Pulmonary V - Neoplasia
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| show | Metastatic carcinoma
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| show | (1) multiple nodules (2) occurs bilaterally
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| show | Lung cancer
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| (T or F) The incidence of lung cancer is rising in both males and females. | show 🗑
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| show | 60% are determined to have operable lesions, but only 8 to 15% are cured.
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| Carcinogens in cigarette smoke | show 🗑
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| (T or F) Passive smoking has not been shown to increase the incidence of lung cancer in non-smokers | show 🗑
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| Etiology of Lung Cancer | show 🗑
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| show | Asbestos + smoking increases risk of lung cancer by 55 times than that of non-smoking/non-exposed person. There is a 5-fold synergistic effect of asbestos and tobacco.
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| Location of Squamous Cell Carcinoma of the Lung | show 🗑
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| show | Squamous Cell Carcinoma of the Lung
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| show | Adenocarcinoma of the lung
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| Location of Small cell (oat cell) Carcinoma of the lung | show 🗑
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| show | Small cell (oat cell) carcinoma of the lung
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| show | (1) Serotonin (2) ACTH (3) ADH (4) MSH (5) Calcitonin
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| show | 50% occur centrally in the major bronchi; others occur more peripherally
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| Type of primary lung tumor that is an undifferentiated tumor that may have squamous or adenocarcinoma differentiation or a mixture of both. Neuroendocrine differentiation also occurs. Electron microscopy is necessary to distinguish these features. | show 🗑
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| show | Tumor typically occurs at the periphery
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| show | Bronchioloalveolar Carcinoma
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| Characteristics of Mucinous subtype of Bronchioloalveolar Carcinoma | show 🗑
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| show | Lesions are typically solitary. 5-year survival is 28-69%.
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| Location of Carcinoid tumor of the lung | show 🗑
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| show | Carcinoid tumor of the lung
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| show | (1) 5-hydroxytryptophan (2) ACTH (3) MSH (4) MSH (5) Insulin (6) ADH (7) Growth hormone (8) Glucagon (9) Catecholamines (10) Kinins
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| Symptoms of Carcinoid Syndrome | show 🗑
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| show | False. Carcinoid syndrome only occurs when the tumor metastasizes (usually to the liver). Clinical disease due to vasoactive peptides/amines, and serotonin secreted by the tumor.
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| show | Pulmonary Hamartoma
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| show | Cytology from sputum samples, bronchial brushings/wash, fine needle aspiration. Transbronchial biopsy, mediastinosccopy or Scalene Lymph node biopsy, surgical resection (wedge<lobectomy<pneumonectomy)
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| show | Used to obtain cytology samples from centrally located lung tumors. Diagnostic yield is 79-90%
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| When is fine needle aspiration most useful for diagnosis of lung disease? | show 🗑
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| show | Tumor proven by the presence of malignant cells in bronchopulmonary secretions, but not visualized roentgenogrphically or bronchoscopically, or any tumor that cannot be assessed as in retreatment stages.
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| T0 staging of lung cancer | show 🗑
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| What is T stage would classify a recurrent lung carcinoma occurring after treatment? | show 🗑
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| show | Carcinoma in situ
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| show | Tumor size: <3.0 cm. No evidence of invasion to surrounding structures. Must be found proximal to a lobar bronchus at bronchoscopy
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| T2 staging of lung cancer | show 🗑
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| T3 staging of lung cancer | show 🗑
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| T4 staging of lung cancer | show 🗑
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| N0 staging of lung cancer | show 🗑
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| N1 staging of lung cancer | show 🗑
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| show | Metasis to ipsilateral Mediastinal lymph nodes and subcarinal lymph nodes
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| N3 staging of lung cancer | show 🗑
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| show | 48%
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| 5 year survival rates for stage II lung cancer | show 🗑
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| show | 12%
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| 5 year survival rate for stage IV lung cancer | show 🗑
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| Clinical presentation of more centrally located lung tumors | show 🗑
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| show | Typically asymptomatic until tumor becomes necrotic (fever or hemoptysis). Dyspnea when sufficient lung parenchyma is involved.
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| Clinical presentation of intrathoracic spread of lung neoplasm | show 🗑
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| Superior Vena Cava Syndrome | show 🗑
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| Pancoast Syndrome | show 🗑
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| Horner’s Syndrome | show 🗑
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| Common sites of Metastasis of Lung Cancer | show 🗑
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| Paraneoplastic syndromes of lung cancer | show 🗑
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