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Disease Chapter 15

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Osteomyelitis is an   inflammation of bone and bone marrow.  
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A common cause of osteomyelitis is   staph ( ) aureus  
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Osteomyelitis is a common complication of an   open FX ( ) AKA compound FX.  
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Signs and symptoms of osteomyelitis include:   1. Pain. 2. Chills. 3. Pyrexia ( ). 4. Leukocytosis ( ).  
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A complication of osteomyelitis is bone necrosis ( ) called   sequestrum  
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This infection responds well to   antibiotics.  
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Tuberculosis (TB) is primarily a disease of the   lungs.  
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Pulmonary TB ( ) left untreated can spread to the   bones.  
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Pott’s disease is TB that affects the   vertebral column of children.  
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Pott’s disease can lead to   vertebral deformities and paralysis.  
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These vertebral deformities may require   surgical correction. TB ( ) responds well to antibiotics ( ).  
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Rickets is a disease affecting   infants and young children.  
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Rickets is caused by a deficiency of   Ca ( ) and/or vitamin D.  
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The bones of the child with rickets are   soft and tend to bend causing deformities ( ).  
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The child’s muscles are flaccid ( ) because   muscles need Ca ( ) for proper muscle contraction.  
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Teething may be delayed and there is a characteristic   pot belly.  
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Rickets is associated with   malabsorption syndrome ( ).  
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The most common prophylaxis ( ) and Tx ( ) for rickets is   sunlight ( ) and the RDA ( ) of Ca ( ) with vitamin D.  
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Osteomalacia (OM) is a softening and decalcification of the bones in   adults.  
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The bones particularly affected by OM ( ) include the   vertebral column, pelvis, and legs.  
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The bones tend to   bend, deform, and FX ( ) easily.  
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OM ( ) is associated with   malabsorption syndrome ( ).  
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The most common prophylaxis ( ) and Tx ( ) for OM ( ) is   sunlight ( ) and the RDA ( ) of Ca ( ) with vitamin D.  
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Vitamin D deficiency has been associated with   breast cancer, colon cancer, prostate cancer, MS ( ), OP ( ), heart disease, DM ( ) and HTN  
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Osteitis fibrosa cystica (OFC) usually results from hyperparathyroidism which causes   bone decalcification.  
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Signs and symptoms of OFC ( ) include   nephrolithiasis ( ), bone deformities, and spontaneous FXs ( ).  
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Tx of OFC ( ) includes:   removal of parathyroid tumor or parathyroidectomy  
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Osteoporosis (OP) is a   loss or thinning of BMD ( ) AKA osteopenia ( ).  
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Risk factors for OP include: 1 - 7   1. Female gender 2. Family hx 3. Deficient vitamin D and/or Ca in the diet. 4.Sedentary lifestyle 5.Smoking. 6. Thin or small frame. 7. 1-2 ETOH ( ) drinks/day doubles the risk of OP  
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Risk factors for OP include: 8 -11   8.Excessive caffeine consumption. 9.Being Caucasian or Asian. 10.Estrogen level reduction associated with menopause. 11.Prolonged use of SAIDs Al antacids, diuretics, tetracycline antibiotics, and antiseizure medications.  
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The degree of OP ( ) risk also depends on amount of BMD ( ) acquired between ages   25-35.  
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Signs and symptoms of OP ( ) include:   1. A predisposition to FXs especially the wrists, pelvis, and vertebrae. 2. Kyphosis ( ). 3. Loss of HT  
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Dx of OP ( ) depends on   patient hx ( ), bone densitometry, and DEXA  
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Tx of OP ( ) includes:   1. Sunlight and 500mg x 3 daily of Ca ( ) with vitamin D.Do not exceed 2500mg/day. 2. Regular exercise. 3. ERT AKA HRT for postmenopausal women. 4. The use of calcitonin in extreme cases.  
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Bone density tests are recommended for the following:   1. Type I DM ( ). 2. Liver or kidney disease. 3. Menopause. 4. Over age 50.  
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Paget’s disease is AKA   osteitis deformans.  
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Paget’s disease is an idiopathic ( ) possibly genetic overproduction of   abnormal bone tissue.  
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Signs and symptoms of Paget’s disease include:   1. Osteomalacia ( ). 2. Easy FXs ( ). 3. Deformities of the legs. 4. Abnormal curvatures in the vertebral column  
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A complication of Paget’s disease is   OS ( ) which is a primary bone malignancy.  
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The most common benign bone tumor is an   osteoma.  
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An osteoma can be   asymptomatic  
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If pain, decreased mobility, or swelling occurs,   surgery is performed to remove the tumor.  
