Term | Definition |
Blood | traveling mobile unit with many functions
Nutrients/Oxygen In, Wastes Out |
5 blood functions | *Transporter, oxygen delivery, CO2 out, protection, acid-base balance, hormones, and dissolves nutrients, & regulates body temperature |
3 general characteristics | 38C, 100.4 F( normal temp), high viscosity, & slightly alkaline pH(7.35-7.45) |
Plasma | (water & proteins), 55% of blood
Water most component, albumin most protein
Serum(fibrinogin clots) |
Formed Elements | (solids), 45% of blood, Erythrocytes, leukocytes, & platelets |
Composition of Blood | Plasma: water, albumin protein, nutrients, gases, hormones, & electrolytes
Buffy Coat: WBC's & platelets
Hematocrit: RBC's |
Protein functions | clotting, Immune system transporter, regulate fluid volume |
Buffy Coat | WBC (fight) & Platelets (patch)
Beige color, & less than 1% of blood volume |
Hematocrit | heaviest so they sink to bottom during fractionation.
400 billion platelets, 200 billion RBC, & 20billion WBC (daily). |
Blood Cell Formation | Hemopoiesis: Red Bone Marrow-produce all types of blood cells. Ends of long and flat bones.
Lymphatic Tissue- produce lymhocytes. Spleen, lymph nodes, and thymus gland. |
Stem Cells in Red Bone Marrow | Reticulocytes= Immature
Thrombocytes= Platlet
Never(60) Let(30) My(5) Engine(2) Blow(2)!
Neutrophils, Lymphocytes, Monocytes, Eosinophils, & Basophils |
Erythrocytes | deliver oxygen, remove co2
blood has more RBC than any other formed element
cytoskeleton=strechanle making it flexible, coming back to its shape. |
RBC's | Disc Shape, No Nucleus/DNA, lives 120 days |
Hemoglobin | 1/3 of RBC filled with hemoglobin-red color
4 proteins=globins, each gobin bound to iron molecule=heme, each heme can bound to one oxygen molecule. 1 hemoglobin can carry 4 oxygens |
Normal Blood | Hematocrit: F37-48%, M45-52%
Hemoglobin: F12-16 g/dl, M13-18 g/dl
RBC count: F4.2-5.4 million/mm, M4.6-6.2 million/mm
Women lose more blood which lowers hematrocrit levels. |
Iron Requirements | Iron is oxyen carrier
dietary iron is required for hemoglobin synthesis, 5-20 mg from food each day |
Sickle Cell Disease | Inheritate, stiff and inflexible, does not return to its shape
No oxygen=pain |