False. Patients with changing or decreased kidney function must be monitored. Also, very large or very small and pregnant patients may need dose adjustments
What is the half-life of Fondaparinux (Arixtra)?
15-18 hours
What is the mechanism of Bivalirudin?
Reversible Direct Thrombin(IIa) Inhibitors
How is Lepirudin excreted?
Renally
What are the contraindications to thrombolytic therapy?
1)Major internal bleeding in the last 6 mo 2)Intracranial or intraspinal disease 3)Operation or biopsy in the preceding 10 days 4)HTN (sys >200, dia>110) 5)Active endocarditis 6)Pericarditis 7)Aneurysm 8)Presence of bleeding disorder
How are the anticoagulant effects monitored by fondaparinux (Arixtra)?