Help
Options
Didn't know it?
click below
click below
Knew it?
click below
click below
Don't Know
Remaining cards (0)
Know
retry
shuffle
restart
0:00
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
BIO202-CH16-cAMP
BIO202 - CH16 - Cyclic AMP - Marieb/Hoehn - RioSalado - AZ
| Question | Answer |
|---|---|
| What is cyclic AMP? | Intracellular 2nd messenger - mediates effects of 1st (extracellular) messenger; formed from ATP by membrane enzyme (adenylate cyclase). |
| Except for thyroid hormone, all amino-acid based hormones exert their signaling effects through __. | intracellular 2nd messengers |
| Name the 3 plasma membrane components that interact in cyclic AMP (cAMP). | Hormone receptor, G protein (signal transducer) & adenylate cyclase (effector enzyme) |
| What is the first messenger in cyclic AMP signaling? | The hormones binding to its receptor |
| What does the binding of a hormone cause in cAMP signaling? | The receptor to change shape & bind to G protein |
| G protein is activated as __ is displaced by high energy compound __. | GDP (guanosine diphosphate), GTP (guanosine triphosphate) |
| G protein behaves like a light switch. It is off when __ is bound to it & on when __ binds. | GDP, GTP |
| Activated G protein binds to what? | the effector enzyme adenylate cyclase |
| G proteins can __ or __ adenlyate cyclase. | stimulate or inhibit |
| If activated, adenylate cyclase generates __. | cAMP (2nd messenger) from ATP |
| cAMP triggers activation of __. | Protein Kinase A |
| What are protein kinases? | Enzymes that phosphorylate (add phosphate group) various proteins |
| Active protein kinase A triggers what? | Responses of target cell - opens ion channels, activates, enzymes, etc. |
| Each activated adenylate cyclase generates __. | Large #s of cAMP molecules & can catalyze 100s of reactions. |
| Theoretically, one hormone molecule binding can generate __. | millions of final product molecules. |
| cAMP is rapidly degraded by __. | phosphodiesterase - intracellular enzyme |
| Since phosphodiesterase rapidly destroys cAMP, continued cellular activity is prompted by __. | continued production of hormones. |
| Some G proteins inhibit adenylate cyclase & __. | reduce cAMP concentration. |
Created by:
Ladystorm
Popular Anatomy sets