Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Urinalysis 2
Urine protein and Quality Control
| Question | Answer |
|---|---|
| Define proteinuria | Protein in the urine |
| What size protein go through the glomerular | LMW-low molecular weight proteins; glomerulus prevent passage of HMW > 69,000 amu |
| What amount of protein is usually found in the urine | None- any amount greater than trace- (small) considered significant |
| What happens to the protein that is in the filtrate | reabsorbed from the proximal convoluted tuble to the distal convoluted tuble |
| What does persistent proteinuria indicate | renal or kidney disease |
| What urine sample should be tested for protein | First morning |
| What are the causes of transient proteinuria | Physiological state- renal disease, strenuous exercise, orthostitic, dehydration, UTI, acute illness with fever |
| What is orthostatic proteinuria | Protein excreted when upright not lying down |
| Urine specimens show what results in orthostatic protein uria | First morning- neg; 2 hours later- positive |
| Nephrotic syndrome is the nutritional and clinical condition that results from what | Continued massive proteinuria- two or more grams of albumin (plasma protein)/ day leaving the body |
| In nephrotic syndrome when the glomerulus is inflamed, which protein is found in the urine | albumin 60- 90 percent of the time. Slightly larger than pores |
| Describe Bence Jones Proteins | LMW Low molecular weight- portion of a globulin. Seen in disease called multiple myeloma |
| What is the colorimetric test | Dipstick test |
| What is the principle behind the colorimetric test | Protein error of indicators -citrite buffer PH3 yellow; tetrabromphenol PH4 blue |
| What protein is detected by the colormetric test | albumin 60- 90 percent of the time because they are the smallest |
| What reaction does alkaline, highly buffered urine; Bence Jones or globulins cause on dipstick | alkaline- false pos. visibly bloody urine, chlorhexidine skin cleaners; Bence Jones, mucoproteins. |
| What is CLIA '88 | Clinical Laboratory Improvement Amendments developed 88- Federal Regulations. Applies to all laboratories, for accuracy and reliability of lab results |
| CLIA '88 includes requirements for which three areas of the laboratory | Personnel, Quality Control, Proficiency Testing (PC)-outside ascessing |
| How long must quality control records and patient values be kept | 2 years |
| What kind of information should the procedure manual contain | Type of specimen, Refrig. or preservative, Testing procedures, Interpertations of results, possible sources of interference |
| How often should urinalysis controls be checked and recorded | Should be done according to manufacturer- Siemens pos. neg. control whenever you open new jars- each new lot, shipment, monthly if stored more than 30 days |
| What should you record if a control result is out of range | What corrected action was taken |
| Waived Certificate | Not life threatening CW/COW- can only perform waived test |
| Non- Waived Certificate | More complex, more training required- unannounced bieninnial inspections |
Created by:
bossy777
Popular Medical sets