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A primary bone malignancy is called an   osteogenic sarcoma (OS).  
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OS is more common in   young adults  
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A common sign of OS ( ) is easy   FXs ( ).  
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Tx ( ) of OS includes:   1. Chemotherapy ( ). 2. Surgical removal of tumor  
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Most commonly, malignant bone tumors are secondary tumors that have   metastasized ( ) from another site.  
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These secondary bone tumors cause   easy FXs ( ) and extreme pain  
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The Px ( ) for a secondary bone malignancy is   poor  
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Arthritis is an   inflammation of a joint(s).  
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Arthritic symptoms include:   pain, edema ( ), and stiffness of the joints especially upon waking.  
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Joints commonly affected by arthritis include:   lumbar vertebrae, hips, knees, and fingers.  
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Rheumatoid arthritis (RA) is considered   autoimmune and genetic.  
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Rheumatoid arthritis (RA) is the most serious form of arthritis and can cause   contractures  
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Signs and symptoms of RA ( ) include   pain, edema ( ), erythema ( ), warmth, and stiffness of the joints especially on waking.  
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RA ( ) is systemic so it can affect   all of the joints.  
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RA ( ) can cause scar tissue to fuse the ends of the bones causing   immobility  
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RA can cause enlargement of the joints called   rheumatoid nodules.  
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Tx of RA ( ) includes:   1. ROM ( ) exercises. 2. Rest. 3. NSAIDs ( ) { }. 4. Enbrel, Orencia, Humira & Simponi  
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Osteoarthritis (OA) is the most common form of arthritis and can accompany   aging.  
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OA commonly affects joints in the   fingers, neck, low back, knees, and hips.  
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Other causes of OA ( ) include:   1. Chronic irritation or injury. 2. Heredity. 3. Obesity  
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The primary symptoms of OA are   pain and stiffness of the joint(s).  
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OA ( ) can cause DJD ( ) causing irregular bone deposits called   spurs.  
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There is no cure for OA but the Tx ( ) includes:   1.ROM exercises. 2.Rest. 3.Heat therapy. 4.Vitamins D,C,E, and beta carotene. 5. Green tea. 6. SAIDs + NSAIDs 7. THR + TKR  
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Gout is a form of arthritis that usually affects great toes and is caused by hyperuricemia causing deposits of uric acid crystals in the   joints and kidneys.  
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The onset of gout is usually sudden and frequently affects men over the age of   40  
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Complications of gout include:   1. Joint deformities. 2. Kidney damage.  
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Tx ( ) of gout includes:   1. Refrain from consuming organ meat, anchovies, sardines, and beer. 2. Antigout medication  
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Carpal tunnel syndrome (CTS) is caused by compression of the   median nerve in the wrist.  
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CTS is more common in women and usually strikes around ages   35-40.  
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Signs and symptoms of CTS ( ) include:   numbness and tingling in the hand progressing to pain that can radiate up the arm to the shoulder  
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CTS is a   RSI  
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CTS ( ) usually develops when a   wrist is kept in a flexed position for extended periods to perform repetitive tasks.  
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High risk groups for CTS include:   1. Computer users. 2. Beauticians. 3. Dentists. 4. Playing musical instruments. 5. Use of vibrating tools.  
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Dx of CTS ( ) is confirmed with:   1. A hx ( ) of repetitive hand movements with a flexed wrist. 2. EMG  
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Tx ( ) of CTS includes:   1. Proper wrist alignment. 2. Avoidance of repetitive movements. 3. Braces and splints. 4. NSAIDs ( ) { }. 5. Surgery.  
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A herniated intervertebral disk (HID) is AKA a   slipped or ruptured or bulging disk.  
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A HID occurs more frequently in the   lower lumbar region of the back and is many times caused by poor body mechanics.  
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The primary complication of a HID ( ) is   pressure exerted on the spinal cord and/or spinal nerve(s) causing weakness, tingling, numbness, and extreme pain.  
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A common spinal nerve affected by a HID is the sciatic nerve causing   sciatica  
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Tx of a HID ( ) includes:   1. Bed rest on a firm mattress. 2. Muscle relaxants 3. Narcotic analgesics 4. Heat application. 5. Trx 6. TENS 7. Surgery  
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Muscular dystrophy (MD) is a hereditary disease of which there are several forms causing   muscle degeneration ( ) which totally disables the individual  
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The most common and serious form of MD ( ) is called   Duchenne.  
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MD ( ) can appear at any age but generally starts appearing at age   3 to 5.  
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Most individuals with MD do not live to   adulthood.  
