Question | Answer |
What is Erythropoiesis? | RED Blood Cell production |
Where do Erythrocytes develop? | Spleen in Fetuses, RED Bone Marrow in Adults |
How do RBC develop? | Hemocytoblast (stem cells) --> Erythroblast --> Reticulocyte --> Erythrocyte |
At what stage in RBC formation does the Hemoglobin form? | Erythroblast |
At what stage in RBC formation is the Nucleus expelled? | Reticulocyte |
How long does it take for and Erythrocyte to mature? | 5 days |
What is Hemoglobin? | RED, Iron containing pigment & Protein |
What is the Heme (in Hemoglobin) and what is its function? | RED, Iron-containing Pigment - carries O2 |
What is the function of Globin (in Hemoglobin)? | Protein portion - carries CO2 |
What is Erythropoietin? | a Hormone from the Kidney which STIMULATES RBC Production |
Where does RBC destruction take place? | in Liver or Spleen |
What happens as RBC are destroyed? | 1. Macrophages PHAGOCYTIZE worn/damaged cells; 2. Globin RETURNED to Circulation; 3. Heme recycled/stored; 4. Bilirubin excreted in Bile |