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Blood
Chapter 19
| Term | Definition |
|---|---|
| Blood | traveling mobile unit with many functions Nutrients/Oxygen In, Wastes Out |
| 5 blood functions | *Transporter, oxygen delivery, CO2 out, protection, acid-base balance, hormones, and dissolves nutrients, & regulates body temperature |
| 3 general characteristics | 38C, 100.4 F( normal temp), high viscosity, & slightly alkaline pH(7.35-7.45) |
| Plasma | (water & proteins), 55% of blood Water most component, albumin most protein Serum(fibrinogin clots) |
| Formed Elements | (solids), 45% of blood, Erythrocytes, leukocytes, & platelets |
| Composition of Blood | Plasma: water, albumin protein, nutrients, gases, hormones, & electrolytes Buffy Coat: WBC's & platelets Hematocrit: RBC's |
| Protein functions | clotting, Immune system transporter, regulate fluid volume |
| Buffy Coat | WBC (fight) & Platelets (patch) Beige color, & less than 1% of blood volume |
| Hematocrit | heaviest so they sink to bottom during fractionation. 400 billion platelets, 200 billion RBC, & 20billion WBC (daily). |
| Blood Cell Formation | Hemopoiesis: Red Bone Marrow-produce all types of blood cells. Ends of long and flat bones. Lymphatic Tissue- produce lymhocytes. Spleen, lymph nodes, and thymus gland. |
| Stem Cells in Red Bone Marrow | Reticulocytes= Immature Thrombocytes= Platlet Never(60) Let(30) My(5) Engine(2) Blow(2)! Neutrophils, Lymphocytes, Monocytes, Eosinophils, & Basophils |
| Erythrocytes | deliver oxygen, remove co2 blood has more RBC than any other formed element cytoskeleton=strechanle making it flexible, coming back to its shape. |
| RBC's | Disc Shape, No Nucleus/DNA, lives 120 days |
| Hemoglobin | 1/3 of RBC filled with hemoglobin-red color 4 proteins=globins, each gobin bound to iron molecule=heme, each heme can bound to one oxygen molecule. 1 hemoglobin can carry 4 oxygens |
| Normal Blood | Hematocrit: F37-48%, M45-52% Hemoglobin: F12-16 g/dl, M13-18 g/dl RBC count: F4.2-5.4 million/mm, M4.6-6.2 million/mm Women lose more blood which lowers hematrocrit levels. |
| Iron Requirements | Iron is oxyen carrier dietary iron is required for hemoglobin synthesis, 5-20 mg from food each day |
| Sickle Cell Disease | Inheritate, stiff and inflexible, does not return to its shape No oxygen=pain |
Created by:
Asuzenam
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