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Death is caused by the effect of MD on the   heart and respiratory muscles.  
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Dx of MD ( ) is confirmed by an   EMG ( ) and muscle Bx  
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Tx ( ) of MD includes:   PT ( ), OT ( ), and orthopedic assistance devices  
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Myasthenia gravis (MG) is an   idiopathic ( ) autoimmune neuromuscular disorder.  
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MG occurs more often in   women.  
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MG is caused by a defect in the   transmission of nerve impulses to the muscles.  
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MG ( ) has been linked to   abnormal antibodies produced by the thymus.  
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Muscles commonly involved in MG include:   1. Eye movement. 2. Eyelid movement. 3. Facial expressions. 4. Chewing. 5. Talking. 6. Swallowing.  
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Tx ( ) for MG ( ) includes:   1. Thymectomy ( ). 2. Immunosuppressants  
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A hernia is a   protrusion of a structure through the tissue in which it is normally enclosed.  
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A HH ( ) is a   protrusion of the stomach through the diaphragm AKA diaphragmatic hernia.  
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An UH ( ) is a   protrusion of the intestine through the umbilicus.  
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An IH ( ) usually refers to a   protrusion of the small intestine into the scrotum.  
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A strangulated ( ) hernia can cause   ischemia ( ) and/or necrosis ( ) to the tissue it surrounds.  
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Tx ( ) of a hernia includes:   1. Abdominal supports ( ). 2. Hernioplasty  
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An acute contagious skin disease caused by staph ( ) + strep ( ) especially in children is   impetigo.  
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Impetigo is characterized by:   1. Erythema 2. Oozing vesicles ( ). 3. Pustules ( ) with a honey colored crust.  
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Tx ( ) of impetigo includes:   1. Wash with soap and water. 2. Keep lesions dry ( ). 3. Topical antibiotics  
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Lyme disease is a bacterial disease transmitted by the bite of a   deer tick.  
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Signs and symptoms of Lyme disease usually occur 3-30 days after exposure and include:   1. “Bull’s eye rash” 2. Flu like signs and symptoms such as: a.Malaise b. Cephalalgia c. Chills. d. Pyrexia e. Arthralgias f. Myalgias ( ). g. Lymphadenopathy  
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Treatment (Tx) of Lyme disease includes   antibiotics  
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Untreated Lyme disease can cause permanent damage to the   heart, joints, and nervous system.  
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HSV I causes herpetic stomatitis AKA   “cold sores” or “fever blisters”  
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Herpetic stomatitis is usually found near the   oral labiae  
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The HSVI ( ) can be dormant in the body for months but frequently becomes active when a person is under   stress or when their immune system is weakened  
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Treatment (Tx) of the herpes simplex virus I (HSVI) includes   antiviral drugs  
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Tinea refers to   fungal infections.  
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Tinea corporis is AKA   ringworm.  
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Tinea corporis causes   erythematous ( ) ringed shaped pruritic ( ) lesions.  
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Tinea pedis is AKA   athlete’s foot.  
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Tinea pedis frequently attacks the skin between the toes causing   fissures ( ), pruritus ( ), and pain.  
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Tinea cruris is AKA   jock itch.  
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Tinea cruris causes   erythematous ( ) ring-like areas with vesicles  
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Areas of the body susceptible to tinea are usually   warm, dark, and moist environments.  
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Tx ( ) of tinea includes:   1. Keeping susceptible areas dry. 2. Topical antifungal medications  
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Pediculosis is AKA   lice.  
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Pediculosis ( ) can infest the   head, pubic area ( ), and the body.  
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Head lice are common among children and are transmitted by direct contact or fomites such as   combs, scarves, hats, and bed linen.  
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The primary symptom of pediculosis ( ) is   pruritus  
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Pediculosis (lice) are difficult to see but their white eggs ( ) can be located on the   hair shaft.  
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Tx ( ) of pediculosis ( ) includes:   1. Medicated shampoos 2. Use of a fine toothed comb. 3. Washing clothes in hot water ( ) and machine drying. 4. Leave the house for 55 hours to allow the lice to die.  
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Some studies show that lice are becoming   resistant to the medicated shampoos.  
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Scabies is a contagious skin infestation caused by the   “itch mite.”  
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Signs and symptoms of scabies include   vesicles ( ), pustules ( ), and intense pruritus  
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Scabies are usually transmitted by   skin to skin contact.  
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Tx ( ) of scabies includes:   1. Scrubbing with medicated soaps and shampoos ( ) in hot baths. 2. Washing clothes in hot water ( ) and machine drying.  
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Allergic contact dermatitis (ACD) is a noncontagious inflammation of the skin caused by an   allergic response.  
