) ABO antibodies are only formed after exposure to incompatible red blood cells. | show 🗑
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| show | IgM
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| show | Mixture of IgG and IgM
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| (T or F) The mortality rate of ABO incompatibility depends upon the amount of incompatible blood recieved. | show 🗑
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| What type of hemolysis occurs with tranfusion with incompatible red cells? | show 🗑
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| An assay performed to determine the phenotype of the patient's red cell using IgM antibodies against A and B antigens. | show 🗑
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| show | An assay where the patient's serum is reacted aganist A and B red blood cells to make sure that the reciprocal antibodies are present.
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| What antigen do Rh positive individuals possess? | show 🗑
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| show | Autosomal dominant. The absence of D antigen is due to a deletion in the Rh gene.
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| show | False. Unlike ABO antibodies, synthesis of D antibodies by Rh negative individuals occurs only upon exposure to Rh positive red cells either by transfusion or pregnancy.
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| How is D antigen typing determined on a blood sample? | show 🗑
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| show | It is performed to determine if the serum of a patient contains any potentially clinically significant red cell antibodies other than A or B. 15 antigens are tested.
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| show | 2 or more group O red cells that possess all of the 15 antigens are mixed with the patient's serum. Agglutination or hemolysis will occur when the anti-human globulin is added if clinically significant RBC antibody is present.
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| show | It is performed on every unit of blood ordered. The RBC from the unit to be transfused is mixed with the serum of the patient to detect any incompatibility missed by the antibody screen.
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