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Common allergies include:   1. Plants such as poison ivy or oak 2. Chemicals found in clothing dyes, soaps, and perfumes. 3. Metals such as nickel found in costume jewelry etc.  
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Signs and symptoms of ACD ( ) include:   1. Erythema ( ). 2. Vesicles ( ). 3. Pruritus  
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Treatment (Tx) of ACD ( ) includes:   1. Removal of the allergen. 2. Topical SAIDs ( ) { }. 3. Antihistamines ( ). 4. Antipruritic medications  
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Atopic dermatitis (AD) is AKA   eczema.  
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Eczema is an idiopathic ( ) skin disorder causing   erythematous ( ), dry, and crusted patches on the skin.  
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AD ( ) usually affects those with   allergies and asthma.  
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Eczema outbreaks will disappear in half of all children effected by   adolescence.  
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Tx ( ) of atopic dermatitis (AD) includes the use of   SAIDs  
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A nevus is AKA   mole.  
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A nevus ( ) is a benign skin lesion that can become   malignant.  
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Signs and symptoms that indicate a possible change of a nevus ( ) to a malignant lesion include:   1. Change in the size or shape. 2. Pruritus ( ). 3. Soreness. 4. Discharge. 5. Darkening of the nevus  
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The ABCDEs of moles include:   Asymmetry or one half does not match the other half. Border or edges are ragged, blurred, or irregular. Color is not the same throughout. Diameter is larger than the eraser of a pencil. Elevated or raised from the skin.  
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Tx ( ) of a suspect nevus ( ) involves:   surgical removal or cryosurgery  
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Basal cell carcinoma (BCC) is the most common skin cancer that is   slow growing and usually nonmetastasizing.  
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BCC ( ) usually develops on the face or neck of light skinned men ( ) who are   over exposed to UV ( ) light  
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Treatment (Tx) of basal cell carcinoma (BCC) involves:   1. Surgical removal of the tumor. 2. Radiation therapy. 3. Chemotherapy  
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Squamous cell carcinoma (SCC) is a more serious skin lesion because it   metastasizes ( ) through the lymph vessels.  
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SCC ( ) usually develops on the face, ears, neck, lips, and back of the hands of light skinned men ( ) who are   over exposed to UV ( ) light  
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Treatment (Tx) of SCC ( ) involves   1. Surgical removal of the tumor. 2. Radiation therapy. 3. Chemotherapy  
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Malignant (metastatic) melanoma (MM) is the most serious form of skin cancer because it   metastasizes ( ) early.  
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MM ( ) can develop from a nevus ( ) and is associated with   overexposure to UV ( ) light ( ) in Caucasians  
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Treatment (Tx) of malignant (metastatic) melanoma (MM) involves:   surgical removal of the tumor and surrounding lymph nodes.  
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The prognosis (Px) for MM ( ) depends on the   degree of metastasis  
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Tanning beds emit ____-____% more UVA rays than the sun.   50-75  
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Exposure to tanning beds for people under 30 increases skin cancer risk   75%.  
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To protect your skin from UVA + UVB, sunscreen should contain   mexoryl or avobenzone.  
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Acne vulgaris (AV) is caused by a clogging of the   sebaceous ( ) glands.  
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Characteristics of AV ( ) include:   1. Comedones ( ) indicate noninflammatory acne. 2. Pustules ( ) indicate inflammatory acne.  
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Treatment (Tx) of AV ( ) includes:   1. Benzoyl peroxide. 2. Stridex. 3. Keeping the hands away from the face. 4. Gentle cleaning of the skin twice a day.  
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Rosacea is an idiopathic ( ) cyclic progressive inflammatory skin disease that causes   facial erythema ( ), edema ( ), papules ( ), pustules ( ), and pain.  
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Treatment (Tx) of rosacea includes:   1. Avoidance of triggers ( ). 2. Topical vitamin A ( ). 3. Oracea.  
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Psoriasis is an idiopathic ( ) autoimmune chronic ( ) skin disease with a hereditary basis of which there is no   cure.  
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The psoriasis lesions are   erythematous ( ) patches with white or silvery scales.  
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The psoriasis lesions primarily form on the   elbows and knees but the trunk, arms, legs, and scalp can be affected.  
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Psoriasis can be exacerbated ( ) by:   1. Stress. 2. Changes in climate. 3. NSAIDs ( ). 4. Injuries to the skin. 5. Infections.  
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Treatment (Tx) of psoriasis includes controlling lesions with:   1. Coal-tar medications ( ). 2. SAIDs ( ). 3. UV light therapy  
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